Monitoring exposure to polycyclic aromatic hydrocarbons in an Australian population using pooled urine samples

Thai, Phong K., Heffernan, Amy, Toms, Leisa-Maree, Li, Zheng, Calafat, Antonia, Hobson, Peter, Broomhall, Sara, & Mueller, Jochen F. (2016) Monitoring exposure to polycyclic aromatic hydrocarbons in an Australian population using pooled urine samples. Environment International, 88, pp. 30-35.

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Abstract

Integrated exposure to polycyclic aromatic hydrocarbons (PAHs) can be assessed through monitoring of urinary mono-hydroxylated PAHs (OH-PAHs). The aim of this study was to provide the first assessment of exposure to PAHs in a large sample of the population in Queensland, Australia including exposure to infant (0-4. years). De-identified urine specimens, obtained from a pathology laboratory, were stratified by age and sex, and pooled (n. =. 24 pools of 100) and OH-PAHs were measured by gas chromatography-isotope dilution-tandem mass spectrometry. Geometric mean (GM) concentrations ranged from 30. ng/L (4-hydroxyphenanthrene) to 9221. ng/L (1-naphthol). GM of 1-hydroxypyrene, the most commonly used PAH exposure biomarker, was 142. ng/L. The concentrations of OH-PAHs found in this study are consistent with those in developed countries and lower than those in developing countries. We observed no association between sex and OH-PAH concentrations. However, we observed lower urinary concentrations of all OH-PAHs in samples from infants (0-4. years), children (5-14. years) and the elderly (>. 60. year old) compared with samples from other age groups (15-29, 30-44 and 45-59. years) which may be attributed to age-dependent behaviour-specific exposure sources.

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ID Code: 92423
Item Type: Journal Article
Refereed: Yes
Keywords: biomonitoring, exposure monitoring, infant, OH-PAHs, urinary metabolite
DOI: 10.1016/j.envint.2015.11.019
ISSN: 0160-4120
Subjects: Australian and New Zealand Standard Research Classification > ENVIRONMENTAL SCIENCES (050000) > ENVIRONMENTAL SCIENCE AND MANAGEMENT (050200) > Environmental Monitoring (050206)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > PUBLIC HEALTH AND HEALTH SERVICES (111700) > Public Health and Health Services not elsewhere classified (111799)
Australian and New Zealand Standard Research Classification
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Current > Schools > School of Public Health & Social Work
Funding:
Copyright Owner: Copyright 2016 Elsevier
Deposited On: 29 Jan 2016 01:14
Last Modified: 01 Feb 2016 03:53

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