Genetics of ankylosing spondylitis

Robinson, Philip C. & Brown, Matthew A. (2014) Genetics of ankylosing spondylitis. Molecular Immunology, 57(1), pp. 2-11.

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Ankylosing spondylitis (AS) is a chronic inflammatory arthritis that affects the spine and sacroiliac joints. It causes significant disability and is associated with a number of other features including peripheral arthritis, anterior uveitis, psoriasis and inflammatory bowel disease (IBD). Significant progress has been made in the genetics of AS have in the last five years, leading to new treatments in trial, and major leaps in understanding of the aetiopathogenesis of the disease.

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51 citations in Scopus
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46 citations in Web of Science®

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ID Code: 89068
Item Type: Journal Article
Refereed: Yes
Keywords: Ankylosing spondylitis, Single nucleotide polymorphism association, Spondyloarthritis, aminopeptidase, G protein coupled receptor, HLA B27 antigen, interleukin 1, interleukin 23, major histocompatibility antigen class 1, spacer DNA, allele, arthritis, enteritis, first degree relative, gene, gene linkage disequilibrium, genetic association, genetic screening, human, iridocyclitis, major histocompatibility complex, onset age, pleiotropy, priority journal, psoriasis, recurrence risk, review, risk factor, second degree relative, spondylarthritis, ubiquitination, Aminopeptidases, Genetic Predisposition to Disease, HLA-B27 Antigen, Humans, Inflammatory Bowel Diseases, Interleukin-23, Sacroiliac Joint, Spine, Spondylitis, Ankylosing, Uveitis, Anterior
DOI: 10.1016/j.molimm.2013.06.013
ISSN: 0161-5890
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 15 Oct 2015 02:03
Last Modified: 18 Feb 2016 03:15

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