Browse By Person: Bolderson, Emma
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Number of items: 24.
Bolderson, Emma, Scorah, Jennifer, Helleday, Thomas, Smythe, Carl, & Meuth, Mark (2004) ATM is required for the cellular response to thymidine induced replication fork stress. Human Molecular Genetics, 13(23), pp. 2937-2945.
Mohindra, Atul, Bolderson, Emma, Stone, Jason, Wells, Michael, Helleday, Thomas, & Meuth, Mark (2004) A tumour-derived mutant allele of XRCC2 preferentially suppresses homologous recombination at DNA replication forks. Human Molecular Genetics, 13(2), pp. 203-212.
Catto, James W.F., Hartmann, Arndt, Stoehr, Robert, Bolderson, Emma, Rehman, Ishtiaq, Rosario, Derek J., et al. (2006) Multifocal urothelial cancers with the mutator phenotype are of monoclonal origin and require panurothelial treatment for tumor clearance. The Journal of Urology, 175(6), pp. 2323-2330.
Richard, Derek J., Bolderson, Emma, Cubeddu, Liza, Wadsworth, Ross I. M., Savage, Kienan, Sharma, Girdhar G., et al. (2008) Single-stranded DNA-binding protein hSSB1 is critical for genomic stability. Nature, 453(7195), pp. 677-681.
Pagan, Julia K., Bolderson, Emma, Jones, Mathew J. K., & Khanna, Kum Kum (2009) Chromatin modifications involved in the DNA damage response to double strand breaks. In Khanna, Kum Kum & Shiloh, Yosef (Eds.) The DNA Damage Response: Implications on Cancer Formation and Treatment. Springer, pp. 109-131.
Skaar, Jeffrey R., Richard, Derek J., Saraf, Anita, Toschi, Alfredo, Bolderson, Emma, Florens, Laurence, et al. (2009) INTS3 controls the hSSB1-mediated DNA damage response. The Journal of Cell Biology, 187(1), pp. 25-32.
Bolderson, Emma, Richard, Derek J., Edelmann, Winfried, & Khanna, Kum Kum (2009) Involvement of Exo1b in DNA damage-induced apoptosis. Nucleic Acids Research, 37(10), pp. 3452-3463.
Richard, Derek, Bolderson, Emma, & Khanna, Kum Kum (2009) Multiple human single-stranded DNA binding proteins function in genome maintenance : structural, biochemical and functional analysis. Critical Reviews in Biochemistry and Molecular Biology, 44(2-3), pp. 98-116.
Bolderson, Emma, Richard, Derek J., Zhou, Bin-Bing S., & Khanna, Kum Kum (2009) Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair. Clinical Cancer Research, 15(20), pp. 6314-6320.
Bolderson, Emma, Tomimatsu, Nozomi, Richard, Derek J., Boucher, Didier, Kumar, Rakesh, Pandita, Tej K., et al. (2010) Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks. Nucleic Acids Research, 38(6), pp. 1821-1831.
Papp, Laura V., Lu, Jun, Bolderson, Emma, Boucher, Didier, Singh, Ravindra, Holmgren, Arne, et al. (2010) SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress. Antioxidants & Redox Signaling, 12(7), pp. 797-808.
Richard, Derek J., Cubeddu, Liza, Urquhart, Aaron J., Bain, Amanda, Bolderson, Emma, Menon, Dinoop, et al. (2011) hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity. Nucleic Acids Research, 39(9), pp. 3643-3651.
Richard, Derek J., Savage, Kienan, Bolderson, Emma, Cubeddu, Liza, So, Sairei , Ghita, Mihaela, et al. (2011) hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex. Nucleic Acids Research, 39(5), pp. 1692-1702.
Bolderson, Emma, Savage, K. I., Mahen, R., Pisupati, V., Graham, M. E., Richard, Derek J., et al. (2012) Krüppel-associated box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1 (HP1- ) mobilization and DNA repair in heterochromatin. Journal of Biological Chemistry, 287(33), pp. 28122-28131.
Tomimatsu, Nozomi, Mukherjee, Bipasha, Deland, Katherine, Kurimasa, Akihiro, Bolderson, Emma, Khanna, Kum Kum, et al. (2012) Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions. DNA Repair, 11(4), pp. 441-448.
Adams, Mark N., Leong, Vincent, Paquet, Nicolas, Bolderson, Emma, Fennell, Dean A., O'Byrne, Kenneth, et al. (2013) HSSB1: An essential regulator of genomic integrity in lung cancer. In 15th World Conference on Lung Cancer, 27-30 October 2013, Sydney, NSW.
Ashton, Nicholas W., Bolderson, Emma, Cubeddu, Liza, O’Byrne, Kenneth J., & Richard, Derek J. (2013) Human single-stranded DNA binding proteins are essential for maintaining genomic stability. BMC Molecular Biology, 14, Article no. 9.
Paquet, Nicolas, Box, Joseph K, Ashton, Nicholas W., Suraweera, Amila, Croft, Laura V, Urquhart, Aaron J., et al. (2014) Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation. BMC Molecular Biology, 15(1), pp. 1-11.
Jekimovs, Christian, Bolderson, Emma, Suraweera, Amila, Adams, Mark, O'Byrne, Kenneth J., & Richard, Derek J. (2014) Chemotherapeutic compounds targeting the DNA double-strand break repair pathways : the good, the bad, and the promising. Frontiers in Oncology, 4(86).
Bolderson, Emma, Petermann, Eva, Croft, Laura, Suraweera, Amila, Pandita, Raj K., Pandita, Tej K., et al. (2014) Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks. Nucleic Acids Research, 42(10), pp. 6326-6336.
Wiegmans, Adrian P., Al-Ejeh, Fares, Chee, Nicole, Yap, Pei-Yi, Gorski, Julia J., Da Silva, Leonard, et al. (2014) Rad51 supports triple negative breast cancer metastasis. Oncotarget, 5(10), pp. 3261-3272.
Paquet, Nicolas, Adams, Mark N., Leong, Vincent, Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, et al. (2015) hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway. Nucleic Acids Research, 43(18), pp. 8817-8829.
Paquet, Nicolas, Adams, Mark N., Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, Cubeddu, Liza, et al. (2016) hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress. Scientific Reports, 6, Article number: 27446.
O'Byrne, K.J., Burgess, J., Bolderson, E., Adams, M., Zhang, S-D, & Richard, D. (2016) The overexpression of SASH1 stimulates cell death in lung cancer cells. In European Lung Cancer Conference (ELCC 2016), 13 - 16 April 2016, Geneva, Switzerland.