YB-1, a key regulator of androgen receptor signalling
Rockstroh, Anja, Pokorny, Morgan R., Lehman, Melanie, Walker, Chelsea, & Nelson, Colleen (2015) YB-1, a key regulator of androgen receptor signalling. In 2nd Prostate Cancer World Congress, 17-21 August 2015, Cairns Convention Centre, Cairns, Qld.
Reactivation of androgen receptor signalling is one of the hallmarks of prostate cancer progression to the terminal castrate resistant stage. A better understanding of mechanisms driving this adaptive response is essential for the development of innovative intervention strategies that effectively delay or halt prostate cancer progression. The Y-box binding protein 1 (YB-1) has been found to be closely associated with prostate cancer progression. By characterising its role in the adaptive process leading to castrate resistance, we aim to promote YB-1 as a novel therapeutic target in advanced prostate cancer.
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|Item Type:||Conference Item (Other)|
|Keywords:||YB-1, regulator, androgen receptor signalling, prostate cancer|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > ONCOLOGY AND CARCINOGENESIS (111200) > Cancer Cell Biology (111201)|
|Divisions:||Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 2015 The Author(s)|
|Deposited On:||14 Apr 2016 23:56|
|Last Modified:||17 Apr 2016 04:05|
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