Do bacteria differentiate between degrees of nanoscale surface roughness?
Bazaka, Kateryna, Crawford, Russell J., & Ivanova, Elena P. (2011) Do bacteria differentiate between degrees of nanoscale surface roughness? Biotechnology Journal, 6(9), pp. 1103-1114.
Whereas the employment of nanotechnology in electronics and optics engineering is relatively well established, the use of nanostructured materials in medicine and biology is undoubtedly novel. Certain nanoscale surface phenomena are being exploited to promote or prevent the attachment of living cells. However, as yet, it has not been possible to develop methods that completely prevent cells from attaching to solid surfaces, since the mechanisms by which living cells interact with the nanoscale surface characteristics of these substrates are still poorly understood. Recently, novel and advanced surface characterisation techniques have been developed that allow the precise molecular and atomic scale characterisation of both living cells and the solid surfaces to which they attach. Given this additional capability, it may now be possible to define boundaries, or minimum dimensions, at which a surface feature can exert influence over an attaching living organism.This review explores the current research on the interaction of living cells with both native and nanostructured surfaces, and the role that these surface properties play in the different stages of cell attachment.
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|Item Type:||Journal Article|
|Keywords:||bacterial adhesion, bacterial attachment, nanoarchitecture, nanobiotechnology, nanoroughness|
|Subjects:||Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > MATERIALS ENGINEERING (091200)|
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim|
|Deposited On:||20 Jan 2016 03:05|
|Last Modified:||21 Jan 2016 04:52|
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