The genetics of osteoporosis: Future diagnostic possibilities

Brown, M.A. & Eisman, J. A. (2000) The genetics of osteoporosis: Future diagnostic possibilities. Clinics in Laboratory Medicine, 20(3), pp. 527-547.

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Abstract

The risk of developing osteoporosis is determined by the interaction of several mostly unknown genes and environmental factors. Genetic studies in osteoporosis have largely focussed on association studies of a small number of candidate genes, with few linkage studies performed, and large areas of the genome remaining unexplored. Identifying the genes involved in osteoporosis would be a major advance in our understanding of the causation of the disease, and lead to advances in diagnosis, risk prediction, and potentially preventive and therapeutic measures.

Impact and interest:

4 citations in Scopus
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3 citations in Web of Science®

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ID Code: 88000
Item Type: Journal Article
Refereed: Yes
Additional Information: No file attached.
Keywords: environmental factor, gene linkage disequilibrium, gene mapping, genetic linkage, genetic risk, genome, heredity, osteoporosis, phenotype, priority journal, review, risk assessment, Chromosome Mapping, Humans, Linkage (Genetics), Linkage Disequilibrium
ISSN: 0272-2712
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 02 Oct 2015 01:29
Last Modified: 18 Oct 2015 22:58

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