Physostigmine for promethazine poisoning

Cleghorn, Geoffrey & Bourke, Geoffrey (1980) Physostigmine for promethazine poisoning. The Lancet, 2(8190), pp. 368-369.

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Experience suggests that the central anticholinergic action of promethazine is a major element in the toxic effects following overdosage. Physostigmine seems to be a direct antidote at doses within the safe therapeutic range; side-effects, if they become a problem, can be treated with intravenous atropine.

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7 citations in Scopus
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5 citations in Web of Science®

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ID Code: 90931
Item Type: Journal Article
Refereed: Yes
Keywords: antidote, atropine, imipramine, ipecac, neostigmine, physostigmine, promethazine, adverse drug reaction, ataxia, case report, central nervous system, child, delirium, drug intoxication, hallucination, intoxication, intravenous drug administration, preschool child, school child, slurred speech, therapy, Child, Preschool, Female, Human, Parasympatholytics
DOI: 10.1016/S0140-6736(80)90366-9
ISSN: 0140-6736
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Exercise & Nutrition Sciences
Deposited On: 02 Dec 2015 04:24
Last Modified: 02 Dec 2015 04:24

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