On the evolution and molecular epidemiology of the potyvirus Papaya ringspot virus

Bateson, Marion F., Lines, Rosemarie E., Revill, Peter A., Chaleeprom, Worawan, Ha, Cuong V., Gibbs, Adrian J., & Dale, James L. (2002) On the evolution and molecular epidemiology of the potyvirus Papaya ringspot virus. Journal of General Virology, 83(10), pp. 2575-2585.


The potyvirus Papaya ringspot virus (PRSV) is found throughout the tropics and subtropics. Its P biotype is a devastating pathogen of papaya crops and its W biotype of cucurbits. PRSV-P is thought to arise by mutation from PRSV-W. However, the relative impact of mutation and movement on the structure of PRSV populations is not well characterized. To investigate this, we have determined the coat protein sequences of isolates of both biotypes of PRSV from Vietnam (50), Thailand (13), India (1) and the Philippines (1), and analysed them together with 28 PRSV sequences already published, so that we can better understand the molecular epidemiology and evolution of PRSV. In Thailand, variation was greater among PRSV-W isolates (mean nucleotide divergence 7·6%) than PRSV-P isolates (mean 2·6%), but in Vietnamese populations the P and W biotypes were more but similarly diverse. Phylogenetic analyses of PRSV also involving its closest known relative, Moroccan watermelon mosaic virus, indicate that PRSV may have originated in Asia, particularly in the Indian subcontinent, as PRSV populations there are most diverse and hence have probably been present longest. Our analyses show that mutation, together with local and long-distance movement, contributes to population variation, and also confirms an earlier conclusion that populations of the PRSV-P biotype have evolved on several occasions from PRSV-W populations.

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70 citations in Scopus
69 citations in Web of Science®
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ID Code: 9912
Item Type: Journal Article
Refereed: Yes
Additional Information: For more information, please refer to the journal’s website (see hypertext link) or contact the author.
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ISSN: 0022-1317
Divisions: Current > Research Centres > Centre for Tropical Crops and Biocommodities
Past > QUT Faculties & Divisions > Faculty of Science and Technology
Past > Schools > School of Life Sciences
Past > Schools > School of Physical & Chemical Sciences
Copyright Owner: Copyright 2002 Society for General Microbiology
Deposited On: 03 Oct 2007 00:00
Last Modified: 21 Apr 2010 16:56

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