Development of immunotherapies and vaccines against visceral leishmaiasis
Faleiro, Rebecca Jacinto (2016) Development of immunotherapies and vaccines against visceral leishmaiasis. PhD thesis, Queensland University of Technology.
Visceral leishmaniasis (VL) is a chronic parasitic disease prevalent in tropical and sub- tropical countries. This study focused on the development of immune-based therapy with immune checkpoint inhibitors and/or activators, as well as cytokines as a way to treat VL either alone or in combination with conventional drugs. Since many chronic infectious diseases share mechanisms of immune suppression, these findings have broader implications for other infectious diseases, such as HIV, tuberculosis and malaria.
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|Item Type:||QUT Thesis (PhD)|
|Supervisor:||Hafner, Louise & Huston, Willa|
|Keywords:||CD4+ T cells, Leishmania, Visceral leishmaniasis, Immunetherapy, Vaccines|
|Divisions:||Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Institution:||Queensland University of Technology|
|Deposited On:||31 Mar 2016 00:37|
|Last Modified:||31 Mar 2016 00:37|
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