Discussion of “Generalized estimating equations: Notes on the choice of the working correlation matrix”

Breitung, J., Chaganty, N.R., Daniel, R.M., Kenward, M.G., Lechner, M., Martus, P., Sabo, R.T., Wang, Y-G., & Zorn, C. (2010) Discussion of “Generalized estimating equations: Notes on the choice of the working correlation matrix”. Methods of Information in Medicine, 49(5), pp. 426-432.

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To discuss generalized estimating equations as an extension of generalized linear models by commenting on the paper of Ziegler and Vens "Generalized Estimating Equations. Notes on the Choice of the Working Correlation Matrix".


Inviting an international group of experts to comment on this paper.


Several perspectives have been taken by the discussants. Econometricians have established parallels to the generalized method of moments (GMM). Statisticians discussed model assumptions and the aspect of missing data Applied statisticians; commented on practical aspects in data analysis.


In general, careful modeling correlation is encouraged when considering estimation efficiency and other implications, and a comparison of choosing instruments in GMM and generalized estimating equations, (GEE) would be worthwhile. Some theoretical drawbacks of GEE need to be further addressed and require careful analysis of data This particularly applies to the situation when data are missing at random.

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6 citations in Web of Science®
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ID Code: 90449
Item Type: Journal Article
Refereed: Yes
Keywords: Correlation matrix, generalized estimating equations, independence, estimating equations, restriction of parameter space, moments estimation, longitudinal data, sample properties, linear-models, variables, selection
ISSN: 0026-1270
Divisions: Current > QUT Faculties and Divisions > Science & Engineering Faculty
Deposited On: 17 Nov 2015 04:30
Last Modified: 10 Dec 2015 04:39

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