Development of a novel experimental model to investigate the influence of mechanics on bone healing
Tufekci, Pelin Melisa (2015) Development of a novel experimental model to investigate the influence of mechanics on bone healing. PhD thesis, Queensland University of Technology.
This dissertation proposed a novel experimental model combining a defect configuration with an active instrumented fixation device to investigate the influence of mechanics on bone healing. The proposed defect configuration aimed to minimise physiological loading within an experimental fracture gap and the instrumented fixator was used for the application of controlled displacements and in vivo stiffness monitoring of the healing process. This thesis has provided a novel approach to advance current knowledge and understanding of mechanobiology, which has been limited in previous experimental models.
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|Item Type:||QUT Thesis (PhD)|
|Supervisor:||Epari, Devakar, Steck, Roland, & Glatt, Vaida|
|Keywords:||Fracture healing, Mechanobiology, Ovine model, Mechanical stimulation, External stimulation, Interfragmentary movement, Osteotomy, Animal model|
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Institution:||Queensland University of Technology|
|Deposited On:||11 Jan 2016 05:39|
|Last Modified:||12 Jan 2016 01:51|
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