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Characterization of autonomic dysfunction in patients with irritable bowel syndrome by means of heart rate variability studies

Adeyemi, Edward O. A. and Desai, K.D. and Towsey, Michael W. and Ghista, Dhanjoo N. (1999) Characterization of autonomic dysfunction in patients with irritable bowel syndrome by means of heart rate variability studies. American Journal of Gastroenterology 94(3):pp. 816-823.

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Abstract

Objective: To characterize autonomic dysfunction in patients with irritable bowel syndrome (IBS) using heart rate variability (HRV) studies. Methods: EKG signals were obtained from 35 patients and 18 healthy controls in supine, standing and deep breathing modes. HRV power spectra were analysed. Results: In the supine position, the very low frequency (VLF) power spectral density (PSD) in IBS patients was significantly higher than in normals. On changing from supine to standing position, the normal controls had raised median PSD. Conclusion: IBS patients have reduced sympathetic influence on the heart period in response to orthostatic stress and diminished parasympathetic modulation during deep breathing.

Item Type:Journal Article
Status:Published
Subjects:280000 Information, Computing and Communication Sciences > 280200 Artificial Intelligence and Signal and Image Processing > 280204 Signal Processing
320000 Medical and Health Sciences > 321000 Clinical Sciences > 321006 Gastroenterology and Hepatology
ID Code:7603
Deposited By:Towsey, Michael W.
Deposited On:15 May 2007
Alternative Locations:http://dx.doi.org/10.1111/j.1572-0241.1999.00861.x
Copyright Owner:Copyright 1999 Blackwell Publishing
Copyright Statement:The definitive version is available at www.blackwell-synergy.com
Additional Information:Abstract only. For more information please contact the author: m.towsey@qut.edu.au