On the probability of dizygotic twins being concordant for two alleles at multiple polymorphic loci

Nyholt, D.R. (2006) On the probability of dizygotic twins being concordant for two alleles at multiple polymorphic loci. Twin Research and Human Genetics, 9(2), pp. 194-197.

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Accurate determination of same-sex twin zygosity is important for medical, scientific and personal reasons. Determination may be based upon questionnaire data, blood group, enzyme isoforms and fetal membrane examination, but assignment of zygosity must ultimately be confirmed by genotypic data. Here methods are reviewed for calculating average probabilities of correctly concluding a twin pair is monozygotic, given they share the same genotypes across all loci for commonly utilized multiplex short tandem repeat (STR) kits.

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ID Code: 92153
Item Type: Journal Article
Refereed: Yes
Additional Information: Nyholt, Dale R
Research Support, Non-U.S. Gov't
2006/04/14 09:00
Twin Res Hum Genet. 2006 Apr;9(2):194-7.
Keywords: *Alleles, Female, Genotype, Humans, Internet, Male, *Models, Genetic, *Polymorphism, Genetic, Probability, Quantitative Trait Loci/*genetics, Tandem Repeat Sequences/*genetics, Twins, Dizygotic/*genetics
DOI: 10.1375/183242706776382383
ISSN: 1832-4274
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright © Cambridge University Press 2006
Deposited On: 22 Jan 2016 01:44
Last Modified: 08 Feb 2016 23:37

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