Rickets in extremely low birthweight infants

Cleghorn, Geoffrey J., Tudehope, David I., & Masel, John P. (1981) Rickets in extremely low birthweight infants. Australian Paediatric Journal, 17(4), pp. 285-289.

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The effects of increasing the concentration of supplemental vitamin D was studied in two groups of ELBW infants (babies with a birth weight less than 1000 g) during the periods of July 1977 to December 1979 and throughout 1980. There were 21 ELBW infants in the first study period, with 7 infants developing active or stage III rickets. A prospective study of ELBW infants during 1980 revealed 3 infants out of the 12 studied developing active or Stage III rickets. A new radiological classification for rickets of prematurity, Stage I to IV, is presented. Serial serum alkaline phosphatase levels were then compared with these radiological stages and a serial ALP of 5001U/l was found to be statistically significant in the biochemical diagnosis of rickets. As a result of our findings, we suggest that all ELBW would be supplemented with at least 800 IU of vitamin D daily.

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ID Code: 90929
Item Type: Journal Article
Refereed: Yes
Keywords: alkaline phosphatase, ergocalciferol, bone, case report, diagnosis, infant, low birth weight, rickets, skeleton radiography, therapy, Human, Infant, Low Birth Weight, Infant, Newborn, Vitamin D
DOI: 10.1111/j.1440-1754.1981.tb01961.x
ISSN: 0004-993X
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Exercise & Nutrition Sciences
Deposited On: 02 Dec 2015 05:29
Last Modified: 02 Dec 2015 05:29

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