Hierarchically structured porous poly(2-oxazoline) hydrogels

Haigh, Jodie N., Chuang, Ya-Mi, Farrugia, Brooke L., Hoogenboom, Richard, Dalton, Paul D., & Dargaville, Tim R. (2016) Hierarchically structured porous poly(2-oxazoline) hydrogels. Macromolecular Rapid Communications, 37(1).

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Abstract

A new method for fabricating hydrogels with intricate control over hierarchical 3D porosity using micro-fiber porogens is presented. Melt electrospinning writing of poly(ε-caprolactone) is used to create the sacrificial template leading to hierarchical structuring consisting of pores inside the denser poly(2-oxazoline) hydrogel mesh. This versatile approach provides new opportunities to create well-defined multilevel control over interconnected pores with diameters in the lower micrometer range inside hydrogels with potential applications as cell scaffolds with tunable diffusion and transport of, e.g. nutrients, growth factors or therapeutics.

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ID Code: 89434
Item Type: Journal Article
Refereed: Yes
Keywords: fibers; hydrogels; melt electrospinning; poly(2-oxazoline)s; porous materials
DOI: 10.1002/marc.201500495
Subjects: Australian and New Zealand Standard Research Classification > CHEMICAL SCIENCE (030000) > MACROMOLECULAR AND MATERIALS CHEMISTRY (030300) > Chemical Characterisation of Materials (030301)
Australian and New Zealand Standard Research Classification > CHEMICAL SCIENCE (030000) > MACROMOLECULAR AND MATERIALS CHEMISTRY (030300) > Synthesis of Materials (030306)
Australian and New Zealand Standard Research Classification > CHEMICAL SCIENCE (030000) > MACROMOLECULAR AND MATERIALS CHEMISTRY (030300) > Macromolecular and Materials Chemistry not elsewhere classified (030399)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Deposited On: 26 Oct 2015 01:55
Last Modified: 07 Mar 2016 11:01

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