Measured and predicted total body water in children with myelomeningocele

Littlewood, R. A., Trocki, O., & Cleghorn, Geoffrey J. (2003) Measured and predicted total body water in children with myelomeningocele. Journal of Paediatrics and Child Health, 39(4), pp. 278-281.

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Objective: Children with myelomeningocele (MMC) have an altered body composition and an atypical distribution of total body water (TBW). The aim of the present study was to determine the accuracy of current predictive equations, based on bioelectrical impedance analysis (BIA), in determining TBW when compared with measured TBW using deuterium dilution. Methods: Fourteen children with MMC were measured for whole body BIA and TBW (using deuterium dilution and the Plateau method). Total body water was predicted using equations based on the resistance and characteristic frequency from BIA measurements and heights of subjects. Results: The mean measured TBW was 15.46 ± 8.28 L and the mean predictions for TBW using equations based on the resistance and characteristic frequency from BIA measurements and heights of subjects were 18.29 ± 8.41 L, 17.72 ± 11.42 L and 12.51 ± 7.59 L, respectively. The best correlation was found using characteristic frequency. The limits of agreement between measured and predicted TBW values using Bland-Altman analysis were large. Conclusions: The present study suggests that the prediction of TBW in children with MMC can be made accurately using the equation of Cornish et al. based on BIA measurements of characteristic frequency.

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6 citations in Scopus
5 citations in Web of Science®
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ID Code: 89503
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By :4
Export Date: 1 September 2015
Correspondence Address: Littlewood, R.A.; Statewide Paediatr. Rehab. Service, Coles Building, Royal Children's Hospital, Herston, QLD 4029, Australia; email:
Keywords: Myelomeningocele, Total body water, deuterium, accuracy, adolescent, article, bioenergy, body composition, body height, calculation, child, clinical article, dilution, female, human, impedance, male, meningomyelocele, priority journal, Body Water, Child, Preschool, Electric Impedance, Humans, Predictive Value of Tests
DOI: 10.1046/j.1440-1754.2003.00137.x
ISSN: 1034-4810
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 04 Nov 2015 01:38
Last Modified: 26 Jun 2017 03:01

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