Impact of contact lens wear on conjunctival goblet cells
Holguin Colorado, Luisa Fernanda (2016) Impact of contact lens wear on conjunctival goblet cells. PhD thesis, Queensland University of Technology.
Up to fifty percent of contact lens wearers discontinue from lens wear as a result of symptoms of dry eye. Using a high power confocal microscope specially adapted for examining the eye, the candidate observed that contact lens wear is associated with a reduction in the number of mucus-secreting conjunctival goblet cells, which means that the eye is less well lubricated, leading to discomfort during blinking. This discovery may pave the way towards developing strategies to avoid lens-induced discomfort, leading to more satisfied patients and saving the contact lens industry hundreds of millions of dollars each year.
Impact and interest:
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|Item Type:||QUT Thesis (PhD)|
|Supervisor:||Efron, Nathan & Pritchard, Nicola|
|Keywords:||goblet cells, contact lens, impression cytology, confocal microscopy, conjunctiva|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Optometry & Vision Science
|Institution:||Queensland University of Technology|
|Deposited On:||06 Sep 2016 00:44|
|Last Modified:||06 Sep 2016 00:44|
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