Simultaneous reversible addition fragmentation chain transfer and ring-opening polymerization

Le Hellaye, M., Lefay, C., Davis, T. P., Stenzel, M. H., & Barner-Kowollik, C. (2008) Simultaneous reversible addition fragmentation chain transfer and ring-opening polymerization. Journal of Polymer Science, Part A: Polymer Chemistry, 46(9).

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The simultaneous ring-opening polymerization (ROP) of ε-caprolactone (ε-CL) and 2-hydroxyethyl methacrylate (HEMA) polymerization via reversible addition fragmentation chain transfer (RAFT) chemistry and the possible access to graft copolymers with degradable and nondegradable segments is investigated. HEMA and ε-CL are reacted in the presence of cyanoisopropyl dithiobenzoate (CPDB) and tin(II) 2-ethylhexanoate (Sn(Oct)2) under typical ROP conditions (T > 100°C) using toluene as the solvent in order to lead to the graft copolymer PHEMA-g-PCL. Graft copolymer formation is evidenced by a combination of size-exclusion chromatography (SEC) and NMR analyses as well as confirmed by the hydrolysis of the PCL segments of the copolymer. With targeted copolymers containing at least 10% weight of PHEMA and relatively small PHEMA backbones (ca. 5,000-10,000 g mol-1) the copolymer grafting density is higher than 90%. The ratio of free HEMA-PCL homopolymer produced during the "one-step" process was found to depend on the HEMA concentration, as well as the half-life time of the radical initiator used. © 2008 Wiley Periodicals, Inc.

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ID Code: 99188
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By :28
Export Date: 5 September 2016
Correspondence Address: Barner-Kowollik, C.; Centre for Advanced Macromolecular Design (CAMD), School of Chemical Sciences and Engineering, University of New South Wales, Sydney, NSW 2052, Australia; email:
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Keywords: ε-caprolactone, 2-hydroxyethyl methacrylate (HEMA), NMR, One-step synthesis, Reversible addition fragmentation chain transfer (RAFT), Ring-opening polymerization (ROP), Hydrolysis, Nuclear magnetic resonance spectroscopy, Ring opening polymerization, Size exclusion chromatography, Toluene, Copolymer grafting density, Graft copolymer formation, Copolymers
DOI: 10.1002/pola.22647
ISSN: 0887624X
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute for Future Environments
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Deposited On: 22 Sep 2016 04:50
Last Modified: 10 Oct 2016 04:11

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