Early detection of melanoma metastases using microRNAs as novel biomarkers

Stark, Mitchell S. (2015) Early detection of melanoma metastases using microRNAs as novel biomarkers. PhD by Publication, Queensland University of Technology.

Abstract

Early detection of melanoma skin cancer, prior to metastatic spread, is critical to improve survival outcomes in patients. This study identified a melanoma-related panel of blood markers that can detect the presence of melanoma with high sensitivity and accuracy which is superior to currently used markers for melanoma progression, recurrence, and survival. Overall, the findings discussed in this thesis may lead to more precise measurement of disease progression allowing for better treatments and an increase in overall survival.

Impact and interest:

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52 since deposited on 12 Apr 2016
52 in the past twelve months

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ID Code: 90041
Item Type: QUT Thesis (PhD by Publication)
Supervisor: Herington, Adrian & Pollock, Pamela
Keywords: Melanoma, miRNA, microRNA, biomarker, progression, resistance, NF1, miR-514a, miR-4731
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Institution: Queensland University of Technology
Deposited On: 12 Apr 2016 06:58
Last Modified: 06 May 2016 04:52

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