Browse By Person: Richard, Derek

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Number of items: 66.

Book Chapter

Baird, Anne-Marie, Richard, Derek J., O’Byrne, Kenneth J., & Gray, Steven G. (2015) Epigenetic therapy in lung cancer and mesothelioma. In Gray, Steven G. (Ed.) Epigenetic Cancer Therapy. Academic Press (Elsevier), Amsterdam, pp. 189-213.
Number of citations in Scopus 1

Adams, Mark N., Ashton, Nicholas W., Paquet, Nicolas, O'Byrne, Kenneth J., & Richard, Derek J. (2014) Mechanisms of cisplatin resistance: DNA repair and cellular implications. In Morais, Christudas (Ed.) Advances in Drug Resistance Research. Nova Science Publishers, New York, pp. 1-37.

Richard, Derek & Khanna, Kum (2009) Single-stranded DNA binding proteins involved in genome maintenance. In Khanna, K & Shiloh, Y (Eds.) The DNA Damage Response: Implications on Cancer Formation and Treatment. Springer, Germany, pp. 349-366.
Number of citations in Scopus 1
Number of citations in Web of Science® 4

Journal Article

Box, Joseph K., Paquet, Nicolas, Adams, Mark N., Boucher, Didier, Bolderson, Emma, O’Byrne, Kenneth J., et al. (2016) Nucleophosmin: From structure and function to disease development. BMC Molecular Biology, 17, Article no. 19.
Number of full-text downloads 1

Touma, Christine, Kariawasam, Ruvini, Gimenez, Adrian X., Bernardo, Ray E., Ashton, Nicholas W., Adams, Mark N., et al. (2016) A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution. Nucleic Acids Research. (In Press)
Number of full-text downloads 1

Paquet, Nicolas, Adams, Mark N., Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, Cubeddu, Liza, et al. (2016) hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress. Scientific Reports, 6, Article number: 27446.

Ryan, Sarah-Louise, Baird, Anne-Marie, Vaz, Gisela, Urquhart, Aaron J., Senge, Mathias, Richard, Derek J., et al. (2016) Drug discovery approaches utilizing three-dimensional cell culture. ASSAY and Drug Development Technologies, 14(1), pp. 19-28.
Number of citations in Web of Science® 1

Baird, Anne-Marie, Gray, Steven G., Richard, Derek J., & O’Byrne, Kenneth J. (2016) Promotion of a cancer-like phenotype, through chronic exposure to inflammatory cytokines and hypoxia in a bronchial epithelial cell line model. Scientific Reports, 6, Article no. 18907.
Number of full-text downloads 5
Number of citations in Scopus 1
Number of citations in Web of Science® 1

Yeo, Abrey J, Becherel, Olivier J, Luff, John E, Graham, Mark E, Richard, Derek, & Lavin, Martin F (2015) Senataxin controls meiotic silencing through ATR activation and chromatin remodeling. Cell Discovery, 1(15025), pp. 1-20.

Barr, Martin P., Gray, Steven G., Gately, Kathy, Hams, Emily, Fallon, Padraic G., Davies, Anthony Mitchell, et al. (2015) Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer. Molecular Cancer, 14(45).
Number of full-text downloads 7
Number of citations in Scopus 9
Number of citations in Web of Science® 8

Gamsjaeger, Roland, Kariawasam, Ruvini, Gimenez, Adrian X., Touma, Christine, McIlwain, Elysse, Bernardo, Ray E., et al. (2015) The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus. Biochemical Journal, 465(2), pp. 337-346.
Number of citations in Scopus 3
Number of citations in Web of Science® 2

Paquet, Nicolas, Adams, Mark N., Leong, Vincent, Ashton, Nicholas W., Touma, Christine, Gamsjaeger, Roland, et al. (2015) hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway. Nucleic Acids Research, 43(18), pp. 8817-8829.
Number of full-text downloads 19
Number of citations in Web of Science® 1

Paquet, Nicolas, Box, Joseph K, Ashton, Nicholas W., Suraweera, Amila, Croft, Laura V, Urquhart, Aaron J., et al. (2014) Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation. BMC Molecular Biology, 15(1), pp. 1-11.
Number of citations in Scopus 3
Number of citations in Web of Science® 1

O’Grady, Shane, Finn, Stephen P., Cuffe, Sinead, Richard, Derek J., O’Byrne, Kenneth J., & Barr, Martin P. (2014) The role of DNA repair pathways in cisplatin resistant lung cancer. Cancer Treatment Reviews, 40(10), pp. 1161-1170.
Number of citations in Scopus 17
Number of citations in Web of Science® 13

Shandilya, Jayasha, Toska, Eneda, & Richard, Derek J. (2014) WT1 interacts with MAD2 and regulates mitotic checkpoint function. Nature Communications, 5(4903), pp. 1-9.
Number of full-text downloads 14
Number of citations in Scopus 2
Number of citations in Web of Science® 1

Tickner, Jacob A, Urquhart, Aaron J., Stephenson, Sally-Anne, Richard, Derek J., & O'Byrne, Kenneth J. (2014) Functions and therapeutic roles of exosomes in cancer. Frontiers in Oncology, 4, pp. 127-1.
Number of citations in Scopus 40

Jekimovs, Christian, Bolderson, Emma, Suraweera, Amila, Adams, Mark, O'Byrne, Kenneth J., & Richard, Derek J. (2014) Chemotherapeutic compounds targeting the DNA double-strand break repair pathways : the good, the bad, and the promising. Frontiers in Oncology, 4(86).
Number of full-text downloads 85
Number of citations in Scopus 15

Savage, Kienan I., Matchett, Kyle B., Barros, Eliana M., Cooper, Kevin M., Irwin, Gareth W., Gorski, Julia J., et al. (2014) BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability. Cancer Research, 74(10), pp. 2773-2784.
Number of full-text downloads 11
Number of citations in Scopus 24
Number of citations in Web of Science® 17

Bolderson, Emma, Petermann, Eva, Croft, Laura, Suraweera, Amila, Pandita, Raj K., Pandita, Tej K., et al. (2014) Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks. Nucleic Acids Research, 42(10), pp. 6326-6336.
Number of full-text downloads 42
Number of citations in Scopus 10
Number of citations in Web of Science® 8

Savage, Kienan I., Gorski, Julia J., Barros, Eliana M., Irwin, Gareth W., Manti, Lorenzo, Powell, Alexander J., et al. (2014) Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability. Molecular Cell, 54(3), pp. 445-459.
Number of full-text downloads 7
Number of citations in Scopus 29
Number of citations in Web of Science® 27

Barr, Martin P., Gray, Steven G., Hoffmann, Andreas C., Hilger, Ralf A., Thomale, Juergen, O' Flaherty, John D, et al. (2013) Generation and characterisation of Cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature. PLoS ONE, 8(1), e54193.
Number of full-text downloads 15
Number of citations in Scopus 59
Number of citations in Web of Science® 46

Gray, S.G., Barr, M.P., Fennell, D.A., O'Leary, J.J., Richard, Derek J., Thomale, J., et al. (2013) 2 MicroRNA profiling and cisplatin--DNA interactions in an isogenic model of cisplatin resistant NSCLC cell lines. Lung Cancer, 79(Supp1), S1.

Kavanagh, J.N., Currell, F.J., Timson, D.J., Savage, K.I., Richard, D.J., McMahon, S.J., et al. (2013) Antiproton induced DNA damage : proton like in flight, carbon-ion light near rest. Scientific Reports, 3(1770).
Number of citations in Scopus 7
Number of citations in Web of Science® 5

Jenkins, Glenn, O'Byrne, Kenneth J., Panizza, Benedict, & Richard, Derek J. (2013) Genome stability pathways in head and neck cancers. International Journal of Genomics, 2013(464720).
Number of full-text downloads 56
Number of citations in Scopus 7
Number of citations in Web of Science® 6

Ashton, Nicholas W., Bolderson, Emma, Cubeddu, Liza, O’Byrne, Kenneth J., & Richard, Derek J. (2013) Human single-stranded DNA binding proteins are essential for maintaining genomic stability. BMC Molecular Biology, 14, Article no. 9.
Number of full-text downloads 14
Number of citations in Scopus 13
Number of citations in Web of Science® 12

O’Flaherty, John D., Barr, Martin, Fennell, Dean, Richard, Derek, Reynolds, John, O’Leary, John, et al. (2012) The cancer stem-cell hypothesis : its emerging role in lung cancer biology and its relevance for future therapy. Journal of Thoracic Oncology, 7(12), pp. 1880-1890.
Number of citations in Scopus 41
Number of citations in Web of Science® 39

Bolderson, Emma, Savage, K. I., Mahen, R., Pisupati, V., Graham, M. E., Richard, Derek J., et al. (2012) Krüppel-associated box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1 (HP1- ) mobilization and DNA repair in heterochromatin. Journal of Biological Chemistry, 287(33), pp. 28122-28131.
Number of citations in Scopus 23
Number of citations in Web of Science® 18

Cubeddu, Liza, Joseph, Soumya, Richard, Derek J., & Matthews, Jacqueline M. (2012) Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4. PLoS ONE, 7(6), e39218.
Number of full-text downloads 86
Number of citations in Scopus 10
Number of citations in Web of Science® 10

Busacca, Sara, Sheaff, Michael, Arthur, Kenneth, Gray, Steven G, O'Byrne, Kenneth J., Richard, Derek J., et al. (2012) BRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma. The Journal of Pathology, 227(2), pp. 200-208.
Number of citations in Scopus 11
Number of citations in Web of Science® 11

Morris, Christelle, Tomimatsu, Nozomi , Richard, Derek J., Cluet, David, Burma, Sandeep, Khanna, Kum Kum , et al. (2012) INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells. Cancer Research, 72(8), pp. 2006-2016.
Number of citations in Scopus 4
Number of citations in Web of Science® 2

O’Flaherty, John D., Gray, Steven, Richard, Derek, Fennell, Dean, O’Leary, John J., Blackhall, Fiona H., et al. (2012) Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer. Lung Cancer, 76(1), pp. 19-25.
Number of citations in Scopus 58
Number of citations in Web of Science® 49

Paul, Ian, Savage, Kienan I, Blayney, Jaine K, Lamers, Elisabeth, Gately, Kathy, Kerr, Keith, et al. (2011) PARP inhibition induces BAX/BAK-independent synthetic lethality of BRCA1-deficient non-small cell lung cancer. Journal of Pathology, 224(4), pp. 564-574.
Number of citations in Scopus 19
Number of citations in Web of Science® 19

Wykes, Michele, Richard, Derek J., Kay, Jason G., Manderson, Anthony, Liu, Xue Q., Brown, Darren L., et al. (2011) Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice. Proceedings of the National Academy of Sciences, 108(27), pp. 11205-11210.
Number of citations in Scopus 31
Number of citations in Web of Science® 31

Urquhart, Aaron J., Gatei, Magtouf, Richard, Derek J., & Khanna, Kum Kum (2011) ATM mediated phosphorylation of CHD4 contributes to genome maintenance. Genome Integrity, 2(1), pp. 1-12.
Number of full-text downloads 86
Number of citations in Scopus 15

Schettino, G., Ghita, M., Richard, D. J., & Prise, K. M. (2011) Spatiotemporal investigations of DNA damage repair using microbeams. Radiation Protection Dosimetry, 143(2-4), p. 340.
Number of citations in Scopus 3
Number of citations in Web of Science® 3

Richard, Derek J., Cubeddu, Liza, Urquhart, Aaron J., Bain, Amanda, Bolderson, Emma, Menon, Dinoop, et al. (2011) hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity. Nucleic Acids Research, 39(9), pp. 3643-3651.
Number of full-text downloads 24
Number of citations in Scopus 30
Number of citations in Web of Science® 29

Richard, Derek J., Savage, Kienan, Bolderson, Emma, Cubeddu, Liza, So, Sairei , Ghita, Mihaela, et al. (2011) hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex. Nucleic Acids Research, 39(5), pp. 1692-1702.
Number of full-text downloads 29
Number of citations in Scopus 31
Number of citations in Web of Science® 27

Bolderson, Emma, Tomimatsu, Nozomi, Richard, Derek J., Boucher, Didier, Kumar, Rakesh, Pandita, Tej K., et al. (2010) Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks. Nucleic Acids Research, 38(6), pp. 1821-1831.
Number of full-text downloads 71
Number of citations in Scopus 66
Number of citations in Web of Science® 60

Skaar, Jeffrey R., Richard, Derek J., Saraf, Anita, Toschi, Alfredo, Bolderson, Emma, Florens, Laurence, et al. (2009) INTS3 controls the hSSB1-mediated DNA damage response. The Journal of Cell Biology, 187(1), pp. 25-32.
Number of full-text downloads 53
Number of citations in Scopus 39
Number of citations in Web of Science® 38

Bolderson, Emma, Richard, Derek J., Edelmann, Winfried, & Khanna, Kum Kum (2009) Involvement of Exo1b in DNA damage-induced apoptosis. Nucleic Acids Research, 37(10), pp. 3452-3463.
Number of full-text downloads 60
Number of citations in Scopus 18
Number of citations in Web of Science® 17

Richard, Derek, Bolderson, Emma, & Khanna, Kum Kum (2009) Multiple human single-stranded DNA binding proteins function in genome maintenance : structural, biochemical and functional analysis. Critical Reviews in Biochemistry and Molecular Biology, 44(2-3), pp. 98-116.
Number of citations in Scopus 39
Number of citations in Web of Science® 42

Bolderson, Emma, Richard, Derek J., Zhou, Bin-Bing S., & Khanna, Kum Kum (2009) Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair. Clinical Cancer Research, 15(20), pp. 6314-6320.
Number of citations in Scopus 119
Number of citations in Web of Science® 113

Li, Yongjian, Bolderson, Emma, Kumar, Rakesh, Muniandy, Parameswary, Xue, Yutong, Richard, Derek, et al. (2009) hSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response. Journal of Biological Chemistry, 284(35), pp. 23525-23531.
Number of citations in Scopus 51
Number of citations in Web of Science® 48

Richard, Derek J., Bolderson, Emma, Cubeddu, Liza, Wadsworth, Ross I. M., Savage, Kienan, Sharma, Girdhar G., et al. (2008) Single-stranded DNA-binding protein hSSB1 is critical for genomic stability. Nature, 453(7195), pp. 677-681.
Number of citations in Scopus 118
Number of citations in Web of Science® 113

Pagan, Julia K., Arnold, Jeremy, Hanchard, Kim J., Kumar, Raman, Bruno, Tiziana, Jones, Mathew J. K., et al. (2007) A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. Journal of Biological Chemistry, 282(20), pp. 15248-15257.
Number of citations in Scopus 23
Number of citations in Web of Science® 23

Ariza, Antonio, Richard, Derek J., White, Malcolm F., & Bond, Charles S. (2005) Conformational flexibility revealed by the crystal structure of a crenarchaeal RadA. Nucleic Acids Research, 33(5), p. 1465.
Number of full-text downloads 43
Number of citations in Scopus 24
Number of citations in Web of Science® 23

Jekimovs, C.R., Chen, X., Arnold, J., Gatei, M., Richard, D.J., Spurdle, A.B., et al. (2005) Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families : functional analysis in heterozygous individuals. British Journal of Cancer, 92(4), pp. 784-790.
Number of citations in Scopus 25
Number of citations in Web of Science® 26

Richard, D.J. (2004) Physical and functional interaction of the archaeal single-stranded DNA-binding protein SSB with RNA polymerase. Nucleic Acids Research, 32(3), pp. 1065-1074.
Number of full-text downloads 57
Number of citations in Scopus 39
Number of citations in Web of Science® 38

Middleton, Claire L., Parker, Joanne L., Richard, Derek J., White, Malcolm F., & Bond, Charles S. (2004) Substrate recognition and catalysis by the Holliday junction resolving enzyme Hje. Nucleic Acids Research, 32(18), pp. 5442-5451.
Number of full-text downloads 65
Number of citations in Scopus 30
Number of citations in Web of Science® 28

Richard, Derek J., Schumacher, Vale´ rie , Royer-Pokora, Brigitte, & Roberts, Stefan G.E. (2001) Par4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1. Genes and Development, 15(3), pp. 328-339.
Number of citations in Scopus 64
Number of citations in Web of Science® 61

Conference Item

O'Byrne, K., Ryan, S.-L., Baird, A.-M., Urquhart, A., Richard, D., & Davies, A. (2016) Elucidating drug resistance mechanisms using 2D and 3D culture systems. In ELCC 2016 European Lung Cancer Conference, 13–16 April 2016, Geneva, Switzerland.

O'Byrne, K., Adams, M., Burgess, J., & Richard, D. (2016) CDCA3 regulates the cell cycle and modulates cisplatin sensitivity in non-small cell lung cancer. In European Lung Cancer Conference (ELCC 2016), 13 - 16 April 2016, Geneva, Switzerland.

O'Byrne, K., Paquet, N., Box, J.K., Adams, M., & Richard, D. (2016) Examination of EXOSC4 as a new prognostic marker and a novel therapeutic avenue in lung adenocarcinoma. In European Lung Cancer Conference (ELCC 2016), 13 - 16 April 2016, Geneva, Switzerland.

O'Byrne, K., Ryan, S-L, Heavey, S., Umezawa, K., Barr, M.P., Gray, S.G., et al. (2016) Inflammatory meditated mechanisms of cisplatin resistance in non-small cell lung cancer. In European Lung Cancer Conference (ELCC 2016), 13 - 16 April 2016, Geneva, Switzerland.

O'Byrne, K., Barr, M.P., Urquhart, A., Ryan, S.-L., Gray, S.G., Davies, A., et al. (2016) Investigation of the interaction between non-small cell lung cancer cells and immortalised normal bronchial epithelial cells. In European Lung Cancer Conference (ELCC 2016), 13 - 16 April 2016, Geneva, Switzerland.

O'Byrne, K.J., Burgess, J., Bolderson, E., Adams, M., Zhang, S-D, & Richard, D. (2016) The overexpression of SASH1 stimulates cell death in lung cancer cells. In European Lung Cancer Conference (ELCC 2016), 13 - 16 April 2016, Geneva, Switzerland.

Barr, M.P., Buckley, P.G., Alcock, L.C., Stallings, R.L., Toomey, S., Carr, A., et al. (2014) Chromosomal and mutational analysis of the cisplatin resistant phenotype in NSCLC. In 12th Annual British Thoracic Oncology Group Conference, 29-31 January 2014, Dublin, Ireland.

Barr, M.P., Rausch, R., Thomale, J., Richard, D., Cuffe, S., Finn, S., et al. (2014) Inhibition of PARP activity by PJ34 sensitises NSCLC cells to cisplatin. In 12th Annual British Thoracic Oncology Group Conference, 29-31 January 2014, Dublin, Ireland.

Baird, A.-M., Godwin, P., Heavey, S., Umezawa, K., Barr, M.P., Richard, D., et al. (2014) Targeting NF-κB regulated pathways to overcome cisplatin resistance in non-small cell lung cancer. In 12th Annual British Thoracic Oncology Group Conference, 29-31 January 2014, Dublin, Ireland.

Barr, M.P., Gray, G., Gately, K.A., Hams, E., Fallon, P.G., Davies, A. Mitchell, et al. (2014) VEGF autocrine survival signalling is mediated via neuropilin 1 receptor in NSCLC cells. In 12th Annual British Thoracic Oncology Group Conference, 29-31 January 2014, Dublin, Ireland.

Barr, Martin P., Alcock, Leah C., Stallings, Raymond L., Toomey, Sinead, Carr, Aoife, Hennessy, Bryan T., et al. (2013) Chromosomal and mutational analysis of the cisplatin resistant phenotype in NSCLC cells. In 15th World Conference on Lung Cancer, 27-30 October 2013, Sydney, NSW.

Adams, Mark N., Leong, Vincent, Paquet, Nicolas, Bolderson, Emma, Fennell, Dean A., O'Byrne, Kenneth, et al. (2013) HSSB1: An essential regulator of genomic integrity in lung cancer. In 15th World Conference on Lung Cancer, 27-30 October 2013, Sydney, NSW.

Rausch, Raya, Barr, Martin P., Thomale, Juergen, Richard, Derek, & O'Byrne, Kenneth (2013) PARP inhibition increases sensitivity of NSCLC cells to cisplatin. In 15th World Conference on Lung Cancer, 27-30 October 2013, Sydney, NSW.

Baird, Anne-Marie, Godwin, Peter, Heavey, Susan, Umezawa, Kazuo, Barr, Martin, Richard, Derek, et al. (2013) Targeting NF-κB regulated pathways to overcome cisplatin resistance in non small cell lung cancer. In 15th World Conference on Lung Cancer, 27-30 October 2013, Sydney, NSW.

Review

Pham, Thy, Sadowski, Martin C., Li, Huika, Richard, Derek J., d’Emden, Michael C., & Richard, Kerry (2016) Advances in hormonal therapies for hormone naïve and castration-resistant prostate cancers with or without previous chemotherapy. Experimental Hematology & Oncology, 5, Article Number -15.
Number of full-text downloads 2

Burgess, Joshua T., Croft, Laura V., Wallace, Nathan C., Stephenson, Sally-Anne, Adams, Mark N., Ashton, Nicholas W., et al. (2014) DNA repair pathways and their therapeutic potential in lung cancer. Lung Cancer Management, 3(2), pp. 159-173.

This list was generated on Sat Sep 24 15:07:03 2016 AEST.