Physostigmine for promethazine poisoning
Cleghorn, Geoffrey & Bourke, Geoffrey (1980) Physostigmine for promethazine poisoning. The Lancet, 2(8190), pp. 368-369.
Experience suggests that the central anticholinergic action of promethazine is a major element in the toxic effects following overdosage. Physostigmine seems to be a direct antidote at doses within the safe therapeutic range; side-effects, if they become a problem, can be treated with intravenous atropine.
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|Item Type:||Journal Article|
|Keywords:||antidote, atropine, imipramine, ipecac, neostigmine, physostigmine, promethazine, adverse drug reaction, ataxia, case report, central nervous system, child, delirium, drug intoxication, hallucination, intoxication, intravenous drug administration, preschool child, school child, slurred speech, therapy, Child, Preschool, Female, Human, Parasympatholytics|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Exercise & Nutrition Sciences
|Deposited On:||02 Dec 2015 04:24|
|Last Modified:||02 Dec 2015 04:24|
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