Using the reversible addition-fragmentation chain transfer process to synthesize core-crosslinked micelles

Zhang, L., Katapodi, K., Davis, T. P., Barner-Kowollik, C., & Stenzel, M. H. (2006) Using the reversible addition-fragmentation chain transfer process to synthesize core-crosslinked micelles. Journal of Polymer Science, Part A: Polymer Chemistry, 44(7).

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Abstract

Poly(2-hydroxyethyl acrylate)-poly(n-butyl acrylate) block copolymers were synthesized with the reversible addition-fragmentation chain transfer (RAFT) process. The block copolymers were synthesized successfully with either poly(2-hydroxyethyl acrylate) or poly(n-butyl acrylate) macro-RAFT agents. The resulting block copolymers had narrow molecular weight distributions (polydispersity index = 1.3-1.4). Copolymer self-aggregation in water yielded micelles, with the hydrodynamic diameter (Dh) values of the aggregates dependent on the length of both blocks according to Dh - NBA 1.17NHEA 0.57, where N BA is the number of repeating units of n-butyl acrylate and N HEA is the number of repeating units of 2-hydroxyethyl acrylate. The micelles were subsequently stabilized via chain extension of the block copolymer with a crosslinking agent. The successful chain extension in a micellar system was confirmed by an increase in the molecular weight, which was detected with membrane osmometry. The crosslinked particles showed noticeably different aggregation behavior in diverse solvent systems. The uncrosslinked micelles formed by the block copolymer (NHEA = 260, NBA = 75) displayed a definite critical micelle concentration at 5.4 × 10 -4 g L-1 in aqueous solutions. However, upon crosslinking, the critical micelle concentration transition became obscure. © 2006 Wiley Periodicals, Inc.

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ID Code: 99139
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By :59
Export Date: 5 September 2016
CODEN: JPACE
Correspondence Address: Stenzel, M.H.; Centre for Advanced Macromolecular Design, School of Chemical Engineering and Industrial Chemistry, University of New South Wales, Sydney, NSW 2052, Australia; email: camd@unsw.edu.au
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Keywords: Block copolymers, Crosslinking, Micelles, Reversible addition fragmentation chain transfer (RAFT), Concentration (process), Hydrodynamics, Molecular weight, Osmosis, Polyesters, Solutions, Core-crosslinked micelles, Membrane osmometry, Narrow molecular weight distributions
DOI: 10.1002/pola.21328
ISSN: 0887624X
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute for Future Environments
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Deposited On: 22 Sep 2016 04:50
Last Modified: 05 Oct 2016 05:48

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