Genetic studies of disorders of calcium crystal deposition

Timms, A. E., Zhang, Y., Russell, R. G. G., & Brown, M. A. (2002) Genetic studies of disorders of calcium crystal deposition. Rheumatology, 41(7), pp. 725-729.

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In summary, although many factors are likely to be involved in regulating calcification and ossification processes, studies of the causation of articular chondrocalcinosis and disorders of spinal ossification, such as DISH and OPLL, implicate control over inorganic pyrophosphate levels as being one of the most important factors in their aetiopathogenesis. The findings of these studies may prove relevant to other rheumatic diseases in which ectopic ossification occurs, such as AS.

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ID Code: 89549
Item Type: Journal Article
Refereed: Yes
Keywords: pyrophosphate, ankylosing hyperostosis, articular cartilage, calcification, calcinosis, chondrocalcinosis, controlled study, genetics, human, ligament calcinosis, mouse, nonhuman, ossification, pathogenesis, posterior longitudinal ligament, priority journal, review, rheumatic disease, spine disease, Aged, Aged, 80 and over, Calcium Pyrophosphate, Cartilage Diseases, Cartilage, Articular, Crystallization, Female, Genetic Predisposition to Disease, Humans, Male, Middle Aged
DOI: 10.1093/rheumatology/41.7.725
ISSN: 1462-0324
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2002 British Society for Rheumatology
Deposited On: 27 Oct 2015 03:03
Last Modified: 27 Oct 2015 03:03

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