MRI-based measurement of carotid mechanical properties in asymptomatic patients

Li, Z. Y. & Gillard, J. H. (2009) MRI-based measurement of carotid mechanical properties in asymptomatic patients. In Proceedings of the ASME Summer Bioengineering Conference-- 2009 : presented at 2009 ASME Summer Bioengineering Conference, June 17-21, 2009, Lake Tahoe, California, USA, American Society of Mechanical Engineers (ASME), Lake Tahoe, USA, pp. 135-136.

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Arterial mechanical property may be a potential variable for risk stratification. Large artery and central arterial compliance have been shown not only to correlate well with overall cardiovascular outcome in large epidemiological studies [1, 2] but also to correlate with coronary atherosclerotic burden as measured by conventional angiography [3]. Until recently, real-time B-mode ultrasound combined with simultaneous blood pressure measurements have been used to assess large artery compliance [4]. These techniques have an excellent temporal resolution but are unable to provide adequate spatial resolution to determine changes in vessel area as opposed to diameter and make the assumption that the vessel is perfectly round. Attempts to use MR imaging to measure large artery compliance have been published previously [5]. However, they have not utilised simultaneous blood pressure measurements during sequence acquisition. We report a technique using regular and simultaneous blood pressure measurement during 2 dimensional phase contrast magnetic resonance imaging 2DPC-MRI to determine local carotid compliance.

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ID Code: 90336
Item Type: Conference Paper
Refereed: No
DOI: 10.1115/SBC2009-205682
ISBN: 9780791848913
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2009 ASME
Deposited On: 30 Nov 2015 05:28
Last Modified: 04 Dec 2015 02:42

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