Genetics of ankylosing spondylitis

Brown, M.A., Wordsworth, B.P., & Reveille, J. D. (2002) Genetics of ankylosing spondylitis. Clinical and Experimental Rheumatology, 20(6SUP28), S43-S49.

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Abstract

Ankylosing spondylitis is a common inflammatory rheumatic disease. Both susceptibility to and clinical manifestations of the disease are highly heritable. Although some genes, notably HLA-B27, have been implicated in susceptibility to the disease, the genetics of the condition are complex and many more genes involved in the condition await discovery.

Impact and interest:

48 citations in Scopus
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39 citations in Web of Science®

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ID Code: 87989
Item Type: Journal Article
Refereed: Yes
Additional Information: No file attached.
Keywords: Ankylosing spondylitis, Association, Genetics, HLA, Linkage, Spondyloarthritis, HLA B27 antigen, HLA B60 antigen, HLA DR antigen, tumor necrosis factor alpha, HLA-DRB1 antigen, article, controlled study, disease severity, familial disease, gene linkage disequilibrium, gene mapping, genetic epidemiology, genetic linkage, genetic risk, genetic susceptibility, heredity, human, immunogenetics, priority journal, rheumatic disease, chromosome map, hospitalization, major histocompatibility complex, pathophysiology, review, Chromosome Mapping, HLA-B27 Antigen, HLA-DR Antigens, Humans, Severity of Illness Index, Spondylitis, Ankylosing
ISSN: 0392-856X
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 01 Oct 2015 23:05
Last Modified: 18 Oct 2015 22:57

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