Visual analytics for large-scale bioinformatic data sets

Smith, Samuel, Hogan, James, Rittenbruch, Markus, Johnson, Daniel, & Brereton, Margot (2015) Visual analytics for large-scale bioinformatic data sets. In 27th Australian Conference on Human-Computer Interaction (OZCHI 2015), 7-10 December 2015, Melbourne, Vic.

Abstract

Rapid advances in sequencing technologies (Next Generation Sequencing or NGS) have led to a vast increase in the quantity of bioinformatics data available, with this increasing scale presenting enormous challenges to researchers seeking to identify complex interactions. This paper is concerned with the domain of transcriptional regulation, and the use of visualisation to identify relationships between specific regulatory proteins (the transcription factors or TFs) and their associated target genes (TGs). We present preliminary work from an ongoing study which aims to determine the effectiveness of different visual representations and large scale displays in supporting discovery. Following an iterative process of implementation and evaluation, representations were tested by potential users in the bioinformatics domain to determine their efficacy, and to understand better the range of ad hoc practices among bioinformatics literate users. Results from two rounds of small scale user studies are considered with initial findings suggesting that bioinformaticians require richly detailed views of TF data, features to compare TF layouts between organisms quickly, and ways to keep track of interesting data points.

Impact and interest:

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ID Code: 89300
Item Type: Conference Paper
Refereed: Yes
Additional URLs:
Keywords: bioinformatics, visualisation, visual encodings, human computer interaction
Subjects: Australian and New Zealand Standard Research Classification > INFORMATION AND COMPUTING SCIENCES (080000) > COMPUTER SOFTWARE (080300) > Bioinformatics Software (080301)
Australian and New Zealand Standard Research Classification > INFORMATION AND COMPUTING SCIENCES (080000) > INFORMATION SYSTEMS (080600) > Computer-Human Interaction (080602)
Divisions: Current > Schools > School of Electrical Engineering & Computer Science
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2015 ACM
Deposited On: 20 Oct 2015 23:57
Last Modified: 18 Dec 2015 22:40

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