On the quantitative click conjugation of molecular weight distributions: what can theoretically be expected?

Barner-Kowollik, C. (2009) On the quantitative click conjugation of molecular weight distributions: what can theoretically be expected? Macromolecular Rapid Communications, 30(19).

View at publisher


The assessment of the success of a click conjugation for block copolymer formation often occurs via ill-defined criteria based on the qualitative shape of the size exclusion chromatography (SEC) distribution as well as unsuitable characteristics of these molecular weight distributions such as the peak molecular weight, Mp. The data presented herein illustrate that from the shape of the SEC distribution, w(log M) versus log M, of the click product -under the assumption of a 100% efficient conjugation reaction -a conclusion about the effectiveness of the click conjugation cannot be derived. It is demonstrated that under certain conditions multi-modal molecular weight distributions are obtained from two well-defined monomodal initial distributions. Similarly, the comparison of peak maxima between the conjugate and the initial SEC distributions is a poorly defined criterion to assess the success of a conjugation. The only reliable assessment for the success of the click coupling reaction is the true number average molecular weight, M̄π, of the SEC distribution of the click product, as well as a plot of the concentration or number distributions, c versus M, of the precursors and product polymer. © 2009 WILEY-VCH Verlag GmbH & Co. KCaA, Weinheim.

Impact and interest:

23 citations in Scopus
Search Google Scholar™
24 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 99204
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By :23 Export Date: 5 September 2016 CODEN: MRCOE Correspondence Address: Barner-Kowollik, C.; Preparative Macromolecular Chemistry, Institut für Technische Chemie und Polymerchemie, Karlsruhe Institute of Technology (KIT), Engesserstraße 18, 76128 Karlsruhe, Germany; email: christopher.barner-kowollik@polymer.uni-karlsruhe.de References: Kolb, H.C., Finn, M.G., Sharpless, K.B., (2001) Angew. Chem. Int. Ed., 40, p. 2004; Evans, R.A., (2007) Aust. J. Chem., 60, p. 384; Binder, W.H., Sachsenhofer, R., (2008) Macromol. Sapid Commun., 29, p. 952; Binder, W.H., Sachsenhofer, R., (2007) Macromol. Sapid Commun., 28, p. 15; Moses, J.E., Moorhouse, A.D., (2007) Chem. Soc. Rev., 36, p. 1249; Barner-Kowollik, C., Inglis, A.J., (2009) Macromol. Chem. Phys., , DOI: 10.1002/macp.200900139; Nebhani, L., Barner-Kowollik, C., (2009) Adv. Mater., , DOI: 10.1002/adma.200900238; Opsteen, J.A., Van Hest, J.C.M., (2005) Chem. Commun., 57. , See for example: [7a]; Golas, P.L., Tsarevsky, N.V., Sumerlin, B.S., Walker, L.M., Matyjaszewski, K., (2007) Aust. J. Chem., 60, p. 400; Mespouille, L., Vachaudez, M., Suriano, F., Gerbaux, P., Coulembier, O., Degee, P., Flammang, R., Dubois, P., (2007) Macromol. Sapid Commun., 28, p. 2151; Tsarevsky, N.V., Sumerlin, B.S., Matyjaszewski, K., (2005) Macromolecules, 38, p. 3558; Durmaz, H., Colakoclu, B., Tunca, U., Hizal, G., (2006) Polym. Sci, Part A: Polym. Chem., 44, p. 1667; Durmaz, H., Dag, A., Altintas, O., Erdogan, T., Hizal, G., Tunca, U., (2007) Macromolecules, 40, p. 191; He, X.H., Liang, L.Y., Xie, M.R., Zhang, Y.Q., Lin, S.L., Yan, D.Y., (2007) Macromol. Chem. Phys., 208, p. 1797; Golas, P.L., Tsarevsky, N.V., Sumerlin, B.S., Walker, L.M., Matyjaszewski, K., (2007) Aust. J. Chem., 60, p. 400; Lin, W.C., Fu, Q., Zhang, Y., Huang, J.L., (2008) Macromolecules, 41, p. 4127; Quemener, D., Davis, T.P., Barner-Kowollik, C., Stenzel, M.H., (2006) Chem. Commun., 5051; Gao, H., Matyjaszewski, K., (2006) Macromolecules, 39, p. 4960; Inglis, A.J., Sinnwell, S., Davis, T.P., Barnerkowollik, C., Stenzel, M.H., (2008) Macromolecules, 41, p. 4120; Heuts, J.P.A., Forster, D.J., Davis, T.P., (1999) Macromolecules, 32, p. 3907. , See for example; Chiefari, J., Jeffery, J., Mayadunne, R.T.A., Moad, G., Rizzardo, E., Thang, S.H., (1999) Macromolecules, 32, p. 7700; Junkers, T., Bennet, F., Koo, S.P.S., Barner-Kowollik, C., (2008) J. Polym. Sei, Part A: Polym. Chem., 46, p. 3433; Wulkow, M., Busch, M., Davis, T.P., Barner-Kowollik, C., (2004) J. Polym. Sci., Part A: Polym. Chem., 42, p. 1441; Barner-Kowollik, C., Vana, P., Davis, T.P., The Kinetics of Radical Polymerization (2002) Handbook of Sadical Polymerization, , K. Matyjaszewski, T. P. Davis, Eds., Wiley-Interscience, New York; Fukuda, T., (2004) J. Polym. Sci., Part A: Polym. Chem., 42, p. 4743; Guillaneuf, Y., Castignolles, P., (2008) J. Polym. Sci., Part A: Polym. Chem., 46, p. 897; (2009) Handbook of Sing Opening Polymerization, , P. Dubois, O. Coulembier, J-. M. Raquez, Eds., Wiley-VCH, Weinheim, Germany; Inglis, A.J., Sinnwell, S., Stenzel, M.H., Barner-Kowollik, C., (2009) Int. Ed. Angew. Chem., 48, p. 2411; Gaborieau, M., Gilbert, R.G., Gray-Weale, A., Hernandez, J.M., Castignolles, P., (2007) Macromol. Theory Simul., 16, p. 13; Moad, G., Moad, C.L., (1996) Macromolecules, 29, p. 7727. , See for example: [23a]; Bruessau, R.J., (1996) Macromol. Symp., 119, p. 15; Falkenhagen, J., Much, H., Stauf, W., Müller, A.H.E., (2000) Macromolecules, 33, p. 3687. , See for example
Keywords: Click chemistry, Convolution of molecular weight distributions, Polymer conjugation, Coupling reaction, Multi-modal, Number average molecular weight, Number distribution, Peak maxima, Reliable assessment, Block copolymers, Chemical bonds, Chromatographic analysis, Convolution, Molecular weight distribution, Organic polymers, Polymers, Size exclusion chromatography, Weighing
DOI: 10.1002/marc.200900316
ISSN: 10221336
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute for Future Environments
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Deposited On: 22 Sep 2016 04:50
Last Modified: 09 Oct 2016 22:48

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page