Investigating the potential of Shikonin, a Chinese herbal medicine, as a novel scar remediation therapy

Fan, Chen (2015) Investigating the potential of Shikonin, a Chinese herbal medicine, as a novel scar remediation therapy. PhD thesis, Queensland University of Technology.


This project investigates for the first time the biological mechanisms underlying the anecdotal use of Shikonin, an active component extracted from the Chinese herbal medicine "Zi Cao", as a treatment for hypertrophic scars. Compelling molecular and cellular evidence was generated supporting the therapeutic value of Shikonin as a scar treatment, suggesting that further development of this agent is warranted.

Impact and interest:

1 citations in Web of Science®
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13 since deposited on 15 Dec 2015
7 in the past twelve months

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ID Code: 89688
Item Type: QUT Thesis (PhD)
Supervisor: Upton, Zee, Dong, Ying, & Xie, Yan
Keywords: Shikonin, Hypertrophic scars, Apoptosis, Collagen, Fibroblasts
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Institution: Queensland University of Technology
Deposited On: 15 Dec 2015 01:50
Last Modified: 15 Dec 2015 01:50

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