Chlamydial infertility in women: Diagnosis, epidemiology and immune response

Menon, Shruti (2016) Chlamydial infertility in women: Diagnosis, epidemiology and immune response. PhD thesis, Queensland University of Technology.


This project primarily focused on the development of a novel, non-invasive peptide-based ELISA to diagnose C. trachomatis-related infertility in women. In this study, an in silico approach was applied to identify and design novel peptide antigens that are specific to women with C. trachomatis-related infertility. The serological assay was developed such that it could potentially replace invasive techniques for early infertility investigation. The thesis further investigated the sero-prevalence of chlamydial infertility in women from a low-resource, high prevalence setting. In addition, the thesis also identified immune markers that were associated with the C. trachomatis-related infertility in women.

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40 since deposited on 28 Apr 2016
40 in the past twelve months

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ID Code: 94934
Item Type: QUT Thesis (PhD)
Supervisor: Huston, Willa, Timms, Peter, & Alexander, Kimberly
Keywords: C. trachomatis, Female Infertility, Sequelae, Immunopathogenesis, Sero-epidemiology, Serological diagnosis, Cytokines, Samoa
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Institution: Queensland University of Technology
Deposited On: 28 Apr 2016 23:58
Last Modified: 28 Apr 2016 23:58

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