Early detection of melanoma metastases using microRNAs as novel biomarkers
Stark, Mitchell S. (2015) Early detection of melanoma metastases using microRNAs as novel biomarkers. PhD by Publication, Queensland University of Technology.
Early detection of melanoma skin cancer, prior to metastatic spread, is critical to improve survival outcomes in patients. This study identified a melanoma-related panel of blood markers that can detect the presence of melanoma with high sensitivity and accuracy which is superior to currently used markers for melanoma progression, recurrence, and survival. Overall, the findings discussed in this thesis may lead to more precise measurement of disease progression allowing for better treatments and an increase in overall survival.
Impact and interest:
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|Item Type:||QUT Thesis (PhD by Publication)|
|Supervisor:||Herington, Adrian & Pollock, Pamela|
|Keywords:||Melanoma, miRNA, microRNA, biomarker, progression, resistance, NF1, miR-514a, miR-4731|
|Divisions:||Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Institution:||Queensland University of Technology|
|Deposited On:||12 Apr 2016 06:58|
|Last Modified:||06 May 2016 04:52|
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