Cohort profile: Andhra Pradesh Children and Parents Study (APCAPS)

Kinra, Sanjay, Radha Krishna, K.V., Kuper, Hannah, Rameshwar Sarma, K.V., Prabhakaran, Poornima, Gupta, Vipin, Kaur Walia, Gagandeep, Bhogadi, Santhi, Kulkarni, Bharati, Kumar, Aniket, Aggarwal, Aastha, Gupta, Ruby, Prabhakaran, Dorairaj, Reddy, K.Srinath, Smith, George Davey, Ben-Shlomo, Yoav, & Ebrahim, Shah (2014) Cohort profile: Andhra Pradesh Children and Parents Study (APCAPS). International Journal of Epidemiology, 43(5), pp. 1417-1424.

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Abstract

The Andhra Pradesh Children and Parents Study (APCAPS) was originally established to study the long-term effects of early-life undernutrition on risk of cardiovascular disease. Its aims were subsequently expanded to include trans-generational influences of other environmental and genetic factors on chronic diseases in rural India. It builds on the Hyderabad Nutrition Trial (HNT) conducted in 1987–90 to compare the effects on birthweight of a protein-calorie supplement for pregnant women and children. The index children of HNT and their mothers were retraced and examined in 2003–05, and the children re-examined as young adults aged 18–21 years in 2009–10. The cohort was expanded to include both parents and siblings of the index children in a recently completed follow-up conducted in 2010–12 (N = ∼6225 out of 10 213 participants). Recruitment of the remaining residents of these 29 villages (N = ∼55 000) in Ranga Reddy district of Andhra Pradesh is now under way. Extensive data on socio-demographic, lifestyle, medical, anthropometric, physiological, vascular and body composition measures, DNA, stored plasma, and assays of lipids and inflammatory markers on APCAPS participants are available. Details of how to access these data are available from the corresponding author.

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ID Code: 88706
Item Type: Journal Article
Refereed: Yes
DOI: 10.1093/ije/dyt128
ISSN: 0300-5771
Divisions: Current > Research Centres > Centre for Health Research
Current > QUT Faculties and Divisions > Faculty of Health
Copyright Owner: Copyright 2013 The Authors
Copyright Statement: This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Deposited On: 01 Nov 2015 23:03
Last Modified: 01 Nov 2015 23:03

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