Ambient temperature and risk of cardiovascular hospitalization: An updated systematic review and meta-analysis

Phung, Dung, Thai, Phong K., Guo, Yuming, Morawska, Lidia, Rutherford, Shannon, & Chu, Cordia (2016) Ambient temperature and risk of cardiovascular hospitalization: An updated systematic review and meta-analysis. Science of the Total Environment, 550, pp. 1084-1102.

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The association between temperatures and risk of cardiovascular mortality has been recognized but the association drawn from previous meta-analysis was weak due to the lack of sufficient studies. This paper presented a review with updated reports in the literature about the risk of cardiovascular hospitalization in relation to different temperature exposures and examined the dose–response relationship of temperature-cardiovascular hospitalization by change in units of temperature, latitudes, and lag days. The pooled effect sizes were calculated for cold, heat, heatwave, and diurnal variation using random-effects meta-analysis, and the dose–response relationship of temperature-cardiovascular admission was modelled using random-effect meta-regression. The Cochrane Q-test and index of heterogeneity (I2) were used to evaluate heterogeneity, and Egger's test was used to evaluate publication bias. Sixty-four studies were included in meta-analysis. The pooled results suggest that for a change in temperature condition, the risk of cardiovascular hospitalization increased 2.8% (RR, 1.028; 95% CI, 1.021–1.035) for cold exposure, 2.2% (RR, 1.022; 95% CI, 1.006–1.039) for heatwave exposure, and 0.7% (RR, 1.007; 95% CI, 1.002–1.012) for an increase in diurnal temperature. However no association was observed for heat exposure. The significant dose–response relationship of temperature — cardiovascular admission was found with cold exposure and diurnal temperature. Increase in one-day lag caused a marginal reduction in risk of cardiovascular hospitalizations for cold exposure and diurnal variation, and increase in latitude was associated with a decrease in risk of cardiovascular hospitalizations for diurnal temperature only. There is a significant short-term effect of cold exposure, heatwave and diurnal variation on cardiovascular hospitalizations. Further research is needed to understand the temperature-cardiovascular relationship for different climate areas.

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12 citations in Web of Science®
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ID Code: 93135
Item Type: Journal Article
Refereed: Yes
Keywords: Temperature exposure, Cold exposure, Heatwave, Diurnal temperature, Cardiovascular admission
DOI: 10.1016/j.scitotenv.2016.01.154
ISSN: 0048-9697
Divisions: Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2016 Elsevier
Copyright Statement: Licensed under the Creative Commons Attribution; Non-Commercial; No-Derivatives 4.0 International. DOI: 10.1016/j.scitotenv.2016.01.154
Deposited On: 22 Feb 2016 23:39
Last Modified: 27 Jun 2017 03:01

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