Cost-effectiveness of a nonpharmacological intervention in pediatric burn care

Brown, Nadia J., David, Michael, Cuttle, Leila, Kimble, Roy M., Higashi, Hideki, & Rodger, Sylvia (2015) Cost-effectiveness of a nonpharmacological intervention in pediatric burn care. Value in Health, 18(5), pp. 631-637.

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To report the cost-effectiveness of a tailored handheld computerized procedural preparation and distraction intervention (Ditto) used during pediatric burn wound care in comparison to standard practice.


An economic evaluation was performed alongside a randomized controlled trial of 75 children aged 4 to 13 years who presented with a burn to the Royal Children's Hospital, Brisbane, Australia. Participants were randomized to either the Ditto intervention (n = 35) or standard practice (n = 40) to measure the effect of the intervention on days taken for burns to re-epithelialize. Direct medical, direct nonmedical, and indirect cost data during burn re-epithelialization were extracted from the randomized controlled trial data and combined with scar management cost data obtained retrospectively from medical charts. Nonparametric bootstrapping was used to estimate statistical uncertainty in cost and effect differences and cost-effectiveness ratios.


On average, the Ditto intervention reduced the time to re-epithelialize by 3 days at AU$194 less cost for each patient compared with standard practice. The incremental cost-effectiveness plane showed that 78% of the simulated results were within the more effective and less costly quadrant and 22% were in the more effective and more costly quadrant, suggesting a 78% probability that the Ditto intervention dominates standard practice (i.e., cost-saving). At a willingness-to-pay threshold of AU$120, there is a 95% probability that the Ditto intervention is cost-effective (or cost-saving) against standard care.


This economic evaluation showed the Ditto intervention to be highly cost-effective against standard practice at a minimal cost for the significant benefits gained, supporting the implementation of the Ditto intervention during burn wound care.

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ID Code: 93549
Item Type: Journal Article
Refereed: Yes
Keywords: burns, child, cost-effectiveness, economic evaluation, nonpharmacological intervention, randomized controlled trial, re-epithelialization
DOI: 10.1016/j.jval.2015.04.011
ISSN: 1524-4733
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Deposited On: 08 Mar 2016 02:00
Last Modified: 08 Mar 2016 21:25

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