A follow up MRI-based geometry and computational fluid dynamics study of carotid bifurcation

Zeng, Y. Q. & Li, Z. Y. (2013) A follow up MRI-based geometry and computational fluid dynamics study of carotid bifurcation. In Long, Mian (Ed.) World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China, Springer Berlin Heidelberg, Beijing, China, pp. 172-175.

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Cardiovascular disease is the leading causes of death in the developed world. Wall shear stress (WSS) is associated with the initiation and progression of atherogenesis. This study combined the recent advances in MR imaging and computational fluid dynamics (CFD) and evaluated the patient-specific carotid bifurcation. The patient was followed up for 3 years. The geometry changes (tortuosity, curvature, ICA/CCA area ratios, central to the cross-sectional curvature, maximum stenosis) and the CFD factors (Velocity distribute, Wall Shear Stress (WSS) and Oscillatory Shear Index (OSI)) were compared at different time points.The carotid stenosis was a slight increase in the central to the cross-sectional curvature, and it was minor and variable curvature changes for carotid centerline. The OSI distribution presents ahigh-values in the same region where carotid stenosis and normal border, indicating complex flow and recirculation.The significant geometric changes observed during the follow-up may also cause significant changes in bifurcation hemodynamics.

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ID Code: 90288
Item Type: Conference Paper
Refereed: No
Keywords: Carotid bifurcation, CFD, MRI, Oscillatory Shear Index (OSI), shear stress, Stenosis
DOI: 10.1007/978-3-642-29305-4_47
ISBN: 9783642293054
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2013 Springer-Verlag
Deposited On: 30 Nov 2015 07:31
Last Modified: 04 Dec 2015 01:51

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