A comparison of four techniques to measure anterior and posterior vertebral body heights and sagittal plane wedge angles in adolescent idiopathic scoliosis
Newell, Nicolas, Grant, Caroline A., Keenan, Bethany E., Izatt, Maree T., Pearcy, Mark J., & Adam, Clayton J. (2016) A comparison of four techniques to measure anterior and posterior vertebral body heights and sagittal plane wedge angles in adolescent idiopathic scoliosis. Medical & Biological Engineering & Computing. (In Press)
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Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional (3D) spinal deformity of unknown aetiology. Increased growth of the anterior part of the vertebrae known as anterior overgrowth has been proposed as a potential driver for AIS initiation and progression. To date, there has been no objective evaluation of the 3D measurement techniques used to identify this phenomenon and the majority of previous studies use 2D planar assessments which contain inherent projection errors due to the vertebral rotation which is part of the AIS deformity. In this study, vertebral body heights and wedge angles were measured in a test group of AIS patients and healthy controls using four different image analysis and measurement techniques. Significant differences were seen between the techniques in terms of vertebral body (VB) heights and VB wedge angles. The low variability, and the fact that the rotation and tilt of the deformed VBs are taken into account suggests that the proposed technique using the full 3D orientation of the vertebrae is the most reliable method to measure anterior and posterior VB heights and sagittal plane wedge angles in 3D image datasets. These results have relevance for future investigations that aim to quantify anterior overgrowth in AIS patients for comparison with healthy controls.
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|Item Type:||Journal Article|
|Keywords:||anterior overgrowth, adolescent idiopathic scoliosis, AIS, magnetic resonance imaging, MRI, spine deformity, vertebral body|
|Subjects:||Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Orthopaedics (110314)
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 2016 Springer|
|Deposited On:||19 Jul 2016 23:51|
|Last Modified:||24 Jul 2016 04:08|
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