Matters Arising: HLA-DR-DQ haplotypes and genotypes in Finnish patients with rheumatoid arthritis

Harney, S., Wordsworth, B. P., Brown, M A, Laivoranta-Nyman, S., Ilonen, J., Hermann, R., Möttönen, T., Toivanen, A., Tuokko, J., Luukkainen, R., Hakala, M., Hannonen, P., Korpela, M., & Yli-Kerthula, U. (2005) Matters Arising: HLA-DR-DQ haplotypes and genotypes in Finnish patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 64(4), p. 655.

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We read with great interest the paper by Laivoranta-Nyman et al.1 They studied Finnish patients with rheumatoid arthritis (RA) and controls, and suggested that there exist susceptibility, neutral and protective HLA-DR-DQ haplotypes that do not match the predictions of current hypotheses for the mechanism of association of the HLA class II region and RA...

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ID Code: 87737
Item Type: Journal Article
Refereed: Yes
Additional Information: No file attached.
Keywords: HLA antigen class 2, HLA DQ antigen, HLA DR antigen, major histocompatibility antigen class 3, controlled study, Finland, gene frequency, genetic susceptibility, genotype, haplotype, human, letter, major clinical study, priority journal, rheumatoid arthritis, statistical analysis, Arthritis, Rheumatoid, Genetic Predisposition to Disease, Haplotypes, HLA-DQ Antigens, HLA-DR Antigens, Humans
ISSN: 0003-4967
Divisions: Current > Schools > School of Biomedical Sciences
Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 25 Sep 2015 00:20
Last Modified: 25 Sep 2015 00:20

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