Iron predicts tolerance in liver transplantation

Wallace, D.F., Crawford, D.H.G., & Subramaniam, V.N. (2012) Iron predicts tolerance in liver transplantation. Gastroenterology, 143(3), pp. 862-865.

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Abstract

Selected summary of Bohne F, Martínez-Llordella M, Lozano JJ, et al. Intragraft expression of genes involved in iron homeostasis predicts the development of operational tolerance in human liver transplantation. J Clin Invest 2012;122: 368–382.

Lifetime immunosuppressive therapy, which is usually needed to prevent rejection of the graft in solid organ transplantation, may have serious side effects resulting in increased morbidity and mortality. The liver is unique in organ transplantation; up to 20% of transplant recipients can be weaned off immunosuppressive drugs and display “operational tolerance” of the graft in the absence of immunosuppression (Transplantation 2011;91:1065–1974)...

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ID Code: 99841
Item Type: Journal Article
Refereed: Yes
DOI: 10.1053/j.gastro.2012.07.091
ISSN: 1528-0012
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Deposited On: 14 Oct 2016 01:25
Last Modified: 17 Oct 2016 04:16

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