RAFT chemistry and huisgen 1,3-dipolar cycloaddition: A route to block copolymers of vinyl acetate and 6-O-methacryloyl mannose?

Ting, S. R. S., Granville, A. M., Quémener, D., Davis, T. P., Stenzel, M. H., & Barner-Kowollik, C. (2007) RAFT chemistry and huisgen 1,3-dipolar cycloaddition: A route to block copolymers of vinyl acetate and 6-O-methacryloyl mannose? Australian Journal of Chemistry, 60(6).

View at publisher

Abstract

The present communication explores a novel avenue to glycopolymer-block- poly(vinyl acetate) polymers by a combination of reversible addition fragmentation chain transfer (RAFT) chemistry and Huisgen 1,3-dipolar cycloaddition (i.e., so-called ?click' chemistry) under mild reaction conditions. Such block copolymers are?because of the strongly disparate reactivity of the two monomers?otherwise not obtainable. Poly(vinyl acetate) that has an azide end group (Mn 6800 g mol?1, PDI 1.15) was treated with poly(6-O-methacryloyl mannose) (Mn 7600 g mol ?1, PDI 1.11) in the presence of 1,8-diaza[5,4,0]bicycloundec-7-ene and copper(i) iodide. The resulting poly(vinyl acetate)-block-poly(6-O- methacryloyl mannose) had a number-average molecular weight of 15 400 g mol ?1 and a PDI of 1.48, which indicates that while the cycloaddition had occurred the resulting polymer distribution featured a considerable width. The resulting slightly amphiphilic block copolymer was subsequently investigated with regard to its self-assembly in aqueous solution. Dynamic light scattering studies indicated a hydrodynamic diameter of close to 200 nm. Transmission electron microscopy studies indicate the formation of rods as well as spheres with transitions between these two phases. However, the segregation between core and shell in the spheres is not pronounced; such behaviour is expected for weakly amphiphilic block copolymers. © CSIRO 2007.

Impact and interest:

74 citations in Scopus
66 citations in Web of Science®
Search Google Scholar™

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 99162
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By :71
Export Date: 5 September 2016
CODEN: AJCHA
Correspondence Address: Barner-Kowollik, C.; Centre for Advanced Macromolecular Design, School of Chemical Sciences and Engineering, University of New South Wales, Sydney, NSW 2052, Australia; email: camd@unsw.edu.au
Keywords: Block copolymers, Hydrodynamics, Molecular weight, Monomers, Polyvinyl acetates, Self assembly, Amphiphilic block copolymers, Poly(6-O-methacryloyl mannose), Reversible addition fragmentation chain transfer (RAFT), Cycloaddition
DOI: 10.1071/CH07089
ISSN: 00049425
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute for Future Environments
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Deposited On: 22 Sep 2016 04:50
Last Modified: 02 May 2017 23:24

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page