The dopamine-mediation of perception hypothesis and the implications for schizophrenia
Golembiewski, Jan A. (2010) The dopamine-mediation of perception hypothesis and the implications for schizophrenia. In Carr, Vaughan (Ed.) 11th Australasian Schizophrenia Conference: Molecules to Mind, 22-24 September 2010, Sydney, N.S.W.
Following Kapur’s hypothesis  that schizophrenia is the intensification of phenomenological experience caused by the upregulation of dopamine, a survey of observed dopamine responses to phenomenal information was conducted.
An integrative study.
When considered in the light of the ecological theory of perception (ETP)  and global workspace theory (GBT)  Kapur’s hypothesis makes sense: Both the ETP and the GBT require an agent to attribute salience to perceptual information in order to filter an infinite array of available information and usefully sort information by importance. Dopamine may be the primary agent for this purpose. Thus perception itself is suspected as being a dopamine-mediated, and the symptoms and signs of schizophrenia may therefore be the result of dopamine dysfunction.
The application of both ETP and GBT to the dopamine hypothesis gives the hypothesis a much-needed causal mechanism and the confl uence of these theories also provides ETP with a neurological perceptual fi lter. This paper provides a compelling model for schizophrenia; a hypothesis that ties perceptual theory to Kapur ’ s concept of dopamine-mediated salience.
Impact and interest:
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|Item Type:||Conference Item (Poster)|
|Divisions:||Current > Schools > School of Design
Current > QUT Faculties and Divisions > Creative Industries Faculty
|Deposited On:||24 Feb 2016 00:56|
|Last Modified:||24 Feb 2016 00:56|
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