Osteopenia and rickets in the extremely low birth weight infant: A survey of the incidence and a radiological classification

Masel, J.P., Tudehope, D., Cartwright, D., & Cleghorn, G. (1982) Osteopenia and rickets in the extremely low birth weight infant: A survey of the incidence and a radiological classification. Australasian Radiology, 26(1), pp. 83-96.

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A review was carried out of the radiographs of twenty-five infants with birth weights under 1000 G, who survived for more than twenty-eight days; eighteen of these had enough suitable films for a survey of the progressive bone changes which occur in these infants, including estimation of humeral cortical cross-sectional area. The incidence of the changes has been assessed and a typical progression of radiographic appearances has been shown, with a suggested system of staging. All infants showed some loss of bone mineral, with frank changes of rickets occurring in forty-four percent.

Aetiological factors are mainly concerned with the difficulty of supplying and ensuring absorption of sufficient bone mineral (calcium and phosphate) and vitamin D. Liver immaturity may be another factor. Disease states additional to prematurity accentuate the problem.

Rib fractures occurring around 80–90 days post-nataEy commonly draw attention to the bone disorder and are probably the major clinical factor of importance; there is a high incidence of associated lung disease of uncertain pathology.

Attention is drawn to possible confusion with other bone disorders in the post-natal period.

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ID Code: 90928
Item Type: Journal Article
Refereed: Yes
Keywords: bone, diagnosis, major clinical study, newborn, osteoporosis, prematurity, rickets, skeleton radiography, Australia, Bone Resorption, Female, Human, Infant, Low Birth Weight, Infant, Newborn, Infant, Premature, Diseases, Male
DOI: 10.1111/j.1440-1673.1982.tb02282.x
ISSN: 0004-8461
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Exercise & Nutrition Sciences
Deposited On: 02 Dec 2015 05:24
Last Modified: 15 Dec 2015 22:51

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