YB-1, a key regulator of androgen receptor signalling

Rockstroh, Anja, Pokorny, Morgan R., Lehman, Melanie, Walker, Chelsea, & Nelson, Colleen (2015) YB-1, a key regulator of androgen receptor signalling. In 2nd Prostate Cancer World Congress, 17-21 August 2015, Cairns Convention Centre, Cairns, Qld.

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Reactivation of androgen receptor signalling is one of the hallmarks of prostate cancer progression to the terminal castrate resistant stage. A better understanding of mechanisms driving this adaptive response is essential for the development of innovative intervention strategies that effectively delay or halt prostate cancer progression. The Y-box binding protein 1 (YB-1) has been found to be closely associated with prostate cancer progression. By characterising its role in the adaptive process leading to castrate resistance, we aim to promote YB-1 as a novel therapeutic target in advanced prostate cancer.

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ID Code: 94838
Item Type: Conference Item (Other)
Refereed: Yes
Keywords: YB-1, regulator, androgen receptor signalling, prostate cancer
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > ONCOLOGY AND CARCINOGENESIS (111200) > Cancer Cell Biology (111201)
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2015 The Author(s)
Deposited On: 14 Apr 2016 23:56
Last Modified: 17 Apr 2016 04:05

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