Synthesis of novel dual acting cardio-protective agents

Mankar, Viraj (2016) Synthesis of novel dual acting cardio-protective agents. PhD thesis, Queensland University of Technology.

Abstract

This research designed and synthesised novel dual action cardio-protective agents combining with nitroxides possessing antioxidant properties. The work resulted in the discovery of a new generation of chemical compounds which can act on more than one targeted disease. This new generation multi-targeted drug compounds can have benefits in reducing toxicity and side effects. The synthesised drug compounds could potentially act as effective preventive treatments for inflammatory diseases and also provide cardiovascular protection.

Impact and interest:

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32 since deposited on 23 May 2016
32 in the past twelve months

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ID Code: 95466
Item Type: QUT Thesis (PhD)
Supervisor: Bottle, Steven & Fairfull-Smith, Kathryn
Keywords: Adenosine, Adenosine Receptors, Cardio-protection, Nitroxides, Novel Dual Acting drugs, Oxidative stress, Ischaemia-reperfusion Injury, Antioxidants, Free Radicals, Synthesis
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Institution: Queensland University of Technology
Deposited On: 23 May 2016 23:47
Last Modified: 23 May 2016 23:47

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