Use of a matrix scaffold for tissue engineering and bone regeneration
(2003) Use of a matrix scaffold for tissue engineering and bone regeneration, in Ellingsen, Jan Eirik and Lyngstadaas, S. Petter, Eds. Bio-implant interface : improving biomaterials and tissue reactions, chapter 14, pages pp. 243-254. CRC Press.
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Abstract
The regeneration of bone defects resulting from tumors, diseases, infections, trauma, biochemical disorders, and abnormal skeletal development posese a significant clinical challenge. Over the years, many bone graft substitites including autografts, allograft, and synthetic materials have been developed. In this chapter, we demonstrated how cells from avelolar bone retain their osteogenic properties in a three-dimensional collagen scvaffold and subsequently synthesize a bone matrix which, after implantation, can induce new bone formation in critical size calvarial defects.
| Item Type: | Book Chapter |
|---|---|
| Status: | Published |
| Place of Publication: | Boca Raton, Fla. |
| Subjects: | 270000 Biological Sciences > 270100 Biochemistry and Cell Biology > 270105 Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) |
| ID Code: | 9181 |
| Deposited By: | Xiao, Yin |
| Deposited On: | 27 August 2007 |
| Alternative Locations: | http://www.crcpress.com/ |
| Copyright Owner: | Copyright 2003 CRC Press |
| Additional Information: | For more information about this book please refer to the publisher's website (see link) or contact the author. Author contact details : yin.xiao@qut.edu.au |