Prostate cancer organoids: A potential new tool for testing drug sensitivity
Vela, Ian & Chen, Yu (2015) Prostate cancer organoids: A potential new tool for testing drug sensitivity. Expert Review of Anticancer Therapy, 15(3), pp. 261-263.
Recent technical advances have enabled for the first time, reliable in vitro culture of prostate cancer samples as prostate cancer organoids. This breakthrough provides the significant possibility of high throughput drug screening covering the spectrum of prostate cancer phenotypes seen clinically. These advances will enable precision medicine to become a reality, allowing patient samples to be screened for effective therapeutics ex vivo, with tailoring of treatments specific to that individual. This will hopefully lead to enhanced clinical outcomes, avoid morbidity due to ineffective therapies and improve the quality of life in men with advanced prostate cancer.
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