Oxygen cost of ventilation and its effect on the VO 2 plateau

Marks, D.W., Robergs, R.A., Nelson, J., Vella, C., Bell-Wilson, J., & Apkarian, M. (2005) Oxygen cost of ventilation and its effect on the VO 2 plateau. Journal of Exercise Physiology Online, 8(5), pp. 1-13.

View at publisher


Evidence of significant oxygen requirements for ventilation during moderate to intense exercise prompted the investigation into whether the oxygen cost of ventilation effects the presence of the VO 2 plateau. The purpose was to compare whole-body VO 2 (wb-VO 2) to locomotor-muscle VO 2 VO 2LOC; calculated by subtracting the VO 2 of the muscles used to ventilate during exercise (VO 2RM) from wb-VO 2 during maximal exercise for the presence of the VO 2-plateau. Twenty-two subjects performed a VO 2max test on a cycle ergometer to determine the range of V E for each subject. On a separate occasion, the VO 2RM was measured at nine different V E using isocapnic hyperpnea trails. Maximal VO 2RM equaled 18.1±4.4% of wb-VO 2max. VO 2RM increased exponentially with increasing V E. The increase in wb-VO 2 during maximal exercise was greater than that for wb-VO 2 when compared to VO 2LOC (p < 0.05), and therefore the incidence of a VO 2 plateau was greater for VO 2LOC (15 of 22 subjects) when compared to wb-VO 2 (1 of 22 subjects, p < 0.05). The VO 2RM significantly reduces the wb-VO 2 slope during maximal exercise, and can be accurately predicted based on the regression equation {VO 2RM (mL/min) = 346.9 0.007614 x VE (L/min)}. The data indicate that the use of wb-VO 2 to model and understand body and muscle energetics during exercise can be questioned. Correcting wb-VO 2 for the VO 2RM provides a more valid representation of the oxygen uptake kinetics of the exercising muscles.

Impact and interest:

2 citations in Scopus
Search Google Scholar™

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 96853
Item Type: Journal Article
Refereed: Yes
Additional Information: cited By 2
Keywords: Hyperventilation; Incremental Exercise; Maximal Exercise; Maximal Oxygen Uptake; Plateau; Work of Breathing
ISSN: 1097-9751
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Schools > School of Exercise & Nutrition Sciences
Copyright Owner: Copyright © 2016 Elsevier B.V 2005
Deposited On: 28 Jul 2016 00:39
Last Modified: 28 Jul 2016 00:39

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page