A controlled trial comparing the efficacy of rice-based and hypotonic glucose oral rehydration solutions in infants and young children with gastroenteritis

Wall, C R, Swanson, C E, & Cleghorn, G. J. (1997) A controlled trial comparing the efficacy of rice-based and hypotonic glucose oral rehydration solutions in infants and young children with gastroenteritis. Journal of Gastroenterology And Hepatology, 12(1), pp. 24-28.

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A prospective randomized trial was conducted to compare the efficacy of a rice-based oral rehydration solution (ORS) with glucose ORS in infants and children under 5 years of age with acute diarrhoea and mild to moderate dehydration (<10%). One hundred children presenting to a large metropolitan teaching hospital were eligible for entry to the study and were randomized to receive rice ORS or glucose ORS. Outcome measures were stool output (SO), duration of illness (DD) and recovery time to introduction of other fluids (RTF) and diet (RTD). Significant differences were found for all outcome measures in favour of the rice ORS group. Mean SO was lower (160 vs 213 mt; P<0.02), mean DD was reduced (17.3 vs 24.3 h; P = 0.03) and median RTF was decreased (12.7 vs 18.1 h; P< 0.001) in the rice ORS group compared with the glucose ORS group. The median rime to introduction of diet and mean length of hospital stay showed similar significant reductions. Our study has shown rice ORS to be an acceptable alternative to glucose ORS in young children and have shown that it is significantly more effective in reducing the course of diarrhoeal illness and the time taken to return to normal drinking and eating habits.

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13 citations in Scopus
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10 citations in Web of Science®

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ID Code: 89616
Item Type: Journal Article
Refereed: Yes
Keywords: Gastroenterology & Hepatology, Acute Gastroenteritis, Dehydration, Oral Rehydration Solutions, Electrolyte Solution, Diarrhea, Absorption, Therapy
DOI: 10.1111/j.1440-1746.1997.tb00340.x
ISSN: 0815-9319
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1997 Wiley-Blackwell Publishing Asia
Deposited On: 28 Oct 2015 02:30
Last Modified: 28 Oct 2015 02:30

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