Prediction of the fate of oxytetracycline and oxolinic acid in a fish pond using simulation model: A preliminary study

Phong, Thai Khanh, Nhung, Dang Thi Tuyet, Hiramatsu, Kazuaki, & Watanabe, Hirozumi (2009) Prediction of the fate of oxytetracycline and oxolinic acid in a fish pond using simulation model: A preliminary study. Journal of the Faculty of Agriculture, 54(2), pp. 513-521.

View at publisher (open access)


The fate of two popular antibiotics, oxytetracycline and oxolinic acid, in a fish pond were simulated using a computational model. The VDC model, which is designed based on a model for predicting pesticide fate and transport in paddy fields, was modified to take into account the differences between the pond and the paddies as well as those between the fish and the rice plant behaviors. The pond conditions were set following the typical practice in South East Asia aquaculture. The two antibiotics were administered to the animal in the pond through medicated feed during a period of 5 days as in actual practice. Concentrations of oxytetracycline in pond water were higher than those of oxolinic acid at the beginning of the simulation. Dissipation rate of oxytetracycline is also higher as it is more readily available for degradation in the water. For the long term, oxolinic acid was present at higher concentration than oxytetracycline in pond water as well as pond sediment. The simulated results were expected to be conservative and can be useful for the lower tier assessment of exposure risk of veterinary medicine in aquaculture industry but more data are needed for the complete validation of the model.

Impact and interest:

3 citations in Scopus
Search Google Scholar™
3 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 88998
Item Type: Journal Article
Refereed: Yes
Keywords: Fate, Model, Risk assessment, VDC, Veterinary medicine
ISSN: 0023-6152
Deposited On: 14 Oct 2015 03:58
Last Modified: 23 Oct 2015 04:51

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page