Pre-operative nutritional support in children with end-stage liver disease accepted for liver transplantation: An approach to management

Chin, S. E., Shepherd, R. W., Cleghorn, G. J., Patrick, M., Ong, T. H., Wilcox, J., Lynch, S., & Strong, R. (1990) Pre-operative nutritional support in children with end-stage liver disease accepted for liver transplantation: An approach to management. Journal Of Gastroenterology And Hepatology, 5(5), pp. 566-572.

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Pre-operative nutritional support was studied in 28 children with end-stage liver disease awaiting orthotopic liver transplantation. Nasogastric supplemental administration of a standard semi-elemental enteral nutritional formula was compared with a similar formula enriched with branched chain amino acids, and with a group receiving oral nutrition only. The duration of treatment in all groups was similar (mean 90 days). Energy intakes in the supplemented groups were 120-150% of recommended daily intakes (RDI), whereas ad libitum intakes in the oral group ranged 58-100% RDI. A significant improvement in mean Z-score for body weight (denoting catch-up) was noted only in those children who received nasogastric supplements enriched with branched-chain amino acids. The standard enterally-fed group maintained their body weight and Z-scores did not change significantly. In contrast, body weight Z-scores in those fed orally declined significantly. Nutritional supportive therapy of malnourished children with end-stage liver disease can minimize or improve nutritional status in children awaiting liver transplantation. The use of nutritional formulae rich in branche-chain amino acids may have nutritional advantages in children with chronic liver disease which require further study and evaluation.

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ID Code: 90549
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By :27
Export Date: 1 September 2015
Keywords: amino acid, adolescent, article, child, clinical article, feeding, human, infant, liver disease, liver transplantation, malnutrition, Amino Acids, Branched-Chain, Biliary Atresia, Energy Intake, Enteral Nutrition, Female, Food, Formulated, Male, Nutrition Disorders, Nutritional Status, Preoperative Care, Support, Non-U.S. Gov't
DOI: 10.1111/j.1440-1746.1990.tb01442.x
ISSN: 0815-9319
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright © John Wiley & Sons, Inc
Deposited On: 19 Nov 2015 02:48
Last Modified: 19 Nov 2015 02:48

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