Matters Arising: Zhu et al, "A novel gene variation of TNFα associated with ankylosing spondylitis: A reconfirmed study"

Brown, M A (2008) Matters Arising: Zhu et al, "A novel gene variation of TNFα associated with ankylosing spondylitis: A reconfirmed study". Annals of the Rheumatic Diseases, 67(3), p. 434.

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Abstract

In a recently published study1 involving 79 ankylosing spondylitis (AS) patients and 132 unrelated healthy blood donors, Zhu et al report association of a tumour necrosis factor α (TNFα) single nucleotide polymorphism (SNP), rs1799724, with AS.1 I have many concerns with this paper and its conclusions...

Impact and interest:

3 citations in Web of Science®
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ID Code: 87726
Item Type: Journal Article
Refereed: Yes
Additional Information: No file attached.
Keywords: biological marker, HLA B antigen, HLA B27 antigen, HLA B60 antigen, tumor necrosis factor alpha, allele, ankylosing spondylitis, blood donor, clinical study, gene linkage disequilibrium, genetic association, genetic variability, genotype, heterozygosity, homozygosity, human, letter, major histocompatibility complex, medical error, priority journal, single nucleotide polymorphism, genetic predisposition, genetics, note, Genetic Predisposition to Disease, Humans, Linkage Disequilibrium, Polymorphism, Single Nucleotide, Spondylitis, Ankylosing, Tumor Necrosis Factor-alpha
ISSN: 0003-4967
Divisions: Current > Schools > School of Biomedical Sciences
Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 25 Sep 2015 01:21
Last Modified: 16 Feb 2016 01:59

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