Browse By Person: Brown, Matt

Major, Tanya J., Takei, Riku, Matsuo, Hirotaka, Leask, Megan P., Sumpter, Nicholas A., Topless, Ruth K., Shirai, Yuya, Wang, Wei, Cadzow, Murray J., Phipps-Green, Amanda J., Li, Zhiqiang, Ji, Aichang, Merriman, Marilyn E., Morice, Emily, Kelley, Eric E., Wei, Wen Hua, McCormick, Sally P.A., Bixley, Matthew J., Reynolds, Richard J., Saag, Kenneth G., Fadason, Tayaza, Golovina, Evgenia, O’Sullivan, Justin M., Stamp, Lisa K., Dalbeth, Nicola, Abhishek, Abhishek, Doherty, Michael, Roddy, Edward, Jacobsson, Lennart T.H., Kapetanovic, Meliha C., Melander, Olle, Andrés, Mariano, Pérez-Ruiz, Fernando, Torres, Rosa J., Radstake, Timothy, Jansen, Timothy L., Janssen, Matthijs, Joosten, Leo A.B., Liu, Ruiqi, Gaal, Orsolya I., Crişan, Tania O., Rednic, Simona, Kurreeman, Fina, Huizinga, Tom W.J., Toes, René, Lioté, Frédéric, Richette, Pascal, Bardin, Thomas, Ea, Hang Korng, Pascart, Tristan, McCarthy, Geraldine M., Helbert, Laura, Stibůrková, Blanka, Tausche, Anne K., Uhlig, Till, Vitart, Véronique, Boutin, Thibaud S., Hayward, Caroline, Riches, Philip L., Ralston, Stuart H., Campbell, Archie, MacDonald, Thomas M., Nakayama, Akiyoshi, Takada, Tappei, Nakatochi, Masahiro, Shimizu, Seiko, Kawamura, Yusuke, Toyoda, Yu, Nakaoka, Hirofumi, Yamamoto, Ken, Matsuo, Keitaro, Shinomiya, Nariyoshi, Ichida, Kimiyoshi, Lee, Chaeyoung, Bradbury, Linda A., Brown, Matthew A., Robinson, Philip C., Buchanan, Russell R.C., Hill, Catherine L., Lester, Susan, Smith, Malcolm D., Rischmueller, Maureen, Choi, Hyon K., Stahl, Eli A., Miner, Jeff N., Solomon, Daniel H., Cui, Jing, Giacomini, Kathleen M., Brackman, Deanna J., Jorgenson, Eric M., Liu, Hongbo, Susztak, Katalin, Shringapure, Suyash, Shringarpure, Suyash, So, Alexander, Okada, Yukinori, Li, Changgui, Shi, Yongyong, Merriman, Tony R., & other, and (2024) A genome-wide association analysis reveals new pathogenic pathways in gout. Nature Genetics, 56(11), pp. 2392-2406.

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Li, Zhixiu, Khan, Mohammad Kazim, Van Der Linden, Sjef M., Winkens, Bjorn, Villiger, Peter M., Baumberger, Heinz, Van Zandwijk, Hermine, Khan, Muhammad Asim, & Brown, Matthew A. (2023) HLA-B27, axial spondyloarthritis and survival. Annals of the Rheumatic Diseases, 82(12), pp. 1558-1567.

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Mauro, Daniele, Srinath, Archita, Guggino, Giuliana, Nicolaidou, Vicky, Raimondo, Stefania, Ellis, Jonathan J., Whyte, Jessica, Nicoletti, Maria Maddalena, Romano, Marco, Kenna, Tony John, Cañete, Juan D., Alessandro, Riccardo, Rizzo, Aroldo, Brown, Matthew Arthur, Horwood, Nicole J., Haroon, Nigil, & Ciccia, Francesco (2023) Prostaglandin E2/EP4 axis is upregulated in Spondyloarthritis and contributes to radiographic progression. Clinical Immunology, 251, Article number: 109332.

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Hassan, Neelam, Gregson, Celia L., Tang, Haotian, van der Kamp, Marc, Leo, Paul, McInerney-Leo, Aideen M., Zheng, Jie, Brandi, Maria Luisa, Tang, Jonathan C.Y., Fraser, William, Stone, Michael D., Grundberg, Elin, Brown, Matthew A., Duncan, Emma L., Tobias, Jonathan H., & other, and (2023) Rare and Common Variants in GALNT3 May Affect Bone Mass Independently of Phosphate Metabolism. Journal of Bone and Mineral Research, 38(5), pp. 678-691.

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Stoll, M. L., Sawhney, H., Wells, Philippa M., Sternes, P. R., Reveille, J. D., Morrow, C. D., Steves, C. J., Brown, M. A., & Gensler, L. S. (2023) The faecal microbiota is distinct in HLA-B27 + ankylosing spondylitis patients versus HLA-B27 + healthy controls. Clinical and Experimental Rheumatology, 41(5), pp. 1096-1104.

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Bhuyan, Zaied Ahmed, Rahman, M. Arifur, Maradana, Muralidhara Rao, Mehdi, Ahmed M., Bergot, Anne Sophie, Simone, Davide, El-Kurdi, Marya, Garrido-Mesa, Jose, Cai, Cheng Bang Benjamin, Cameron, Amy J., Hanson, Aimee L., Nel, Hendrik J., Kenna, Tony, Leo, Paul, Rehaume, Linda, Brown, Matthew A., Ciccia, Francesco, & Thomas, Ranjeny (2023) Genetically encoded Runx3 and CD4+ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy. Clinical Immunology, 247, Article number: 109220.

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Li, Zhixiu, McRae, Allan F., Wang, Geng, Ellis, Jonathan J., Whyte, Jessica, Kenna, Tony J., Brown, Matthew A., & Evans, David M. (2023) Genotype by sex interactions in ankylosing spondylitis. Nature Genetics, 55(1), pp. 14-16.

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Sternes, P. R., Brett, L., Phipps, J., Ciccia, F., Kenna, T., de Guzman, E., Zimmermann, K., Morrison, M., Holtmann, G., Klingberg, E., Mauro, D., McIvor, C., Forsblad-d’Elia, H., & Brown, M. A. (2022) Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity. Arthritis Research and Therapy, 24, Article number: 163.

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Li, Zhixiu, Khan, Mohammad K., Villiger, Peter M., van der Linden, Sjef, Brown, Matthew A., & Khan, Muhammad A. (2022) Mortality in ankylosing spondylitis according to treatment: comment on the article by Ben Shabat et al. Arthritis Care and Research, 74(12), pp. 2120-2121.

Van Der Linden, Sjef M., Khan, Muhammad Asim, Li, Zhixiu, Baumberger, Heinz, Zandwijk, Hermine Van, Khan, Mohammad Kazim, Villiger, Peter M., & Brown, Matthew A. (2022) Recurrence of axial spondyloarthritis among first-degree relatives in a prospective 35-year-follow-up family study. RMD Open, 8(2), Article number: e002208.

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Hanson, Aimee L., Sahhar, Joanne, Ngian, Gene Siew, Roddy, Janet, Walker, Jennifer, Stevens, Wendy, Nikpour, Mandana, Assassi, Shervin, Proudman, Susanna, Mayes, Maureen D., Kenna, Tony J., & Brown, Matthew A. (2022) Contribution of HLA and KIR Alleles to Systemic Sclerosis Susceptibility and Immunological and Clinical Disease Subtypes. Frontiers in Genetics, 13, Article number: 913196.

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Van Der Linden, Sjef M., Khan, Muhammad Asim, Li, Zhixiu, Baumberger, Heinz, Van Zandwijk, Hermine, Khan, Kazim, Villiger, Peter M., & Brown, Matthew A. (2022) Factors predicting axial spondyloarthritis among first-degree relatives of probands with ankylosing spondylitis: A family study spanning 35 years. Annals of the Rheumatic Diseases, 81(6), pp. 831-837.

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Hwang, Mark C., Lee, Min Jae, Gensler, Lianne S., Brown, Matthew A., Tahanan, Amirali, Rahbar, Mohammad H., Hunter, Theresa, Shan, Mingyan, Ishimori, Mariko L., Reveille, John D., Weisman, Michael H., & Learch, Thomas J. (2022) Identifying trajectories of radiographic spinal disease in ankylosing spondylitis: a 15-year follow-up study of the PSOAS cohort. Rheumatology (United Kingdom), 61(5), pp. 2079-2087.

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Stoll, Matthew L., Dequattro, Kimberly, Li, Zhixiu, Sawhney, Henna, Weiss, Pamela F., Nigrovic, Peter A., Wright, Tracey B., Schikler, Kenneth, Edelheit, Barbara, Morrow, Casey D., Reveille, John D., Brown, Matthew A., & Gensler, Lianne S. (2022) Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Children, 9(4), Article number: 569.

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Huang, Xiufeng & Brown, Matthew A. (2022) Progress in the genetics of uveitis. Genes and Immunity, 23(2), pp. 57-65.

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Mahil, Satveer K., Bechman, Katie, Raharja, Antony, Domingo-Vila, Clara, Baudry, David, Brown, Matthew A., Cope, Andrew P., Dasandi, Tejus, Graham, Carl, Khan, Hataf, Lechmere, Thomas, Malim, Michael H., Meynell, Freya, Pollock, Emily, Sychowska, Kamila, Barker, Jonathan N., Norton, Sam, Galloway, James B., Doores, Katie J., Tree, Timothy, & Smith, Catherine H. (2022) Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort study. The Lancet Rheumatology, 4(1), e42-e52.

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Li, Zhixiu, Van Der Linden, Sjef M., Khan, Muhammad Asim, Baumberger, Heinz, Zandwijk, Hermine Van, Khan, Mohammad Kazim, Villiger, Peter M., & Brown, Matthew A. (2022) Heterogeneity of axial spondyloarthritis: genetics, sex and structural damage matter. RMD Open, 8(1), Article number: e002302.

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McInerney-Leo, Aideen M., Chew, Hui Yi, Inglis, Po Ling, Leo, Paul J., Joseph, Shannon R., Cooper, Caroline L., Okano, Satomi, Hassall, Tim, Anderson, Lisa K., Bowman, Rayleen V., Gattas, Michael, Harris, Jessica E., Marshall, Mhairi S., Shaw, Janet G., Wheeler, Lawrie, Yang, Ian A., Brown, Matthew A., Fong, Kwun M., Simpson, Fiona, & Duncan, Emma L. (2021) Germline ERBB3 mutation in familial non-small-cell lung carcinoma: Expanding ErbB's role in oncogenesis. Human Molecular Genetics, 30(24), pp. 2393-2401.

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Williams, Camilla J., Li, Zhixiu, Harvey, Nicholas, Lea, Rodney A., Gurd, Brendon J., Bonafiglia, Jacob T., Papadimitriou, Ioannis, Jacques, Macsue, Croci, Ilaria, Stensvold, Dorthe, Wisloff, Ulrik, Taylor, Jenna L., Gajanand, Trishan, Cox, Emily R., Ramos, Joyce S., Fassett, Robert G., Little, Jonathan P., Francois, Monique E., Hearon, Christopher M., Sarma, Satyam, Janssen, Sylvan L.J.E., Van Craenenbroeck, Emeline M., Beckers, Paul, Cornelissen, Véronique A., Howden, Erin J., Keating, Shelley E., Yan, Xu, Bishop, David J., Bye, Anja, Haupt, Larisa M., Griffiths, Lyn R., Ashton, Kevin J., Brown, Matthew A., Torquati, Luciana, Eynon, Nir, & Coombes, Jeff S. (2021) Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study. Journal of Biomedical Science, 28, Article number: 37.

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Brown, Matthew A. & Li, Zhixiu (2021) Polygenic risk scores and rheumatic diseases. Chinese Medical Journal, 134(21), pp. 2521-2524.

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Mahil, S. K., Yates, Mark, Yiu, Z. Z.N., Langan, S. M., Tsakok, T., Dand, N., Mason, Kayleigh J., McAteer, H., Meynell, F., Coker, B., Vincent, A., Urmston, D., Vesty, A., Kelly, J., Lancelot, C., Moorhead, L., Bachelez, H., Capon, F., Contreras, C. R., De La Cruz, C., Di Meglio, P., Gisondi, P., Jullien, D., Lambert, J., Naldi, L., Norton, S., Puig, L., Spuls, P., Torres, T., Warren, R. B., Waweru, H., Weinman, J., Brown, M. A., Galloway, J. B., Griffiths, C. M., Barker, J. N., Smith, C. H., & other, and (2021) Describing the burden of the COVID-19 pandemic in people with psoriasis: findings from a global cross-sectional study. Journal of the European Academy of Dermatology and Venereology, 35(10), e636-e640.

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Li, Zhixiu, Wu, Xin, Leo, Paul J., De Guzman, Erika, Akkoc, Nurullah, Breban, Maxime, MacFarlane, Gary J., Mahmoudi, Mahdi, Marzo-Ortega, Helena, Anderson, Lisa K., Wheeler, Lawrie, Chou, Chung Tei, Harrison, Andrew A., Stebbings, Simon, Jones, Gareth T., Bang, So Young, Wang, Geng, Jamshidi, Ahmadreza, Farhadi, Elham, Song, Jing, Lin, Li, Li, Mengmeng, Wei, James Cheng Chung, Martin, Nicholas G., Wright, Margaret J., Lee, Min Jae, Wang, Yuqin, Zhan, Jian, Zhang, Jin San, Wang, Xiaobing, Jin, Zi Bing, Weisman, Michael H., Gensler, Lianne S., Ward, Michael M., Rahbar, Mohammad Hossein, Diekman, Laura, Kim, Tae Hwan, Reveille, John D., Wordsworth, Bryan Paul, Xu, Huji, & Brown, Matthew A. (2021) Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis. Annals of the Rheumatic Diseases, 80(9), pp. 1168-1174.

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Mahil, Satveer K., Bechman, Katie, Raharja, Antony, Domingo-Vila, Clara, Baudry, David, Brown, Matthew A., Cope, Andrew P., Dasandi, Tejus, Graham, Carl, Lechmere, Thomas, Malim, Michael H., Meynell, Freya, Pollock, Emily, Seow, Jeffery, Sychowska, Kamila, Barker, Jonathan N., Norton, Sam, Galloway, James B., Doores, Katie J., Tree, Timothy I.M., & Smith, Catherine H. (2021) The effect of methotrexate and targeted immunosuppression on humoral and cellular immune responses to the COVID-19 vaccine BNT162b2: a cohort study. The Lancet Rheumatology, 3(9), e627-e637.

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Graff, Sarah M., Johnson, Stephanie R., Leo, Paul J., Dadi, Prasanna K., Dickerson, Matthew T., Nakhe, Arya Y., McInerney-Leo, Aideen M., Marshall, Mhairi, Zaborska, Karolina E., Schaub, Charles M., Brown, Matthew A., Jacobson, David A., & Duncan, Emma L. (2021) A KCNK16 mutation causing TALK-1 gain of function is associated with maturity-onset diabetes of the young. JCI Insight, 6(13), Article number: e138057.

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Mauro, Daniele, Thomas, Ranjeny, Guggino, Giuliana, Lories, Rik, Brown, Matthew A., & Ciccia, Francesco (2021) Ankylosing spondylitis: an autoimmune or autoinflammatory disease? Nature Reviews Rheumatology, 17(7), pp. 387-404.

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Guggino, Giuliana, Mauro, Daniele, Rizzo, Aroldo, Alessandro, Riccardo, Raimondo, Stefania, Bergot, Anne Sophie, Rahman, M. Arifur, Ellis, Jonathan J., Milling, Simon, Lories, Rik, Elewaut, Dirk, Brown, Matthew A., Thomas, Ranjeny, & Ciccia, Francesco (2021) Inflammasome Activation in Ankylosing Spondylitis Is Associated With Gut Dysbiosis. Arthritis and Rheumatology, 73(7), pp. 1189-1199.

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Mahil, S. K., Yates, M., Langan, S. M., Yiu, Z. Z.N., Tsakok, T., Dand, N., Mason, K. J., McAteer, H., Meynell, F., Coker, B., Vincent, A., Urmston, D., Vesty, A., Kelly, J., Lancelot, C., Moorhead, L., Bachelez, H., Bruce, I. N., Capon, F., Contreras, C. R., Cope, A. P., De La Cruz, C., Di Meglio, P., Gisondi, P., Hyrich, K., Jullien, D., Lambert, J., Marzo-Ortega, H., McInnes, I., Naldi, L., Norton, S., Puig, L., Sengupta, R., Spuls, P., Torres, T., Warren, R. B., Waweru, H., Weinman, J., Griffiths, C. E.M., Barker, J. N., Brown, M. A., Galloway, J. B., Smith, C. H., & other, and (2021) Risk-mitigating behaviours in people with inflammatory skin and joint disease during the COVID-19 pandemic differ by treatment type: a cross-sectional patient survey. British Journal of Dermatology, 185(1), pp. 80-90.

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Hwang, Mark C., Lee, Min Jae, Gensler, Lianne S., Ward, Michael M., Brown, Matthew A., Learch, Thomas J., Tahanan, Amirali, Rahbar, Mohammad H., Ishimori, Mariko, Weisman, Michael H., Reveille, John D., & other, and (2021) Repeated Spinal Mobility Measures and Their Association With Radiographic Damage in Ankylosing Spondylitis. ACR Open Rheumatology, 3(6), pp. 413-421.

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Seabrook, Amanda J., Harris, Jessica E., Velosa, Sofia B., Kim, Edward, McInerney-Leo, Aideen M., Dwight, Trisha, Hockings, Jason I., Hockings, Nicholas G., Kirk, Judy, Leo, Paul J., Love, Amanda J., Luxford, Catherine, Marshall, Mhairi, Mete, Ozgur, Pennisi, David J., Brown, Matthew A., Gill, Anthony J., Hockings, Gregory I., Clifton-Bligh, Roderick J., & Duncan, Emma L. (2021) Multiple Endocrine Tumors Associated with Germline MAX Mutations: Multiple Endocrine Neoplasia Type 5? Journal of Clinical Endocrinology and Metabolism, 106(4), e1163-e1182.

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Nabais, Marta F., Lin, Tian, Benyamin, Beben, Williams, Kelly L., Garton, Fleur C., Vinkhuyzen, Anna A.E., Zhang, Futao, Vallerga, Costanza L., Restuadi, Restuadi, Freydenzon, Anna, Zwamborn, Ramona A.J., Hop, Paul J., Robinson, Matthew R., Gratten, Jacob, Visscher, Peter M., Hannon, Eilis, Mill, Jonathan, Brown, Matthew A., Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Needham, Merrilee, Veldink, Jan H., Mathers, Susan, Nicholson, Garth, Rowe, Dominic B., Henderson, Robert D., McCombe, Pamela A., Pamphlett, Roger, Yang, Jian, Blair, Ian P., McRae, Allan F., & Wray, Naomi R. (2020) Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. npj Genomic Medicine, 5(1), Article number: 10.

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Hildebrand, Joanne M., Kauppi, Maria, Majewski, Ian J., Liu, Zikou, Cox, Allison J., Miyake, Sanae, Petrie, Emma J., Silk, Michael A., Li, Zhixiu, Tanzer, Maria C., Brumatti, Gabriela, Young, Samuel N., Hall, Cathrine, Garnish, Sarah E., Corbin, Jason, Stutz, Michael D., Di Rago, Ladina, Gangatirkar, Pradnya, Josefsson, Emma C., Rigbye, Kristin, Anderton, Holly, Rickard, James A., Tripaydonis, Anne, Sheridan, Julie, Scerri, Thomas S., Jackson, Victoria E., Czabotar, Peter E., Zhang, Jian Guo, Varghese, Leila, Allison, Cody C., Pellegrini, Marc, Tannahill, Gillian M., Hatchell, Esme C., Willson, Tracy A., Stockwell, Dina, de Graaf, Carolyn A., Collinge, Janelle, Hilton, Adrienne, Silke, Natasha, Spall, Sukhdeep K., Chau, Diep, Athanasopoulos, Vicki, Metcalf, Donald, Laxer, Ronald M., Bassuk, Alexander G., Darbro, Benjamin W., Fiatarone Singh, Maria A., Vlahovich, Nicole, Hughes, David, Kozlovskaia, Maria, Ascher, David B., Warnatz, Klaus, Venhoff, Nils, Thiel, Jens, Biben, Christine, Blum, Stefan, Reveille, John, Hildebrand, Michael S., Vinuesa, Carola G., McCombe, Pamela, Brown, Matthew A., Kile, Benjamin T., McLean, Catriona, Bahlo, Melanie, Masters, Seth L., Nakano, Hiroyasu, Ferguson, Polly J., Murphy, James M., Alexander, Warren S., & Silke, John (2020) A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction. Nature Communications, 11(1), Article number: 3150.

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Demeshko, Anastassia, Pennisi, David J., Narayan, Sushil, Gray, Stacy W., Brown, Matthew A., & McInerney-Leo, Aideen M. (2020) Factors influencing cancer genetic somatic mutation test ordering by cancer physician. Journal of Translational Medicine, 18(1), Article number: 431.

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Liew, Jean W., Ward, Michael M., Reveille, John D., Weisman, Michael, Brown, Matthew A., Lee, Min Jae, Rahbar, Mohammed, Heckbert, Susan R., & Gensler, Lianne S. (2020) Nonsteroidal Antiinflammatory Drug Use and Association With Incident Hypertension in Ankylosing Spondylitis. Arthritis Care and Research, 72(11), pp. 1645-1652.

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Sternes, Peter R., Martin, Tammy M., Paley, Michael, Diamond, Sarah, Asquith, Mark J., Brown, Matthew A., & Rosenbaum, James T. (2020) HLA-A alleles including HLA-A29 affect the composition of the gut microbiome: a potential clue to the pathogenesis of birdshot retinochoroidopathy. Scientific Reports, 10, Article number: 17636.

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Brown, Matthew A., Xu, Huji, & Li, Zhixiu (2020) Genetics and the axial spondyloarthritis spectrum. Rheumatology (United Kingdom), 59(Supplement 4), IV58-IV66.

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Hanson, Aimee L., Vukcevic, Damjan, Leslie, Stephen, Harris, Jessica, Le Cao, Kim Anh, Kenna, Tony J., Brown, Matthew A., & other, and (2020) Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis. PLoS Genetics, 16(8), Article number: e1008906.

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Hanson, Aimee L., Nel, Hendrik J., Bradbury, Linda, Phipps, Julie, Thomas, Ranjeny, Lê Cao, Kim Anh, Kenna, Tony J., & Brown, Matthew A. (2020) Altered Repertoire Diversity and Disease-Associated Clonal Expansions Revealed by T Cell Receptor Immunosequencing in Ankylosing Spondylitis Patients. Arthritis and Rheumatology, 72(8), pp. 1289-1302.

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Brown, Matthew A., Li, Zhixiu, & Cao, Kim Anh Lê (2020) Biomarker development for axial spondyloarthritis. Nature Reviews Rheumatology, 16(8), pp. 448-463.

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Watad, Abdulla, Rowe, Hannah, Russell, Tobias, Zhou, Qiao, Anderson, Lisa K, Khan, Almas, Dunsmuir, Robert, Loughenbury, Peter, Borse, Vishal, Rao, Abhay, Millner, Peter A, Bragazzi, Nicola Luigi, Amital, Howard, Cuhtbert, Richard, Wittmann, Miriam, Sharif, Kassem, Kenna, Tony, Brown, Matthew A, Newton, Darren, Bridgewood, Charlie, & Mcgonagle, Dennis G (2020) Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression. Annals of the Rheumatic Diseases, 79(8), pp. 1044-1054.

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D'Urso, Shannon, Rajbhandari, Dorrilyn, Peach, Elizabeth, De Guzman, Erika, Li, Qiang, Medland, Sarah E., Gordon, Scott D., Martin, Nicholas G., Ligthart, Symen, Brown, Matthew A., Powell, Joseph, McArthur, Colin, Rhodes, Andrew, Meyer, Jason, Finfer, Simon, Myburgh, John, Blumenthal, Antje, Cohen, Jeremy, Venkatesh, Balasubramanian, Cuellar-Partida, Gabriel, & Evans, David M. (2020) Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis. Twin Research and Human Genetics, 23(4), pp. 204-213.

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Rostami, S., Hoff, M., Brown, M. A., Hveem, K., & Videm, V. (2020) Comparison of methods to construct a genetic risk score for prediction of rheumatoid arthritis in the population-based Nord-Trondelag Health Study, Norway. Rheumatology (United Kingdom), 59(7), pp. 1743-1751.

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Hwang, Mark C., Lee, Min Jae, Gensler, Lianne S., Ward, Michael M., Brown, Matthew A., Eisen, Seth, Learch, Thomas J., Tahanan, Amirali, Rahbar, Mohammad H., Ishimori, Mariko L., Weisman, Michael H., & Reveille, John D. (2020) Longitudinal associations between depressive symptoms and clinical factors in ankylosing spondylitis patients: analysis from an observational cohort. Rheumatology International, 40(7), pp. 1053-1061.

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Shi, Xiu Yu, Wang, Geng, Li, Ting, Li, Zhixiu, Leo, Paul, Liu, Zhisheng, Wu, Gefei, Zhu, Hongmin, Zhang, Yuqin, Li, Dong, Gao, Li, Yang, Liu, Wang, Wei, Liao, Jianxiang, Wang, Jiwen, Zhou, Shuizhen, Wang, Hua, Li, Xiaojing, Gao, Jingyun, Zhang, Li, Shu, Xiaomei, Li, Dan, Li, Yan, Chen, Chunhong, Zhang, Xiuju, Partida, Gabriel Cuellar, Lundberg, Mischa, Reutens, David, Bartlett, Perry, Brown, Matthew A., Zou, Li Ping, & Xu, Huji (2020) Identification of susceptibility variants to benign childhood epilepsy with centro-temporal spikes (BECTS) in Chinese Han population. EBioMedicine, 57, Article number: 102840.

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Khalilidehkordi, Elham, Clarke, Laura, Arnett, Simon, Bukhari, Wajih, Jimenez Sanchez, Sofia, O'Gorman, Cullen, Sun, Jing, Prain, Kerri M., Woodhall, Mark, Silvestrini, Roger, Bundell, Christine S., Abernethy, David, Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J., Brown, Matthew, Brownlee, Wallace, Butzkueven, Helmut, Carroll, William M., Chen, Celia, Coulthard, Alan, Dale, Russell C., Das, Chandi, Fabis-Pedrini, Marzena J., Fulcher, David, Gillis, David, Hawke, Simon, Heard, Robert, Henderson, Andrew P.D., Heshmat, Saman, Hodgkinson, Suzanne, Kilpatrick, Trevor J., King, John, Kneebone, Chris, Kornberg, Andrew J., Lechner-Scott, Jeannette, Lin, Ming Wei, Lynch, Christopher, Macdonell, Richard A.L., Mason, Deborah F., McCombe, Pamela A., Pereira, Jennifer, Pollard, John D., Ramanathan, Sudarshini, Reddel, Stephen W., Shaw, Cameron, Spies, Judith, Stankovich, James, Sutton, Ian, Vucic, Steve, Walsh, Michael, Wong, Richard C., Yiu, Eppie M., Barnett, Michael H., Kermode, Allan G., Marriott, Mark P., Parratt, John, Slee, Mark, Taylor, Bruce V., Willoughby, Ernest, Brilot, Fabienne, Vincent, Angela, Waters, Patrick, & Broadley, Simon A. (2020) Relapse Patterns in NMOSD: Evidence for Earlier Occurrence of Optic Neuritis and Possible Seasonal Variation. Frontiers in Neurology, 11, Article number: 537.

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Huang, Xiu Feng, Li, Zhixiu, de Guzman, Erika, Robinson, Philip, Gensler, Lianne, Ward, Michael M., Rahbar, Mohammad Hossein, Lee, Min Jae, Weisman, Michael H., MacFarlane, Gary J., Jones, Gareth T., Klingberg, Eva, Forsblad-D’Elia, Helena, McCluskey, Peter, Wakefield, Denis, Coombes, Jeff S., Fiatarone Singh, Maria A., Mavros, Yorgi, Vlahovich, Nicole, Hughes, David C., Marzo-Ortega, Helena, van der Horste-Bruinsma, Irene, O’Shea, Finbar, Martin, Tammy M., Rosenbaum, James, Breban, Maxime, Jin, Zi Bing, Leo, Paul, Reveille, John D., Wordsworth, B. Paul, & Brown, Matthew A. (2020) Genomewide association study of acute anterior uveitis identifies new susceptibility loci. Investigative Ophthalmology and Visual Science, 61(6), Article number: 3.

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Gresle, Melissa M., Jordan, Margaret A., Stankovich, Jim, Spelman, Tim, Johnson, Laura J., Laverick, Louise, Hamlett, Alison, Smith, Letitia D., Jokubaitis, Vilija G., Baker, Josephine, Haartsen, Jodi, Taylor, Bruce, Charlesworth, Jac, Bahlo, Melanie, Speed, Terence P., Brown, Matthew A., Field, Judith, Baxter, Alan G., & Butzkueven, Helmut (2020) Multiple sclerosis risk variants regulate gene expression in innate and adaptive immune cells. Life Science Alliance, 3(7), Article number: e202000650.

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McInerney-Leo, Aideen M., West, Jennifer, Meiser, Bettina, West, Malcolm, Brown, Matthew A., & Duncan, Emma (2020) Causal Attributions in an Australian Aboriginal Family With Marfan Syndrome: A Qualitative Study. Frontiers in Genetics, 11, Article number: 461.

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Wang, Geng, Kim, Tae Hwan, Li, Zhixiu, Cortes, Adrian, Kim, Kwangwoo, Bang, So Young, Leo, Paul, Brown, Matthew A., & Xu, Huji (2020) MHC associations of ankylosing spondylitis in East Asians are complex and involve non-HLA-B27 HLA contributions. Arthritis Research and Therapy, 22(1), Article number: 74.

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McInerney-Leo, Aideen M., West, Jennifer, Wheeler, Lawrie, Leo, Paul J., Summers, Kim M., Anderson, Lisa, Brown, Matthew A., West, Malcolm, & Duncan, Emma L. (2020) Compound heterozygous mutations in FBN1 in a large family with Marfan syndrome. Molecular Genetics and Genomic Medicine, 8(3), Article number: e1116.

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Rostami, Sina, Hoff, Mari, Brown, Matthew A., Hveem, Kristian, Holmen, Oddgeir L., Fritsche, Lars G., & Videm, Vibeke (2020) Prediction of ankylosing spondylitis in the HUNT study by a genetic risk score combining 110 single-nucleotide polymorphisms of genome-wide significance. Journal of Rheumatology, 47(2), pp. 204-210.

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Duffy, David L., Jagirdar, Kasturee, Lee, Katie J., McWhirter, Seamus R., McMeniman, Erin K., De'Ambrosis, Brian, Pflugfelder, Annette, Rayner, Jenna E., Whiteman, David C., Brown, Matthew A., Martin, N. G., Smithers, B. M., Schaider, Helmut, Soyer, H. Peter, & Sturm, Richard A. (2020) Genes Determining Nevus Count and Dermoscopic Appearance in Australian Melanoma Cases and Controls. Journal of Investigative Dermatology, 140(2), 498-501.e17.

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Lee, Minjae, Rahbar, Mohammad H., Gensler, Lianne S., Brown, Matthew, Weisman, Michael, & Reveille, John D. (2020) A latent class based imputation method under Bayesian quantile regression framework using asymmetric Laplace distribution for longitudinal medication usage data with intermittent missing values. Journal of Biopharmaceutical Statistics, 30(1), pp. 160-177.

2

Gregson, Celia L., Bergen, Dylan J.M., Leo, Paul, Sessions, Richard B., Wheeler, Lawrie, Hartley, April, Youlten, Scott, Croucher, Peter I., McInerney-Leo, Aideen M., Fraser, William, Tang, Jonathan C.Y., Anderson, Lisa, Marshall, Mhairi, Sergot, Leon, Paternoster, Lavinia, Davey Smith, George, Brown, Matthew A., Hammond, Chrissy, Kemp, John P., Tobias, Jon H., Duncan, Emma L., & other, and (2020) A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD-Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis. Journal of Bone and Mineral Research, 35(1), pp. 92-105.

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Broadhouse, Kathryn M., Singh, Maria Fiatarone, Suo, Chao, Gates, Nicola, Wen, Wei, Brodaty, Henry, Jain, Nidhi, Wilson, Guy C., Meiklejohn, Jacinda, Singh, Nalin, Baune, Bernhard T., Baker, Michael, Foroughi, Nasim, Wang, Yi, Kochan, Nicole, Ashton, Kevin, Brown, Matt, Li, Zhixiu, Mavros, Yorgi, Sachdev, Perminder S., & J.Valenzuela, Michael (2020) Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI. NeuroImage: Clinical, 25, Article number: 102182.

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Yin, Jian, Sternes, Peter, Wang, Mingbang, Song, Jing, Morrison, Mark, Li, Ting, Zhou, Ling, Wu, Xin, He, Fusheng, Zhu, Jian, Brown, Matt, & Xu, Huji (2020) Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy upon microbiome composition. Annals of the Rheumatic Diseases, 79(1), pp. 132-140.

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Huang, Xiu Feng, Sun, Li, Zhang, Chunwu, Zhou, Zhenni, Chen, Hui, Zhang, Linhua, Brown, Matthew A., & Xia, Xiaoru (2020) Whole-Exome Sequencing Reveals a Rare Missense Variant in SLC16A9 in a Pedigree with Early-Onset Gout. BioMed Research International, 2020, Article number: 4321419.

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Lopez-Isac, Elena, Acosta-Herrera, Marialbert, Kerick, Martin, Assassi, Shervin, Satpathy, Ansuman T., Granja, Jeffrey, Mumbach, Maxwell R., Beretta, Lorenzo, Simeon, Carmen P., Carreira, Patricia, Ortego-Centeno, Norberto, Castellvi, Ivan, Bossini-Castillo, Lara, Carmona, F. David, Orozco, Gisela, Hunzelmann, Nicolas, Distler, Jörg H.W., Franke, Andre, Lunardi, Claudio, Moroncini, Gianluca, Gabrielli, Armando, de Vries-Bouwstra, Jeska, Wijmenga, Cisca, Koeleman, Bobby P.C., Nordin, Annika, Padyukov, Leonid, Hoffmann-Vold, Anna Maria, Lie, Benedicte, Ríos, R., Callejas, J. L., Vargas-Hitos, J. A., García-Portales, R., Camps, M. T., Fernández-Nebro, A., González-Escribano, M. F., García-Hernández, F. J., Castillo, M. J., Aguirre, M. A., Gómez-Gracia, I., Fernández-Gutiérrez, B., Rodríguez-Rodríguez, L., García de la Peña, P., Vicente, E., Andreu, J. L., Fernández de Castro, M., López-Longo, F. J., Martínez, L., Fonollosa, Guillén, A., Espinosa, G., Tolosa, C., Pros, A., Rodríguez-Carballeira, M., Narváez, F. J., Rubio-Rivas, M., Ortiz-Santamaría, Madroñero, A. B., González-Gay, M. A., Díaz, B., Trapiella, L., Sousa, A., Egurbide, M. V., Fanlo-Mateo, P., Sáez-Comet, L., Díaz, F., Hernández, Beltrán, E., Román-Ivorra, J. A., Grau, E., Alegre-Sancho, J. J., Freire, M., Blanco-García, F. J., Oreiro, N., Witte, T., Kreuter, A., Riemekasten, G., Airó, P., Magro, C., Voskuyl, A. E., Vonk, M. C., Hesselstrand, R., Proudman, Susanna, Stevens, Wendy, Nikpour, Mandana, Zochling, J., Sahhar, J., Roddy, J., Nash, P., Tymms, K., Rischmueller, M., Lester, S., Vyse, Timothy, Herrick, Ariane L., Worthington, Jane, Denton, Christopher P., Allanore, Yannick, Brown, Matthew A., Radstake, Timothy R.D.J., Fonseca, Carmen, Chang, Howard Y., Mayes, Maureen D., Martin, Javier, & other, and (2019) GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways. Nature Communications, 10(1), Article number: 4955.

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Periyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Vinkhuyzen, Anna, McRae, Allan, Holliday, Elizabeth G., Nyholt, Dale R., Nancarrow, Derek, Bakshi, Andrew, Hemani, Gibran, Nertney, Deborah, Smith, Heather, Filippich, Cheryl, Patel, Kalpana, Fowdar, Javed, McLean, Duncan, Tirupati, Srinivasan, Nagasundaram, Arunkumar, Gundugurti, Prasad Rao, Selvaraj, Krishnamurthy, Jegadeesan, Jayaprakash, Jorde, Lynn B., Wray, Naomi R., Brown, Matthew A., Suetani, Rachel, Giacomotto, Jean, Thara, Rangaswamy, & Mowry, Bryan J. (2019) Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study. JAMA Psychiatry, 76(10), pp. 1026-1034.

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Gorvin, Caroline M., Loh, Nellie Y., Stechman, Michael J., Falcone, Sara, Hannan, Fadil M., Ahmad, Bushra N., Piret, Sian E., Reed, Anita A.C., Jeyabalan, Jeshmi, Leo, Paul, Marshall, Mhairi, Sethi, Siddharth, Bass, Paul, Roberts, Ian, Sanderson, Jeremy, Wells, Sara, Hough, Tertius A., Bentley, Liz, Christie, Paul T., Simon, Michelle M., Mallon, Ann Marie, Schulz, Herbert, Cox, Roger D., Brown, Matthew A., Huebner, Norbert, Brown, Steve D., & Thakker, Rajesh V. (2019) Mice with a Brd4 Mutation Represent a New Model of Nephrocalcinosis. Journal of Bone and Mineral Research, 34(7), pp. 1324-1335.

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Whyte, Jessica, Ellis, Jonathan, Brown, Matt, & Kenna, Tony (2019) Best practices in DNA methylation: lessons from inflammatory bowel disease, psoriasis and ankylosing spondylitis. Arthritis Research and Therapy, 21(1), Article number: 133 1-14.

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Brown, Matthew A. & Leo, Paul J. (2019) Genetic susceptibility to cervical neoplasia. Papillomavirus Research, 7, pp. 132-134.

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Hsiao, Edward C., Di Rocco, Maja, Cali, Amanda, Zasloff, Michael, Al Mukaddam, Mona, Pignolo, Robert J., Grunwald, Zvi, Netelenbos, Coen, Keen, Richard, Baujat, Genevieve, Brown, Matthew A., Cho, Tae Joon, De Cunto, Carmen, Delai, Patricia, Haga, Nobuhiko, Morhart, Rolf, Scott, Christiaan, Zhang, Keqin, Diecidue, Robert J., Friedman, Clive S., Kaplan, Fredrick S., & Eekhoff, Elisabeth M.W. (2019) Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP). British Journal of Clinical Pharmacology, 85(6), pp. 1199-1207.

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Pignolo, Robert J., Baujat, Geneviève, Brown, Matthew A., De Cunto, Carmen, Dirocco, Maja, Hsiao, Edward C., Keen, Richard, Al Mukaddam, Mona, Sang, Kim Hanh Le Quan, Wilson, Amy, White, Barbara, Grogan, Donna R., & Kaplan, Frederick S. (2019) Natural history of fibrodysplasia ossificans progressiva: Cross-sectional analysis of annotated baseline phenotypes. Orphanet Journal of Rare Diseases, 14(1), Article number: 98.

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Johnson, Stephanie R., Carter, Hannah E., Leo, Paul J., Hollingworth, Samantha, Davis, Elizabeth, Jones, Timothy W., Conwell, Louise S., Harrison, Mark D., Brown, Matthew A., Graves, Nicholas, & Duncan, Emma L. (2019) Response to comment on Johnson et al. Cost-effectiveness analysis of routine screening using massively parallel sequencing for maturity-onset diabetes of the young in a pediatric diabetes cohort: Reduced health system costs and improved patient quality of life. Diabetes Care 2019;42:69-76. Diabetes Care, 42(5), e79-e80.

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Gorvin, Caroline, Ahmad, Bushra, Stechman, Michael, Loh, Nellie, Hough, Tertius, Leo, Paul, Clout, Mhairi, Sethi, Siddharth, Bentley, Liz, Piret, Sian, Reed, Anita, Jeyabalan, Jeshmi, Christie, Paul, Wells, Sara, Simon, Michelle, Mallon, Ann-Marie, Schulz, Herbert, Huebner, Norbert, Brown, Matt, Cox, Roger, Brown, Steve, & Thakker, Rajesh (2019) An N-ethyl-N-nitrosourea (ENU)-induced Tyr265Stop mutation of the DNA polymerase accessory subunit gamma 2 (Polg2) is associated with renal calcification in mice. Journal of Bone and Mineral Research, 34(3), pp. 497-507.

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Gonzalez-Serna, David, Lopez-Isac, Elena, Yilmaz, Neslihan, Gharibdoost, Farhad, Jamshidi, Ahmadreza, Kavosi, Hoda, Poursani, Shiva, Farsad, Faraneh, Direskeneli, Haner, Saruhan-Direskeneli, Guhrer, Vargas, Sofia, Sawalha, Amr, Brown, Matt, Yavuz, Sule, Mahmoudi, Mahdi, & Martin, Javier (2019) Analysis of the genetic component of systemic sclerosis in Iranian and Turkish populations through a genome-wide association study. Rheumatology, 58(2), pp. 289-298.

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Johnson, Stephanie, Ellis, Jonathan, Leo, Paul, Anderson, Lisa, Ganti, Uma, Harris, Jessica, Curran, Jacqueline, McInerney-Leo, Aideen, Paramalingam, Nirubasini, Song, Sharon, Conwell, Louise, Harris, Mark, Jones, Timothy, Brown, Matt, Davis, Elizabeth, & Duncan, Emma (2019) Comprehensive genetic screening: The prevalence of maturity-onset diabetes of the young gene variants in a population-based childhood diabetes cohort. Pediatric Diabetes, 20(1), pp. 57-64.

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Johnson, Stephanie, Carter, Hannah, Leo, Paul, Hollingworth, Samantha, Davis, Elizabeth, Jones, Timothy, Conwell, Louise, Harris, Mark, Brown, Matt, Graves, Nicholas, & Duncan, Emma (2019) Cost-effectiveness analysis of routine screening using massively parallel sequencing for maturity-onset diabetes of the young in a pediatric diabetes cohort: Reduced health system costs and improved patient quality of life. Diabetes Care, 42(1), pp. 69-76.

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Brown, Matt, Xu, Huji, & Reveille, John (2019) Genetics of axial spondyloarthritis. In Khan, M & Mease, P (Eds.) Axial spondyloarthritis. Elsevier, United States of America, pp. 67-85.

4

Li, Zhixiu, Akar, Servet, Yarkan, Handan, Lee, Sau Kuen, Cetin, Pınar, Can, Gercek, Kenar, Gokce, Capa, Fernur, Pamuk, Omer Nuri, Pehlivan, Yavuz, Cremin, Katie, de Guzman, Erika, Harris, Jessica, Wheeler, Lawrie, Jamshidi, Ahmadreza, Vojdanian, Mahdi, Farhadi, Elham, Ahmadzadeh, Nooshin, Yüce, Zeynep, Dalkılıc, Ediz, Solmaz, Dilek, Akın, Berrin, Donmez, Salim, Sarı, İsmail, Leo, Paul J., Kenna, Tony J., Onen, Fatos, Mahmoudi, Mahdi, Brown, Matthew A., & Akkoc, Nurullah (2019) Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis. PLoS Genetics, 15(4), Article number: e1008038.

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Reveille, John, Zhou, Xiaodong, Lee, MinJae, Weisman, Michael, Yi, Lin, Gensler, Lianne, Zou, Hejian, Ward, Michael, Ishimori, Mariko, Learch, Thomas, He, Dongyi, Rahbar, Mohammad, Wang, Jiucun, & Brown, Matt (2019) HLA class I and II alleles in susceptibility to ankylosing spondylitis. Annals of the Rheumatic Diseases, 78(1), pp. 66-73.

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Sternes, Peter & Brown, Matt (2019) The gut microbiome and ankylosing spondylitis. In Khan, M & Mease, P (Eds.) Axial spondyloarthritis. Elsevier, United States of America, pp. 87-95.

5

Liu, Zhenwei, Li, Fengxia, Pan, Axiao, Xue, Huangqi, Jiang, Shan, Zhu, Chengwei, Jin, Mengmeng, Fang, Jinxia, Zhu, Xiaochun, Brown, Matthew A., & Wang, Xiaobing (2019) Elevated CCL19/CCR7 Expression During the Disease Process of Primary Sjogren's Syndrome. Frontiers in Immunology, 10, Article number: 795.

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Asquith, Mark, Sternes, Peter, Costello, Mary-Ellen, Karstens, Lisa, Diamond, Sarah, Martin, Tammy, Li, Zhixiu, Clout, Mhairi, Spector, Timothy, Le Cao, Kim-Anh, Rosenbaum, James, & Brown, Matt (2019) HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome. Arthritis and Rheumatology, 71(10), pp. 1642-1650.

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Roberts, Rebecca, Wallace, Mary, Harrison, Andrew, White, Douglas, Dalbeth, Nicola, Stamp, Lisa, Ching, Daniel, Highton, John, Merriman, Tony, Robinson, Philip, Brown, Matt, & Stebbings, Simon (2018) Association of Crohn's disease-related chromosome 1q32 with ankylosing spondylitis is independent of bowel symptoms and faecal calprotectin. PeerJ, 6, Article number: e5088 1-11.

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Johnson, Stephanie, Leo, Paul, Conwell, Louise, Harris, Mark, Brown, Matt, & Duncan, Emma (2018) Clinical usefulness of comprehensive genetic screening in maturity onset diabetes of the young (MODY): A novel ABCC8 mutation in a previously screened family. Journal of Diabetes, 10(9), pp. 764-767.

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11

Mullaney, Jane A., Stephens, Juliette E., Costello, Mary-Ellen, Fong, Cai, Geeling, Brooke E., Gavin, Patrick G., Wright, Casey M., Spector, Timothy D., Brown, Matthew A., & Hamilton-Williams, Emma E. (2018) Correction to: Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota. Microbiome, 6, Article number-51.

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Leo, Paul J., Madeleine, Margaret M., Wang, Sophia, Schwartz, Stephen M., Newell, Felicity, Pettersson-Kymmer, Ulrika, Hemminki, Kari, Hallmans, Goran, Tiews, Sven, Steinberg, Winfried, Rader, Janet S., Castro, Felipe, Safaeian, Mahboobeh, Franco, Eduardo L., Coutl�e, Fran�ois, Ohlsson, Claes, Cortes, Adrian, Marshall, Mhairi, Mukhopadhyay, Pamela, Cremin, Katie, Johnson, Lisa G., Trimble, Cornelia L., Garland, Suzanne, Tabrizi, Sepehr N., Wentzensen, Nicolas, Sitas, Freddy, Little, Julian, Cruickshank, Maggie, Frazer, Ian H., Hildesheim, Allan, & Brown, Matthew A. (2018) Correction: Defining the genetic susceptibility to cervical neoplasia—A genome-wide association study. PLoS Genetics, 14(3), e1007257-e1007257.

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Bradbury, Linda, Hollis, Kelly, Gautier, Benoit, Shankaranarayana, Sateesh, Robinson, Philip, Saad, Nivene, Lê Cao, Kim-Anh, & Brown, Matt (2018) Diffusion-weighted imaging is a sensitive and specific magnetic resonance sequence in the diagnosis of ankylosing spondylitis. Journal of Rheumatology, 45(6), pp. 771-778.

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Brown, Matt, Bird, Paul, Robinson, Philip, Mease, Philip, van den Bosch, Filip, Surian, Christine, Jones, Heather, Szumski, Annette, Marshall, Lisa, Wiid, Zirke, & Dougados, Maxime (2018) Evaluation of the effect of baseline MRI sacroiliitis and C reactive protein status on etanercept treatment response in non-radiographic axial spondyloarthritis: a post hoc analysis of the EMBARK study. Annals of the Rheumatic Diseases, 77(7), pp. 1090-1093.

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Vecellio, Matteo, Cortes, Adrian, Roberts, Amity, Ellis, Jonathan, Cohen, Carla, Knight, Julian, Brown, Matt, Bowness, Paul, & Wordsworth, Paul (B.P.) (2018) Evidence for a second ankylosing spondylitis-associated RUNX3 regulatory polymorphism. RMD Open, 4(1), Article number: e000628 1-10.

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Neal, Mantick, Bachman, Eric, Baujat, Genevieve, Brown, Matt, Collins, Oliver, De Cunto, Carmen, Delai, Patricia, Eekhoff, Marelise, zum Felde, Roger, Grogan, Donna, & other, and (2018) The FOP Connection Registry: Design of an international patient-sponsored registry for Fibrodysplasia Ossificans Progressiva. Bone, 109, pp. 285-290.

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Hanson, Aimee, Cuddihy, Thomas, Haynes, Katelin, Loo, Dorothy, Morton, Craig, Oppermann, Udo, Leo, Paul, Thomas, Gethin, Le Cao, Kim-Anh, Kenna, Tony, & Brown, Matt (2018) Genetic variants in ERAP1 and ERAP2 associated with immune-mediated diseases influence protein expression and the isoform profile. Arthritis and Rheumatology, 70(2), pp. 255-265.

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Duncan, Emma & Brown, Matt (2018) Genome-wide association studies. In Whyte, M, Eisman, J, Thakker, R, & Igarashi, T (Eds.) Genetics of bone biology and skeletal disease (2nd Edition). Academic Press, United Kingdom, pp. 33-41.

3

Graham, Patricia, Kaidonis, Georgia, Abhary, Sotoodeh, Gillies, Mark, Daniell, Mark, Essex, Rohan, Chang, John, Lake, Stewart, Pal, Bishwanath, Jenkins, Alicia, Hewitt, Alex, Lamoureux, Ecosse, Hykin, Philip, Petrovsky, Nikolai, Brown, Matt, Craig, Jamie, & Burdon, Kathryn (2018) Genome-wide association studies for diabetic macular edema and proliferative diabetic retinopathy. BMC Medical Genetics, 19, Article number: 71.

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Blum, Stefan, Ji, Ying, Pennisi, David, Li, Zhixiu, Leo, Paul, McCombe, Pamela, & Brown, Matt (2018) Genome-wide association study in Guillain-Barre syndrome. Journal of Neuroimmunology, 323, pp. 109-114.

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Gregson, Celia, Newell, Felicity, Leo, Paul, Clark, Graeme, Paternoster, Lavinia, Clout, Mhairi, Forgetta, Vincenzo, Morris, John, Ge, Bing, Bao, Xiao, Bassett, J.H. Duncan, Williams, Graham, Youlten, Scott, Croucher, Peter, Smith, George Davey, Evans, David, Kemp, John, Brown, Matt, Tobias, Jonathan, & Duncan, Emma (2018) Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes. Bone, 114, pp. 62-71.

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Bao, Xiao, Hanson, Aimee, Madeleine, Margaret, Wang, Sophia, Schwartz, Stephen, Newell, Felicity, Pettersson-Kymmer, Ulrika, Hemminki, Kari, Tiews, Sven, Steinberg, Winfried, Clout, Mhairi, Brown, Matt, Duncan, Emma, & Leo, Paul (2018) HLA and KIR associations of cervical neoplasia. Journal of Infectious Diseases, 218(12), pp. 2003-2015.

26

Rahbar, Mohammad, Lee, MinJae, Hessabi, Manouchehr, Tahanan, Amirali, Brown, Matt, Learch, Thomas, Diekman, Laura, Weisman, Michael, & Reveille, John (2018) Harmonization, data management, and statistical issues related to prospective multicenter studies in Ankylosing spondylitis (AS): Experience from the Prospective Study Of Ankylosing Spondylitis (PSOAS) cohort. Contemporary Clinical Trials Communications, 11, pp. 127-135.

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Alonso, Nerea, Estrada, Karol, Albagha, Omar, Herrera, Lizbeth, Reppe, Sjur, Olstad, Ole, Gautvik, Kaare, Ryan, Niamh, Evans, Kathryn, Nielson, Carrie, Brown, Matt, Duncan, Emma, & other, and (2018) Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density. Annals of the Rheumatic Diseases, 77(3), pp. 378-385.

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Cortes, Adrian, Gladman, Dafna, Raychaudhuri, Soumya, Cui, Jing, Wheeler, Lawrie, & Brown, Matt (2018) Imputation-based analysis of MICA alleles in the susceptibility to ankylosing spondylitis (Letter). Annals of the Rheumatic Diseases, 77(11), pp. 1691-1692.

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De Smit, Elisabeth, Lukowski, Samuel, Anderson, Lisa, Senabouth, Anne, Dauyey, Kaisar, Song, Sharon, Wyse, Bruce, Wheeler, Lawrie, Chen, Christine, Cao, Khoa, Brown, Matt, & other, and (2018) Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis. BMC Medical Genomics, 11, Article number: 61 1-16.

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Esapa, Christopher, Piret, Sian, Nesbit, M. Andrew, Thomas, Gethin, Coulton, Leslie, Gallagher, Orla, Simon, Michelle, Kumar, Saumya, Mallon, Ann-Marie, Bellantuono, Ilaria, Brown, Matt, Croucher, Peter, Potter, Paul, Brown, Steve, Cox, Roger, & Thakker, Rajesh (2018) An N-ethyl-N-nitrosourea (ENU) mutagenized mouse model for autosomal dominant nonsyndromic kyphoscoliosis due to vertebral fusion. JBMR Plus, 2(3), pp. 154-163.

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Santos, Margarida, Couto, Ana, Foroni, Iris, Bettencourt, Bruno, Li, Zhixiu, Meneses, Raquel, Wheeler, Lawrie, Pereira, Joaquim, Pimentel-Santos, Fernando Manuel, Fonseca, Joao Eurico, Alves, Helena, Martinho, Antonio, Lima, Manuela, Brown, Matt, & Bruges-Armas, Jacome (2018) Non-classical human leucocyte antigens in ankylosing spondylitis: possible association with HLA-E and HLA-F. RMD Open, 4(1), Article number: e000677 1-9.

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Duffy, David, Zhu, Gu, Sanna, Marianna, Iles, Mark, Jacobs, Leonie, Evans, David, Yazar, Seyhan, Beesley, Jonathan, Law, Matthew, Kraft, Peter, Brown, Matthew, & other, and (2018) Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nature Communications, 9, Article number: 4774 1-10.

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Dau, Jonathan, Lee, MinJae, Ward, Michael, Gensler, Lianne, Brown, Matt, Learch, Thomas, Diekman, Laura, Tahanan, Amirali, Rahbar, Mohammad, Weisman, Michael, & Reveille, John (2018) Opioid analgesic use in patients with ankylosing spondylitis: An analysis of the prospective study of outcomes in an ankylosing spondylitis cohort. Journal of Rheumatology, 45(2), pp. 188-194.

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McInerney-Leo, Aideen, Wheeler, Lawrie, Sturm, Richard, Tan, Jean-Marie, Harris, Jessica, Anderson, Lisa, Jagirdar, Kasturee, Brown, Matt, Leo, Paul, Soyer, H. Peter, & Duncan, Emma (2018) Point mutation in p14ARF-specific exon 1Beta of CDKN2A causing familial melanoma and astrocytoma (Research Letter). British Journal of Dermatology, 178(4), e263-e264.

3

2

Ze Ya Maung, Kyaw, Leo, Paul, Bassal, Mahmoud, Casolari, Debora, Gray, James, Bray, Sarah, Pederson, Stephen, Singhal, Deepak, Samaraweera, Saumya, Nguyen, Tran, Cildir, Gokhan, Clout, Mhairi, Ewing, Adam, Duncan, Emma, Brown, Matt, Saal, Russell, & other, and (2018) Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia. Blood Cancer Journal, 8, Article number: 50 1-5.

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Brown, Matt (2018) Solving the pathogenesis of ankylosing spondylitis. Clinical Immunology, 186, pp. 46-50.

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Mullaney, Jane, Stephens, Juliette, Costello, Mary-Ellen, Fong, Cai, Geeling, Brooke, Gavin, Patrick, Wright, Casey, Spector, Timothy, Brown, Matt, & Hamilton-Williams, Emma (2018) Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota. Microbiome, 6, Article number: 35 1-16.

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Johnson, Stephanie, Leo, Paul, McInerney-Leo, Aideen, Anderson, Lisa, Clout, Mhairi, McGown, Ivan, Newell, Felicity, Brown, Matt, Conwell, Louise, Harris, Mark, & Duncan, Emma (2018) Whole-exome sequencing for mutation detection in pediatric disorders of insulin secretion: Maturity onset diabetes of the young and congenital hyperinsulinism. Pediatric Diabetes, 19(4), pp. 656-662.

14

10

Lee, MinJae, Rahbar, Mohammad, Brown, Matt, Gensler, Lianne, Weisman, Michael, Diekman, Laura, & Reveille, John (2018) A multiple imputation method based on weighted quantile regression models for longitudinal censored biomarker data with missing values at early visits. BMC Medical Research Methodology, 18, Article number: 8 1-12.

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Couto, Ana Rita, Parreira, Bruna, Thomson, Russell, Soares, Marta, Power, Deborah M., Stankovich, Jim, Armas, Jácome Bruges, & Brown, Matthew A. (2017) Combined approach for finding susceptibility genes in DISH/chondrocalcinosis families: Whole-genome-wide linkage and IBS/IBD studies. Human Genome Variation, 4, Article number: 17041.

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De Smit, Elisabeth, Clarke, Linda, Sanfilippo, Paul G, Merriman, Tony R, Brown, Matthew A, Hill, Catherine L, & Hewitt, Alex W (2017) Geo-epidemiology of temporal artery biopsy-positive giant cell arteritis in Australia and New Zealand: is there a seasonal influence? RMD Open, 3(2), Article number: e000531.

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Carter, H.E., Hollingworth, S., Duncan, E.L., Brown, M.A., Davis, E., Graves, N., & Johnson, S.R. (2017) Cost-effectiveness of genetic screening for maturity onset diebetes of the young (Mody). Value in Health, 20(5), A171-A172.

Visscher, Peter, Wray, Naomi, Zhang, Qian, Sklar, Pamela, McCarthy, Mark, Brown, Matt, & Yang, Jian (2017) 10 years of GWAS discovery: Biology, function, and translation. American Journal of Human Genetics, 101(1), pp. 5-22.

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Truong, Steven, Saad, Nivene, Robinson, Philip, Cowderoy, Greg, Lim, Irwin, Schachna, Lionel, Stebbings, Simon, Stuckey, Stephen, Taylor, Andrew, Whittle, Samuel, Zochling, Jane, Bird, Paul, & Brown, Matt (2017) Consensus statements on the imaging of axial spondyloarthritis in Australia and New Zealand. Journal of Medical Imaging and Radiation Oncology, 61(1), pp. 58-69.

9

Zhou, Tiger, Souzeau, Emmanuelle, Siggs, Owen, Landers, John, Mills, Richard, Goldberg, Ivan, Healey, Paul, Graham, Stuart, Hewitt, Alex, Mackey, David, Galanopoulos, Anna, Casson, Robert, Ruddle, Jonathan, Ellis, Jonathan, Leo, Paul, Brown, Matthew, Macgregor, Stuart, Sharma, Shiwani, Burdon, Kathryn, & Craig, Jamie (2017) Contribution of mutations in known Mendelian glaucoma genes to advanced early-onset primary open-angle glaucoma. Investigative Ophthalmology and Visual Science, 58(3), pp. 1537-1544.

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Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jake, Garton, Fleur, Leo, Paul, Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Cremin, Katie, Harris, Jessica, Song, Sharon, Wheeler, Lawrie, Brown, Matt, & other, and (2017) Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8, Article number: 611 1-7.

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Bowes, John, Ashcroft, James, Dand, Nick, Jalalinajafabadi, Farideh, Bellou, Eftychia, Brown, Matt, & other, and (2017) Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis. Annals of the Rheumatic Diseases, 76(10), pp. 1774-1779.

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Leo, Paul, Madeleine, Margaret, Wang, Sophia, Schwartz, Stephen, Newell, Felicity, Brown, Matt, & other, and (2017) Defining the genetic susceptibility to cervical neoplasia - A genome-wide association study. PLoS Genetics, 13(8), Article number: e1006866 1-20.

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Roberts, Amity, Appleton, Louise, Cortes, Adrian, Vecellio, Matteo, Lau, Jonathan, Watts, Laura, Brown, Matt, & Wordsworth, Paul (B.P.) (2017) ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations. Proceedings of the National Academy of Sciences of the United States of America, 114(3), pp. 558-561.

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Tseng, Hsu-Wen, Glant, Tibor, Brown, Matt, Kenna, Tony, Thomas, Gethin, & Pettit, Allison (2017) Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis. BMC Musculoskeletal Disorders, 18, Article number: 228 1-9.

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Li, Zhixiu, Haynes, Katelin, Pennisi, David, Anderson, Lisa, Song, Xiaoxia, Thomas, Gethin, Kenna, Tony, Leo, Paul, & Brown, Matt (2017) Epigenetic and gene expression analysis of ankylosing spondylitis-associated loci implicate immune cells and the gut in the disease pathogenesis. Genes and Immunity, 18(3), pp. 135-143.

24

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Vlahovich, Nicole, Fricker, Peter, Brown, Matt, & Hughes, David (2017) Ethics of genetic testing and research in sport: A position statement from the Australian Institute of Sport. British Journal of Sports Medicine, 51, pp. 5-11.

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Jamalyaria, Farokh, Ward, Michael, Assassi, Shervin, Learch, Thomas, Lee, MinJae, Gensler, Lianne, Brown, Matt, Diekman, Laura, Tahanan, Amirali, Rahbar, Mohammad, Weisman, Michael, & Reveille, John (2017) Ethnicity and disease severity in ankylosing spondylitis a cross-sectional analysis of three ethnic groups. Clinical Rheumatology, 36(10), pp. 2359-2364.

48

Lau, Max, Keith, Patricia, Costello, Mary-Ellen, Bradbury, Linda, Hollis, Kelly, Thomas, Ranjeny, Thomas, Gethin, Brown, Matt, & Kenna, Tony (2017) Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis. Annals of the Rheumatic Diseases, 76(1), pp. 261-269.

36

Thomas, Gethin, Willner, Dana, Robinson, P., Cortes, Adrian, Duan, Ran, Rudwaleit, Martin, Akkoc, Nurullah, Braun, Jurgen, Chou, C., Maksymowych, Walter, Leo, Paul, Brown, Matt, & other, and (2017) Genetic diagnostic profiling in axial spondyloarthritis: a real world study. Clinical and Experimental Rheumatology, 35(2), pp. 229-233.

27

Hanson, Aimee & Brown, Matt (2017) Genetics and the causes of ankylosing spondylitis. Rheumatic Disease Clinics of North America, 43(3), pp. 401-414.

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Brown, Matt & Wordsworth, Paul (B.P.) (2017) Genetics in ankylosing spondylitis - Current state of the art and translation into clinical outcomes. Best Practice and Research in Clinical Haematology, 31(6), pp. 763-776.

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McInerney-Leo, Aideen, Wheeler, Lawrie, Marshall, Mhairi, Anderson, Lisa, Zankl, Andreas, Brown, Matt, Leo, Paul, Wicking, Carol, & Duncan, Emma (2017) Homozygous variant in C21orf2 in a case of Jeune syndrome with severe thoracic involvement: Extending the phenotypic spectrum. American Journal of Medical Genetics, Part A, 173(6), pp. 1698-1704.

19

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Bukhari, Wajih, Prain, Kerri, Waters, Patrick, Woodhall, Mark, O'Gorman, Cullen, Clarke, Laura, Silvestrini, Roger, Bundell, Christine, Abernethy, David, Bhuta, Sandeep, Brown, Matt, & other, and (2017) Incidence and prevalence of NMOSD in Australia and New Zealand. Journal of Neurology, Neurosurgery and Psychiatry, 88(8), pp. 632-638.

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Yin, Jian, He, Dongyi, Jiang, Lei, Cheng, Fang, Guo, Qian, Huang, Shaolan, Zeng, Xiaofeng, Liu, Yi, Brown, Matt, & Xu, Huji (2017) Influence of cigarette smoking on rheumatoid arthritis risk in the Han Chinese population. Frontiers in Medicine, 4, Article number: 76 1-7.

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Di Rocco, Maja, Bertamino, Marta, Brown, Matt, De Cunto, Carmen, Delai, Patricia, Eekhoff, Elisabeth, Haga, Nobuhiko, Hsiao, Edward, Keen, Richard, Morhart, Rolf, Pignolo, Robert, & Kaplan, Frederick (2017) International physician survey on management of FOP: A modified Delphi study. Orphanet Journal of Rare Diseases, 12(1), Article number: 110 1-5.

16

14

Shi, Hongjun, Enriquez, Annabelle, Rapadas, Melissa, Martin, Ella, Wang, Roni, McInerney-Leo, Aideen, Leo, Paul, Brown, Matt, Duncan, Emma, & other, and (2017) NAD deficiency, congenital malformations, and niacin supplementation. New England Journal of Medicine, 377(6), pp. 544-552.

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Brown, Matt & Bradbury, Linda (2017) New approaches in ankylosing spondylitis. Medical Journal of Australia, 206(5), pp. 192-194.

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Ranganathan, Vidya, Gracey, Eric, Brown, Matt, Inman, Robert, & Haroon, Nigel (2017) Pathogenesis of ankylosing spondylitis - recent advances and future directions. Nature Reviews Rheumatology, 13(6), pp. 359-367.

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Li, Zhixiu & Brown, Matthew A. (2017) Progress of genome-wide association studies of ankylosing spondylitis. Clinical and Translational Immunology, 6(12), Article number: e163.

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Lucas, Sionne, Zhou, Tiger, Blackburn, Nicholas, Mills, Richard, Ellis, Jonathan, Leo, Paul, Souzeau, Emmanuelle, Ridge, Bronwyn, Charlesworth, Jac, Brown, Matt, Lindsay, Richard, Craig, Jamie, & Burdon, Kathryn (2017) Rare, potentially pathogenic variants in ZNF469 are not enriched in keratoconus in a large Australian cohort of European descent. Investigative Ophthalmology and Visual Science, 58(14), pp. 6248-6256.

20

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Videm, Vibeke, Thomas, Ranjeny, Brown, Matt, & Hoff, Mari (2017) Self-reported diagnosis of rheumatoid arthritis or ankylosing spondylitis has low accuracy: Data from the Nord-Trondelag Health Study. Journal of Rheumatology, 44(8), pp. 1134-1141.

34

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Yang, Xinyu, Lin, Ke, Ni, Shanmin, Wang, Jianmin, Tian, Qingqing, Chen, Huaijun, Brown, Matt, Zheng, Kaidi, Zhai, Weitao, Sun, Li, Jin, Shengwei, & Wang, Jianguang (2017) Serum connective tissue growth factor is a highly discriminatory biomarker for the diagnosis of rheumatoid arthritis. Arthritis Research and Therapy, 19, Article number: 257 1-9.

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Wang, Xiaobing, Ellis, Jonathan, Pennisi, David, Song, Sharon, Batra, Jyotsna, Hollis, Kelly, Bradbury, Linda, Li, Zhixiu, Kenna, Tony, & Brown, Matt (2017) Transcriptome analysis of ankylosing spondylitis patients before and after TNF-a inhibitor therapy reveals the pathways affected. Genes and Immunity, 18, pp. 184-190.

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Zhou, Tiger, Souzeau, Emmanuelle, Sharma, Shiwani, Landers, John, Mills, Richard, Goldberg, Ivan, Healey, Paul, Graham, Stuart, Hewitt, Alex, Mackey, David, Galanopoulos, Anna, Casson, Robert, Ruddle, Jonathan, Ellis, Jonathan, Leo, Paul, Brown, Matthew, Macgregor, Stuart, Lynn, David, Burdon, Kathryn, & Craig, Jamie (2017) Whole exome sequencing implicates eye development, the unfolded protein response and plasma membrane homeostasis in primary open-angle glaucoma. PLoS One, 12(3), Article number: e0172427 1-18.

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Gratten, Jake, Zhao, Qiongyi, Benyamin, Beben, Garton, Fleur, He, Ji, Leo, Paul, Mangelsdorf, Marie, Anderson, Lisa, Zhang, Zong-Hong, Chen, Lu, Cremin, Katie, Harris, Jessica, Clout, Mhairi, Song, Sharon, Wheeler, Lawrie, Brown, Matt, & other, and (2017) Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese. Genome Medicine, 9, Article number: 97 1-9.

26

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Binder, Michele D., Fox, Andrew D., Merlo, Daniel, Johnson, Laura J., Giuffrida, Lauren, Calvert, Sarah E., Akkermann, Rainer, Ma, Gerry Z.M., Perera, Ashwyn A., Gresle, Melissa M., Laverick, Louise, Foo, Grace, Fabis-Pedrini, Marzena J., Spelman, Timothy, Jordan, Margaret A., Baxter, Alan G., Foote, Simon, Butzkueven, Helmut, Kilpatrick, Trevor J., Field, Judith, Kermode, Allan G., Taylor, Bruce, Booth, David R., Mason, Deborah, Stewart, Graeme J., Charlesworth, Jac, Wiley, James, Lechner-Scott, Jeannette, Tajouri, Lotti, Griffiths, Lyn, Slee, Mark, Brown, Matthew A., Moscato, Pablo, Scott, Rodney J., Broadley, Simon, Vucic, Steve, MCarroll, William, & other, and (2016) Common and Low Frequency Variants in MERTK Are Independently Associated with Multiple Sclerosis Susceptibility with Discordant Association Dependent upon HLA-DRB1*15:01 Status. PLoS Genetics, 12(3), Article number: e1005853.

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Ellinghaus, David, Jostins, Luke, Spain, Sarah, Cortes, Adrian, Bethune, Jorn, Brown, Matt, & other, and (2016) Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nature Genetics, 48(5), pp. 510-518.

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Okada, Yukinori, Suzuki, Akari, Ikari, Katsunori, Terao, Chikashi, Kochi, Yuta, Brown, Matthew, & other, and (2016) Contribution of a non-classical HLA gene, HLA-DOA, to the risk of rheumatoid arthritis. American Journal of Human Genetics, 99(2), pp. 366-374.

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Li, Zhixiu, Haynes, Katelin, Thomas, Gethin, Kenna, Tony, Leo, Paul, & Brown, Matt (2016) Epigenetic and expression analysis of Ankylosing spondylitis association loci point to key cell types driving disease (Conference Abstract). Arthritis and Rheumatology, 68(S10), p. 68.

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Robinson, Philip, Leo, Paul, Pointon, Jennifer, Harris, Jessica, Cremin, Katie, Bradbury, Linda, Stebbings, Simon, Harrison, Andrew, Duncan, Emma, Evans, David, Wordsworth, Paul (B.P.), Brown, Matt, & other, and (2016) Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease. npj Genomic Medicine, 1, Article number: 16008 1-6.

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McInerney-Leo, Aideen, Harris, Jessica, Gattas, Michael, Peach, Elizabeth, Sinnott, Stephen, Dudding-Byth, Tracy, Rajagopalan, Sulekha, Barnett, Christopher, Wheeler, Lawrie, Anderson, Lisa, Brown, Matt, Leo, Paul, Wicking, Carol, & Duncan, Emma (2016) Fryns syndrome associated with recessive mutations in PIGN in two separate families. Human Mutation, 37(7), pp. 695-702.

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Kenna, Tony, Hanson, Aimee, Costello, Mary-Ellen, & Brown, Matt (2016) Functional genomics and its bench-to-bedside translation pertaining to the identified susceptibility alleles and loci in ankylosing spondylitis. Current Rheumatology Reports, 18, Article number: 63 1-8.

6

Brown, Matthew, Kenna, Tony, & Wordsworth, Paul (B.P.) (2016) Genetics of ankylosing spondylitis - insights into pathogenesis. Nature Reviews Rheumatology, 12(2), pp. 81-91.

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Niu, Tianhua (Tim), Liu, Ning, Yu, Xun, Zhao, Ming, Choi, Hyung Jin, Leo, Paul, Brown, Matthew, Duncan, Emma, & other, and (2016) Identification of IDUA and WNT16 phosphorylation-related non-synonymous polymorphisms for bone mineral density in meta-analyses of genome-wide association studies. Journal of Bone and Mineral Research, 31(2), pp. 358-368.

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Tseng, Hsu-Wen, Pitt, Miranda, Glant, Tibor, McRae, Allan, Kenna, Tony, Brown, Matthew, Pettit, Allison, & Thomas, Gethin (2016) Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes. Arthritis Research and Therapy, 18, Article number: 35 1-12.

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Esapa, Christopher, Piret, Sian, Nesbit, M. Andrew, Loh, Nellie, Thomas, Gethin, Croucher, Peter, Brown, Matt, Brown, Steve, Cox, Roger, & Thakker, Rajesh (2016) Mice with an N-Ethyl-N-Nitrosourea (ENU) induced Tyr209Asn mutation in natriuretic peptide receptor 3 (NPR3) provide a model for kyphosis associated with activation of the MAPK signaling pathway. PLoS One, 11(12), Article number: e0167916 1-18.

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McInerney-Leo, Aideen, Le Goff, Carine, Leo, Paul, Kenna, Tony, Keith, Patricia, Harris, Jessica, Steer, Ruth, Bole-Feysot, Christine, Nitschke, Patrick, Kielty, Cay, Brown, Matt, Zankl, Andreas, Duncan, Emma, & Cormier-Daire, Valerie (2016) Mutations in LTBP3 cause acromicric dysplasia and geleophysic dysplasia. Journal of Medical Genetics, 53(7), pp. 457-464.

51

53

Wade, Emma, Daniel, Philip, Jenkins, Zandra, McInerney-Leo, Aideen, Leo, Paul, Morgan, Tim, Addor, Marie-Claude, Ades, Lesley, Bertola, Debora, Bohring, Axel, other, and, Brown, Matt, & Duncan, Emma (2016) Mutations in MAP3K7 that alter the activity of the TAK1 signaling complex cause frontometaphyseal dysplasia. American Journal of Human Genetics, 99(2), pp. 392-406.

63

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Cortes, Claudio, McInerney-Leo, Aideen, Vogel, Ida, Rondon Galeano, Maria, Leo, Paul, Harris, Jessica, Anderson, Lisa, Keith, Patricia, Brown, Matt, Ramsing, Mette, Duncan, Emma, Zankl, Andreas, & Wicking, Carol (2016) Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 function. Scientific Reports, 6, Article number: 24083 1-10.

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26

Gregson, Celia, Wheeler, Lawrie, Hardcastle, Sarah, Appleton, Louise, Addison, Kathryn, Brugmans, Marieke, Clark, Graeme, Ward, Kate, Paggiosi, Margaret, Stone, Mike, Brown, Matthew, Duncan, Emma, & other, and (2016) Mutations in known monogenic high bone mass loci only explain a small proportion of high bone mass cases. Journal of Bone and Mineral Research, 31(3), pp. 640-649.

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Lester, Susan, Hewitt, Alex, Ruediger, Carlee, Bradbury, Linda, De Smit, Elisabeth, Wiese, Michael, Black, Rachel, Harrison, Andrew, Jones, Graeme, Littlejohn, Geoffrey, Merriman, Tony, Shenstone, Bain, Smith, Malcolm, Rischmueller, Maureen, Brown, Matt, & Hill, Catherine (2016) PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis. RMD Open, 2(1), Article number: e000246 1-4.

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Rautanen, Anna, Pirinen, Matti, Mills, Tara, Rockett, Kirk, Strange, Amy, Ndungu, Anne, Naranbhai, Vivek, Gilchrist, James, Bellenguez, Celine, Freeman, Colin, other, and, & Brown, Matt (2016) Polymorphism in a lincRNA associates with a doubled risk of pneumococcal bacteremia in Kenyan children. American Journal of Human Genetics, 98(6), pp. 1092-1100.

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Li, Zhixiu, Akar, Servet, Yarkan, Handan, Cetin, Pinar, Can, Gerçek, Harris, Jessica, Brown, Matt, & other, and (2016) Rare Mediterranean Fever (MEFV) gene polymorphisms are associated with Ankylosing spondylitis in Turkish and Iranian population (Conference Abstract). Arthritis and Rheumatology, 68(S10), p. 3123.

163

Zhou, Tiger, Souzeau, Emmanuelle, Sharma, Shiwani, Siggs, Owen, Goldberg, Ivan, Healey, Paul, Graham, Stuart, Hewitt, Alex, Mackey, David, Casson, Robert, Landers, John, Mills, Richard, Ellis, Jonathan, Leo, Paul, Brown, Matthew, Macgregor, Stuart, Burdon, Kathryn, & Craig, Jamie (2016) Rare variants in optic disc area gene CARD10 enriched in primary open-angle glaucoma. Molecular Genetics and Genomic Medicine, 4(6), pp. 624-633.

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Robinson, Philip, Leo, Paul, Pointon, Jennifer, Harris, Jessica, Cremin, Katie, Bradbury, Linda, Stebbings, Simon, Harrison, Andrew, Evans, D., Duncan, Emma, Wordsworth, Paul (B.P.), Brown, Matthew, & other, and (2016) The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis. Genes and Immunity, 17(1), pp. 46-51.

34

31

Bodea, Corneliu, Neale, Benjamin, Ripke, Stephan, Daly, Mark, Devlin, Bernie, Roeder, Kathryn, Brown, Matt, & other, and (2016) A method to exploit the structure of genetic ancestry space to enhance case-control studies. American Journal of Human Genetics, 98(5), pp. 857-868.

13

van der Linden, Sjef, Akkoc, Nurullah, Brown, Matthew, Robinson, Philip, & Khan, Muhammad (2015) The ASAS criteria for axial Spondyloarthritis: Strengths, weaknesses, and proposals for a way forward. Current Rheumatology Reports, 17(9), Article number: 62 1-12.

40

43

He, Ji, Mangelsdorf, Marie, Fan, Dongsheng, Bartlett, Perry, & Brown, Matthew (2015) Amyotrophic lateral sclerosis genetic studies: From genome-wide association mapping to genome sequencing. The Neuroscientist, 21(6), pp. 599-615.

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Cortes, Adrian, Maksymowych, Walter, Wordsworth, Paul (B.P.), Inman, R., Danoy, Patrick, Rahman, P., Stone, M., Corr, M., Gensler, Lianne, Brown, Matthew, & other, and (2015) Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis. Annals of the Rheumatic Diseases, 74(7), pp. 1387-1393.

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He, Ji, Tang, Lu, Benyamin, Beben, Shah, Sonia, Hemani, Gibran, Liu, Rong, Ye, Shan, Liu, Xiaolu, Ma, Yan, Zhang, Huagang, Cremin, Katie, Leo, Paul, Wray, Naomi, Visscher, Peter, Xu, Huji, Brown, Matthew, Bartlett, Perry, Mangelsdorf, Marie, & Fan, Dongsheng (2015) C9orf72 hexanucleotide repeat expansions in Chinese sporadic amyotrophic lateral sclerosis. Neurobiology of Aging, 36(9), 2660.e1-2660.e8.

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McInerney-Leo, Aideen, Duncan, Emma, Leo, Paul, Gardiner, Brooke, Bradbury, Linda, Harris, Jessica, Clark, Graeme, Brown, Matthew, & Zankl, Andreas (2015) COL1A1 C-propeptide cleavage site mutation causes high bone mass, bone fragility and jaw lesions: a new cause of gnathodiaphyseal dysplasia? Clinical Genetics, 88(1), pp. 49-55.

16

14

Freitag, Daniel, Butterworth, Adam, Willeit, Peter, Howson, Joanna, Burgess, Stephen, Kaptoge, Stephen, Young, Robin, Kee Ho, Weang, Wood, Angela, Brown, Matthew, & other, and (2015) Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis. The Lancet Diabetes and Endocrinology, 3(4), pp. 243-253.

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McInerney-Leo, Aideen, Sparrow, Duncan, Harris, Jessica, Gardiner, Brooke, Marshall, Mhairi, O'Reilly, Victoria, Shi, Hongjun, Brown, Matthew, Leo, Paul, Zankl, Andreas, Dunwoodie, Sally, & Duncan, Emma (2015) Compound heterozygous mutations in RIPPLY2 associated with vertebral segmentation defects. Human Molecular Genetics, 24(5), pp. 1234-1242.

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Bowes, John, Budu-Aggrey, Ashley, Huffmeier, Ulrike, Uebe, Steffen, Steel, Kathryn, Brown, Matthew, & other, and (2015) Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis. Nature Communications, 6, Article number: 6046 1-10.

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Kenna, Tony, Lau, Max, Keith, Patricia, Ciccia, Francesco, Costello, Mary-Ellen, Bradbury, Linda, Low, P-L., Agrawal, Nitish, Triolo, Giovanni, Alessandro, R., Robinson, Philip, Thomas, Gethin, & Brown, Matthew (2015) Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis. Genes and Immunity, 16(1), pp. 35-42.

30

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Robinson, Philip, Lau, Eugene, Keith, Patricia, Lau, Max, Thomas, Gethin, Bradbury, Linda, Brown, Matthew, & Kenna, Tony (2015) ERAP2 functional knockout in humans does not alter surface heavy chains or HLA-B27, inflammatory cytokines or endoplasmic reticulum stress markers. Annals of the Rheumatic Diseases, 74(11), pp. 2092-2095.

18

Robinson, Philip, Costello, Mary-Ellen, Leo, Paul, Bradbury, Linda, Hollis, Kelly, Cortes, Adrian, Lee, Seunghun, Joo, Kyung Bin, Shim, Seung-Cheol, Brown, Matthew, & other, and (2015) ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients [Letter]. Annals of the Rheumatic Diseases, 74(8), pp. 1627-1629.

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van de Bunt, Martijn, Cortes, Adrian, Brown, Matthew, Morris, Andrew, & McCarthy, Mark (2015) Evaluating the performance of fine-mapping strategies at common variant GWAS loci. PLoS Genetics, 11(9), Article number: e1005535 1-14.

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Robinson, Philip, Claushuis, Theodora, Cortes, Adrian, Martin, Tammy, Evans, David, Leo, Paul, Mukhopadhyay, Pamela, Bradbury, Linda, Cremin, Katie, Harris, Jessica, Brown, Matthew, & other, and (2015) Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis. Arthritis and Rheumatology, 67(1), pp. 140-151.

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Reppe, Sjur, Wang, Yunpeng, Thompson, Wesley, McEvoy, Linda, Zuber, Verena, LeBlanc, Marissa, Bettella, Francesco, Mills, Ian, Desikan, Rahul, Djurovic, Srdjan, Gautvik, Kaare, Dale, Anders, Andreassen, Ole, Brown, Matthew, & other, and (2015) Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci. PLoS One, 10(12), Article number: e0144531 1-20.

176

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Burdon, Kathryn, Fogarty, Rhys, Shen, Weiyong, Abhary, Sotoodeh, Kaidonis, Georgia, Appukuttan, Binoy, Hewitt, Alex, Sharma, Shiwani, Daniell, Mark, Brown, Matthew, & other, and (2015) Genome-wide association study for sight-threatening diabetic retinopathy reveals association with genetic variation near the GRB2 gene. Diabetologia, 58(10), pp. 2288-2297.

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Niu, Tianhua (Tim), Liu, Ning, Zhao, Ming, Xie, Guie, Zhang, Lei, Li, Jian, Pei, Yu-Fang, Shen, Hui, Fu, Xiaoying, He, Hao, Leo, Paul, Duncan, Emma, Brown, Matthew, & other, and (2015) Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies. Human Molecular Genetics, 24(16), pp. 4710-4727.

21

Costello, Mary-Ellen, Ciccia, Francesco, Willner, Dana, Warrington, Nicole, Robinson, Philip, Gardiner, Brooke, Marshall, Mhairi, Kenna, Tony, Triolo, Giovanni, & Brown, Matthew (2015) Intestinal dysbiosis in ankylosing spondylitis. Arthritis and Rheumatology, 67(3), pp. 686-691.

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Field, Judith, Shahijanian, Fernando, Schibeci, Stephen, Johnson, Laura, Gresle, Melissa, Laverick, Louise, Parnell, Grant, Stewart, Graeme, McKay, Fiona, Kilpatrick, Trevor, Butzkueven, Helmut, Booth, David, Brown, Matthew, & other, and (2015) The MS risk allele of CD40 is associated with reduced cell-membrane bound expression in antigen presenting cells: Implications for gene function. PLoS One, 10(6), Article number: e0127080 1-14.

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Cortes, Adrian, Pulit, Sara, Leo, Paul, Pointon, Jennifer, Robinson, Philip, Weisman, Michael, Ward, Michael, Gensler, Lianne, Zhou, Xiaodong, Brown, Matthew, & other, and (2015) Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1. Nature Communications, 6, Article number: 7146 1-8.

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Esapa, Christopher, Hannan, Fadil, Babinsky, Valerie, Potter, Paul, Thomas, Gethin, Croucher, Peter, Brown, Matthew, Brown, Steve, Cox, Roger, & Thakker, Rajesh (2015) N-ethyl-N-nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models. PLoS One, 10(4), Article number: e0122650 1-19.

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Bowes, John, Loehr, Sabine, Budu-Aggrey, Ashley, Uebe, Steffen, Bruce, Ian, Feletar, Marie, Marzo-Ortega, Helena, Helliwell, Phillip, Ryan, Anthony, Kane, David, Brown, Matthew, & other, and (2015) PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus. Annals of the Rheumatic Diseases, 74(10), pp. 1882-1885.

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Haynes, Katelin, Tseng, Hsu-Wen, Kneissel, Michaela, Glant, Tibor, Brown, Matthew, & Thomas, Gethin (2015) Treatment of a mouse model of ankylosing spondylitis with exogenous sclerostin has no effect on disease progression. BMC Musculoskeletal Disorders, 16, Article number: 368 1-8.

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11

Cuellar-Partida, Gabriel, Springelkamp, Henriet, Lucas, Sionne, Yazar, Seyhan, Hewitt, Alex, Iglesias, Adriana, Montgomery, Grant, Martin, Nicholas, Pennell, Craig, van Leeuwen, Elisabeth, Verhoeven, Virginie, Hofman, Albert, Uitterlinden, Andre, Ramdas, Wishal, Wolfs, Roger, Vingerling, Johannes, Brown, Matthew, Mills, Richard, Craig, Jamie, Klaver, Caroline, van Duijn, Cornelia, Burdon, Kathryn, Macgregor, Stuart, & Mackey, David (2015) WNT10A exonic variant increases the risk of keratoconus by decreasing corneal thickness. Human Molecular Genetics, 24(17), pp. 5060-5068.

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McInerney-Leo, Aideen, Harris, Jessica, Leo, Paul, Marshall, Mhairi, Gardiner, Brooke, Kinning, E., Leong, Huey Yin, McKenzie, Fiona, Ong, W., Vodopiutz, Julia, Wicking, Carol, Brown, Matthew, Zankl, Andreas, & Duncan, Emma (2015) Whole exome sequencing is an efficient, sensitive and specific method for determining the genetic cause of short-rib thoracic dystrophies. Clinical Genetics, 88(6), pp. 550-557.

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Aung, Tin, Ozaki, Mineo, Mizoguchi, Takanori, Allingham, R. Rand, Li, Zheng, Leo, Paul, Brown, Matthew, & other, and (2015) A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. Nature Genetics, 47(4), pp. 387-392.

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Costello, Mary-Ellen, Robinson, Philip, Benham, Helen, & Brown, Matthew (2015) The intestinal microbiome in human disease and how it relates to arthritis and spondyloarthritis. Best Practice and Research in Clinical Rheumatology, 29(2), pp. 202-212.

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Zankl, Andreas, Duncan, Emma L., Leo, Paul J., Clark, Graeme R., Glazov, Evgeny A., Addor, Marie-Claud, Herlin, Troels, Kim, Chong Ae, Leheup, Bruno P., McGill, Jim, McTaggart, Steven, Mittas, Stephen, Mitchell, Anna L., Mortier, Geert R., Robertson, Stephen P., Schroeder, Marie, Terhal, Paulien, & Brown, Matthew A. (2014) Erratum: Multicentric carpotarsal osteolysis is caused by mutations clustering in the amino-terminal transcriptional activation domain of MAFB. American Journal of Human Genetics, 94(4), p. 643.

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Karaderi, Tugce, Keidel, S., Pointon, J., Appleton, L., Brown, Matthew, Evans, D., & Wordsworth, Paul (B.P.) (2014) Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene (ANTXR2). Annals of the Rheumatic Diseases, 73(11), pp. 2054-2058.

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Pahau, Helen, Brown, Matthew, Paul, Sanjoy, Thomas, Ranjeny, & Videm, Vibeke (2014) Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: The population-based Nord-Trondelag health study (HUNT). Arthritis Research and Therapy, 16(2), Article number: R85 1-9.

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Gharahkhan, Puya, Burdon, Kathryn, Fogarty, Rhys, Sharma, Shiwani, Hewitt, Alex, Martin, Sarah, Law, Matthew, Cremin, Katie, Cooke Bailey, Jessica, Loomis, Stephanie, Brown, Matthew, & other, and (2014) Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma. Nature Genetics, 46(10), pp. 1120-1125.

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Robinson, Philip, Bird, Paul, Lim, Irwin, Saad, Nivene, Schachna, Lionel, Taylor, Andrew, Whittle, Samuel, & Brown, Matthew (2014) Consensus statement on the investigation and management of non-radiographic axial spondyloarthritis (nr-axSpA). International Journal of Rheumatic Diseases, 17(5), pp. 548-556.

12

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Videm, Vibeke, Cortes, Adrian, Thomas, Ranjeny, & Brown, Matthew (2014) Current smoking is associated with incident ankylosing spondylitis - The HUNT population-based Norwegian health study. Journal of Rheumatology, 41(10), pp. 2041-2048.

66

Rosenbaum, James, Lin, Phoebe, Asquith, Mark, Costello, Mary-Ellen, Kenna, Tony, & Brown, Matthew (2014) Does the microbiome play a causal role in spondyloarthritis? Clinical Rheumatology, 33(6), pp. 763-767.

25

20

Bruges-Armas, Jacome, Bettencourt, Bruno, Couto, Ana, Lima, Manuela, Rodrigues, Ana, Vastesaeger, Nathan, & Brown, Matthew (2014) Effectiveness and safety of infliximab in two cases of severe chondrocalcinosis: Nine years of follow-up. Case Reports in Rheumatology, 2014, Article number: 536856 1-5.

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Jiang, L., Yin, J., Ye, L., Yang, J., Hemani, G., Liu, A. J., Zou, H., He, D., Sun, L., Zeng, X., Li, Z., Zheng, Y., Lin, Y., Liu, Y., Fang, Y., Xu, J., Li, Y., Dai, S., Guan, J., Wei, Q., Wang, Y., Huang, C., Zuo, X., Wu, X., Zhang, L., Zhou, L., Zhang, Q., Li, T., Chen, L., Xu, Z., Yang, X., Qian, F., Xie, W., Liu, W., Guo, Q., Huang, S., Zhao, J., Li, M., Jin, Y., Gao, J., Lv, Y., Lin, L., Guo, A., Danoy, P., Willner, D., Cremin, C., Hadler, J., Zhang, F., Zhao, Y., Yue, T., Fan, X., Guo, J., Mu, R., Li, J., Wu, C., Zeng, M., Wang, J., Li, S., Jin, L., Wang, B., Ma, X., Zhang, X., Brown, Matthew A., Visscher, P. M., Su, D. F., & Xu, H. (2014) Erratum: Incorrect institutional affiliations of authors in the article by Jiang et al (Arthritis Rheumatol (2014). Arthritis and Rheumatology, 66(7), p. 1881.

1

Ivanov, Ivan, Azmanov, Dimitar, Ivanova, Mariya, Chamova, Teodora, Pacheva, Ilyana, Panova, Margarita, Song, Sharon, Morar, Bharti, Yordanova, Ralitsa, Brown, Matthew, & other, and (2014) Founder p.Arg 446* mutation in the PDHX gene explains over half of cases with congenital lactic acidosis in Roma children. Molecular Genetics and Metabolism, 113(1 - 2), pp. 76-83.

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Agrawal, Nitish & Brown, Matthew (2014) Genetic associations and functional characterization of M1 aminopeptidases and immune-mediated diseases. Genes and Immunity, 15(8), pp. 521-527.

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Moayyeri, Alireza, Hsu, Yi-Hsiang, Karasik, David, Estrada, Karol, Xiao, Su-Mei, Nielson, Carrie, Srikanth, Priya, Giroux, Sylvie, Wilson, Scott, Brown, Matthew, & other, and (2014) Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Human Molecular Genetics, 23(11), pp. 3054-3068.

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Robinson, Philip & Brown, Matthew (2014) Genetics of ankylosing spondylitis. Molecular Immunology, 57(1), pp. 2-11.

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Okada, Yukinori, Wu, Di, Trynka, Gosia, Raj, Towfique, Terao, Chikashi, Ikari, Katsunori, Kochi, Yuta, Ohmura, Koichiro, Suzuki, Akari, Yoshida, Shinji, Brown, Matthew, & other, and (2014) Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature, 506(7488), pp. 376-381.

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Ferreira, Manuel, Matheson, Melanie, Tang, Clara, Granell, Raquel, Ang, Wei, Hui, Jennie, Kiefer, Amy, Duffy, David, Baltic, Svetlana, Brown, Matthew, & other, and (2014) Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. Journal of Allergy and Clinical Immunology, 133(6), pp. 1564-1571.

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Oei, Ling, Estrada, Karol, Duncan, Emma, Christiansen, Claus, Liu, Ching-Ti, Langdahl, Bente, Obermayer-Pietsch, Barbara, Riancho, Jose, Prince, Richard, Brown, Matthew, & other, and (2014) Genome-wide association study for radiographic vertebral fractures: A potential role for the 16q24 BMD locus. Bone, 59, pp. 20-27.

29

26

Lazarus, Syndia, McInerney-Leo, Aideen, McKenzie, Fiona, Baynam, Gareth, Broley, Stephanie, Cavan, Barbra, Munns, Craig, Pruijs, Johannes Egbertus Hans, Sillence, David, Terhal, Paulien, Pryce, Karena, Brown, Matthew, Zankl, Andreas, Thomas, Gethin, & Duncan, Emma (2014) The IFITM5 mutation c.-14C>T results in an elongated transcript expressed in human bone; and causes varying phenotypic severity of osteogenesis imperfecta type V. BMC Musculoskeletal Disorders, 15, Article number: 107 1-6.

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Mayes, Maureen, Bossini-Castillo, Lara, Gorlova, Olga, Martin, Jose Ezequiel, Zhou, Xiaodong, Chen, Wei, Assassi, Shervin, Ying, Jun, Brown, Matthew, & other, and (2014) Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. American Journal of Human Genetics, 94(1), pp. 47-61.

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Zochling, Jane, Newell, Felicity, Charlesworth, Jac, Leo, Paul, Stankovich, Jim, Cortes, Adrian, Zhou, Yuan, Stevens, Wendy, Sahhar, Joanne, Roddy, Janet, Nash, Peter, Tymms, Kathleen, Rischmueller, Maureen, Lester, Susan, Proudman, Susanna, & Brown, Matthew (2014) An Immunochip-based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3. Arthritis Research and Therapy, 16, Article number: 438 1-7.

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Benham, Helen, Rehaume, Linda, Hasnain, Sumaira, Velasco, Jared, Baillet, Athan, Ruutu, Merja, Kikly, Kristine, Wang, Ran, Tseng, Hsu-Wen, Thomas, Gethin, Brown, Matthew, Strutton, Geoffrey, McGuckin, Michael, & Thomas, Ranjeny (2014) Interleukin-23 mediates the intestinal response to microbial Beta-1,3-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis and Rheumatology, 66(7), pp. 1755-1767.

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Bentley, Liz, Esapa, Christopher, Nesbit, M. Andrew, Head, Rosie, Evans, Holly, Lath, Darren, Scudamore, Cheryl, Hough, Tertius, Podrini, Christine, Hannan, Fadil, Fraser, William, Croucher, Peter, Brown, Matthew, Brown, Steve, Cox, Roger, & Thakker, Rajesh (2014) An N-ethyl-n-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess. Endocrinology, 155(3), pp. 908-922.

31

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Jiang, Lei, Yin, Jian, Ye, Lingying, Yang, Jian, Hemani, Gibran, Liu, Ai-jun, Zou, Hejian, He, Dongyi, Sun, Lingyun, Brown, Matthew, & other, and (2014) Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans. Arthritis and Rheumatology, 66(5), pp. 1121-1132.

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Postmus, Iris, Trompet, Stella, Deshmukh, Harshal, Barnes, Michael, Li, Xiaohui, Brown, Matthew, & other, and (2014) Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nature Communications, 5, Article number: 5068 1-10.

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Okada, Yukinori, Kim, Kwangwoo, Han, Buhm, Pillai, Nisha, Ong, Rick Twee-Hee, Saw, Woei-Yuh, Luo, Ma, Jiang, Lei, Yin, Jian, Bang, So-Young, Lee, Hye-Soon, Brown, Matthew, Bae, Sang-Cheol, Xu, Huji, Teo, Yik-Ying, de Bakker, Paul, & Raychaudhuri, Soumya (2014) Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations. Human Molecular Genetics, 23(25), pp. 6916-6926.

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McWhirter, Rebekah, Thomson, Russell, Marthick, James, Rumbold, Alice, Brown, Matthew, Taylor-Thomson, Debbie, Maypilama, Elaine, Condon, John, & Dickinson, Joanne (2014) Runs of homozygosity and a cluster of vulvar cancer in young Australian Aboriginal women. Gynecologic Oncology, 133(3), pp. 421-426.

18

16

van der Heijde, Desiree, Sieper, Joachim, Maksymowych, Walter, Brown, Matthew, Lambert, Robert, Rathmann, Suchitrita, & Pangan, Aileen (2014) Spinal inflammation in the absence of sacroiliac joint inflammation on magnetic resonance imaging in patients with active nonradiographic axial spondyloarthritis. Arthritis and Rheumatology, 66(3), pp. 667-673.

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Cremin, Katie, Leo, Paul, Harris, Jessica, De Smit, Elisabeth, Bradbury, Linda, McKelvie, Penny, Hill, Catherine, Brown, Matthew, & Hewitt, Alex (2014) Utility of temporal artery biopsy samples for genome-wide analysis of giant cell arteritis. Genes and Immunity, 15(5), pp. 338-340.

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McInerney-Leo, Aideen, Marshall, Mhairi, Gardiner, Brooke, Benn, Diana, McFarlane, Janelle, Robinson, Bruce, Brown, Matthew, Leo, Paul, Clifton-Bligh, Roderick, & Duncan, Emma (2014) Whole exome sequencing is an efficient and sensitive method for detection of germline mutations in patients with phaeochromcytomas and paragangliomas. Clinical Endocrinology, 80(1), pp. 25-33.

34

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van Dongen, Jenny, Jansen, Rick, Smit, Dirk, Hottenga, Jouke-Jan, Mbarek, Hamdi, Willemsen, Gonneke, Kluft, Cornelis, Penninx, Brenda, Ferreira, Manuel, Boomsma, Dorret, de Geus, Eco, Nyholt, Dale, Brown, Matthew, & other, and (2014) The contribution of the functional IL6R polymorphism rs2228145, eQTLs and other genome-wide SNPs to the heritability of plasma sIL-6R levels. Behavior Genetics, 44(4), pp. 368-382.

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Davis, Oliver, Band, Gavin, Pirinen, Matti, Haworth, Claire, Meaburn, Emma, Kovas, Yulia, Harlaar, Nicole, Docherty, Sophia, Hanscombe, Ken, Brown, Matthew, & other, and (2014) The correlation between reading and mathematics ability at age twelve has a substantial genetic component. Nature Communications, 5, Article number: 4204 1-6.

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Duncan, Emma, Brown, Matthew, & Shore, Eileen (2014) The revolution in human monogenic disease mapping. Genes, 5(3), pp. 792-803.

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Robinson, Philip & Brown, Matthew (2014) The window of opportunity: a relevant concept for axial spondyloarthritis. Arthritis Research and Therapy, 16(3), Article number: 109 1-3.

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Sparrow, Duncan, McInerney-Leo, Aideen, Gucev, Zoran, Gardiner, Brooke, Marshall, Mhairi, Leo, Paul, Chapman, Deborah, Tasic, Velibor, Shishko, Abduhadi, Brown, Matthew, Duncan, Emma, & Dunwoodie, Sally (2013) Autosomal dominant spondylocostal dysostosis is caused by mutation in TBX6. Human Molecular Genetics, 22(8), pp. 1625-1631.

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Robinson, Philip, Wordsworth, Paul (B.P.), Reveille, John, & Brown, Matthew (2013) Axial spondyloarthritis: a new disease entity, not necessarily early ankylosing spondylitis [Viewpoint]. Annals of the Rheumatic Diseases, 72(2), pp. 162-164.

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Mechelli, Rosella, Umeton, Renato, Policano, Claudia, Annibali, Viviana, Coarelli, Giulia, Ricigliano, Vito, Vittori, Danila, Fornasiero, Arianna, Buscarinu, Maria Chiara, Brown, Matthew, & other, and (2013) A 'Candidate-Interactome' aggregate analysis of genome-wide association data in multiple sclerosis. PLoS One, 8(5), Article number: e63300 1-9.

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Fakiola, Michaela, Strange, Amy, Cordell, Heather, Miller, E. Nancy, Pirinen, Matti, Su, Zhan, Mishra, Anshuman, Mehrotra, Sanjana, Monteiro, Gloria, Brown, Matthew, & other, and (2013) Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nature Genetics, 45(2), pp. 208-213.

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Jiang, Lei, Willner, Dana, Danoy, Patrick, Xu, Huji, & Brown, Matthew (2013) Comparison of the performance of two commercial genome-wide association study genotyping platforms in Han Chinese samples. G3: Genes, Genomes, Genetics, 3(1), pp. 23-29.

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Halbritter, Jan, Bizet, Albane, Schmidts, Miriam, Porath, Jonathan, Braun, Daniela, Gee, Heon Yung, McInerney-Leo, Aideen, Krug, Pauline, Filhol, Emilie, Brown, Matthew, Duncan, Emma, & other, and (2013) Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans. American Journal of Human Genetics, 93(5), pp. 915-925.

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Sieper, Joachim, van der Heijde, Desiree, Dougados, Maxime, Mease, Philip, Maksymowych, Walter, Brown, Matthew, Arora, Vipin, & Pangan, Aileen (2013) Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: Results of a randomised placebo-controlled trial (ABILITY-1). Annals of the Rheumatic Diseases, 72(6), pp. 815-822.

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38

Davidson, S. I., Jiang, L., Cortes, A., Wu, X., Glazov, E. A., Zheng, Y., Danoy, P. A., Liu, Y., Thomas, G. P., Brown, Matthew A., Xu, H., & Donskoi, M. (2013) Erratum: Omission of author name in the article by Davidson et al (Arthritis Rheum, July 2013). Arthritis and Rheumatism, 65(9), p. 2496.

Thomas, Gethin, Duan, Ran, Pettit, Allison, Weedon, Helen, Kaur, Simranpreet, Smith, Malcolm, & Brown, Matthew (2013) Expression profiling in spondyloarthropathy synovial biopsies highlights changes in expression of inflammatory genes in conjunction with tissue remodelling genes. BMC Musculoskeletal Disorders, 14, Article number: 354 1-9.

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Parkes, Miles, Cortes, Adrian, van Heel, David, & Brown, Matthew (2013) Genetic insights into common pathways and complex relationships among immune-mediated diseases. Nature Reviews Genetics, 14(9), pp. 661-673.

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Ripke, Stephan, O'Dushlaine, Colm, Chambert, Kimberly, Moran, Jennifer, Kahler, Anna, Akterin, Susanne, Bergen, Sarah, Collins, Ann, Crowley, James, Brown, Matthew, & other, and (2013) Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nature Genetics, 45(10), pp. 1150-1159.

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2

Strange, Amy, Bellenguez, Celine, Sim, Xueling, Luben, Robert, Hysi, Pirro, Ramdas, Wishal, Koolwijk, Leonieke, Freeman, Colin, Pirinen, Matti, Brown, Matthew, & other, and (2013) Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. Human Molecular Genetics, 22(22), pp. 4653-4660.

30

Chia, N., Bryce, M., Hickman, Peter, Potter, Julia, Glasgow, Nicholas, Koerbin, Gus, Danoy, Patrick, Brown, Matthew, & Cavanaugh, Juleen (2013) High-resolution SNP microarray investigation of copy number variations on chromosome 18 in a control cohort. Cytogenetic and Genome Research, 141(1), pp. 16-25.

Davidson, Stuart, Jiang, Lei, Cortes, Adrian, Wu, Xin, Glazov, Evgeny, Zheng, Yi, Danoy, Patrick, Liu, Yi, Thomas, Gethin, Brown, Matthew, & Xu, Huji (2013) High-throughput sequencing of IL23R reveals a low-frequency, nonsynonymous single-nucleotide polymorphism that is associated with ankylosing spondylitis in a Han Chinese population. Arthritis and Rheumatism, 65(7), pp. 1747-1752.

29

28

Cortes, Adrian, Hadler, Johanna, Pointon, Jennifer, Robinson, Philip, Karaderi, Tugce, Leo, Paul, Cremin, Katie, Pryce, Karena, Harris, Jessica, Brown, Matthew, & other, and (2013) Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nature Genetics, 45(7), pp. 730-738.

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Lin, Rui, Charlesworth, Jac, Stankovich, Jim, Perreau, Victoria, Brown, Matthew, Taylor, Bruce, & other, and (2013) Identity-by-descent mapping to detect rare variants conferring susceptibility to multiple sclerosis. PLoS One, 8(3), Article number: e56379 1-8.

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Kenna, Tony & Brown, Matthew (2013) Immunopathogenesis of ankylosing spondylitis. International Journal of Clinical Rheumatology, 8(2), pp. 265-274.

20

Zheng, Hou-Feng, Duncan, Emma, Yerges-Armstrong, Laura, Eriksson, Joel, Bergstrom, Ulrica, Leo, Paul, Leslie, William, Goltzman, David, Blangero, John, Brown, Matthew, & other, and (2013) Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm. Journal of Medical Genetics, 50(7), pp. 473-478.

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Costello, Mary-Ellen, Elewaut, Dirk, Kenna, Tony, & Brown, Matthew (2013) Microbes, the gut and ankylosing spondylitis. Arthritis Research and Therapy, 15, Article number: 214 1-10.

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Ruark, Elise, Snape, Katie, Humburg, Peter, Loveday, Chey, Bajrami, Ilirjana, Brough, Rachel, Rodrigues, Daniel Nava, Renwick, Anthony, Seal, Sheila, Brown, Matthew, & other, and (2013) Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer. Nature, 493(7432), pp. 406-410.

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Schmidts, Miriam, Vodopiutz, Julia, Christou-Savina, Sonia, Cortes, Claudio, McInerney-Leo, Aideen, Emes, Richard, Arts, Heleen, Tuysuz, Beyhan, D'Silva, Jason, Brown, Matthew, & other, and (2013) Mutations in the gene encoding IFT Dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophy. American Journal of Human Genetics, 93(5), pp. 932-944.

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Cortes, Adrian, Field, Judith, Glazov, Evgeny, Hadler, Johanna, Stankovich, Jim, Brown, Matthew, Baxter, Alan, Kermode, Allan, Taylor, Bruce, Booth, David, Mason, Deborah, Stewart, Graeme, Butzkueven, Helmut, Charlesworth, Jac, Wiley, James, Lechner-Scott, Jeannette, Tajouri, Lotti, Griffiths, Lyn, & other, and (2013) Resequencing and fine-mapping of the chromosome 12q13-14 locus associated with multiple sclerosis refines the number of implicated genes. Human Molecular Genetics, 22(11), pp. 2283-2292.

18

14

van Scheltinga, A. F. Terwisscha, Bakker, S., van Haren, Neeltje, Derks, E., Buizer-Voskamp, Jacobine, Cahn, Wiepke, Ripke, Stephan, Ophoff, Roel, Kahn, Rene, Brown, Matthew, & other, and (2013) Schizophrenia genetic variants are not associated with intelligence. Psychological Medicine, 43(12), pp. 2563-2570.

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McInerney-Leo, Aideen, Schmidts, Miriam, Cortes, Claudio, Leo, Paul, Gener, Blanca, Courtney, Andrew, Gardiner, Brooke, Harris, Jessica, Lu, Yeping, Marshall, Mhairi, Scambler, Peter, Beales, Philip, Brown, Matthew, Zankl, Andreas, Mitchison, Hannah, Duncan, Emma, & Wicking, Carol (2013) Short-rib polydactyly and Jeune syndromes are caused by mutations in WDR60. American Journal of Human Genetics, 93(3), pp. 515-523.

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McInerney-Leo, Aideen, Marshall, Mhairi, Gardiner, Brooke, Coucke, Paul, Van Laer, Lut, Loeys, Bart, Summers, Kim, Symoens, Sofie, West, Jennifer, West, Malcolm, Wordsworth, Paul (B.P.), Zankl, Andreas, Leo, Paul, Brown, Matthew, & Duncan, Emma (2013) Whole exome sequencing is an efficient, sensitive and specific method of mutation detection in osteogenesis imperfecta and Marfan syndrome. BoneKEy Reports, 2, Article number: 456 1-9.

Revez, J., Bain, Lisa, Chapman, Brett, Powell, J., Jansen, Rick, Duffy, David, Tung, Joyce, Penninx, Brenda, Visscher, Peter, de Geus, Eco, Boomsma, Dorret, Hinds, David, Martin, Nicholas, Montgomery, Grant, Ferreira, Manuel, Nyholt, Dale, Brown, Matthew, & other, and (2013) A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk. Genes and Immunity, 14(7), pp. 441-446.

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Anderson, Robert, Henry, Margaret, Taylor, Roberta, Duncan, Emma, Danoy, Patrick, Costa, Marylia, Addison, Kathryn, Tye-Din, Jason, Kotowicz, Mark, Knight, Ross, Pollock, Wendy, Nicholson, Geoffrey, Toh, Ban-Hock, Brown, Matthew, & Pasco, Julie (2013) A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways. BMC Medicine, 11, Article number: 188 1-13.

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Kenna, Tony & Brown, Matthew (2013) The role of IL-17-secreting mast cells in inflammatory joint disease. Nature Reviews Rheumatology, 9(6), pp. 375-379.

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Pimentel-Santos, Fernando Manuel, Ligeiro, Dario, Matos, Mafalda, Mourao, Ana, de Sousa, Elsa Viera, Pinto, Patricia, Ribeiro, Ana, Santos, Helena, Barcelos, Anabela, Brown, Matthew, & other, and (2012) ANKH and susceptibility to and severity of ankylosing spondylitis. Journal of Rheumatology, 39(1), pp. 131-134.

7

6

Maller, Julian, McVean, Gilean, Byrnes, Jake, Vukcevic, Damjan, Palin, Kimmo, Su, Zhan, Howson, Joanna, Auton, Adam, Myers, Simon, Brown, Matthew, & other, and (2012) Bayesian refinement of association signals for 14 loci in 3 common diseases. Nature Genetics, 44(12), pp. 1294-1301.

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Ruutu, Merja, Thomas, Gethin, Steck, Roland, Degli-Esposti, Mariapia, Zinkernagel, Martin, Alexander, Kylie, Velasco, Jared, Strutton, Geoffrey, Tran, Ai, Benham, Helen, Rehaume, Linda, Wilson, Robert, Kikly, Kristine, Davies, Julian, Pettit, Allison, Brown, Matthew, McGuckin, Michael, & Thomas, Ranjeny (2012) Beta-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice. Arthritis and Rheumatism, 64(7), pp. 2211-2222.

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Bis, Joshua, DeCarli, Charles, Smith, Albert, van der Lijn, Fedde, Crivello, Fabrice, Fornage, Myriam, Debette, Stephanie, Shulman, Joshua, Schmidt, Helena, Brown, Matthew, & other, and (2012) Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nature Genetics, 44(5), pp. 545-551.

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Su, Zhan, Gay, Laura, Strange, Amy, Palles, Claire, Band, Gavin, Whiteman, David, Lescai, Francesco, Langford, Cordelia, Nanji, Manoj, Brown, Matthew, & other, and (2012) Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nature Genetics, 44(10), pp. 1131-1136.

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Fischer, Roman, Trudgian, David, Wright, Cynthia, Thomas, Gethin, Bradbury, Linda, Brown, Matthew, Bowness, Paul, & Kessler, Benedikt (2012) Discovery of candidate serum proteomic and metabolomic biomarkers in ankylosing spondylitis. Molecular and Cellular Proteomics, 11(2), Article number: M111.013904 1-11.

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Kenna, Tony, Davidson, Stuart, Duan, Ran, Bradbury, Linda, McFarlane, Janelle, Smith, Malcolm, Weedon, Helen, Street, Shayna, Thomas, Ranjeny, Thomas, Gethin, & Brown, Matthew (2012) Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive gamma-delta T cells in patients with active ankylosing spondylitis. Arthritis and Rheumatism, 64(5), pp. 1420-1429.

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15

16

Haynes, Katelin, Pettit, Allison, Duan, Ran, Tseng, Hsu-Wen, Glant, Tibor, Brown, Matthew, & Thomas, Gethin (2012) Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors. Arthritis Research and Therapy, 14(6), Article number: R253 1-12.

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Srivastava, Brijesh, Mells, George, Cordell, Heather, Muriithi, Agnes, Brown, Matthew, Ellinghaus, Eva, Franke, Andre, Karlsen, Tom, Sandford, Richard, Alexander, Graeme, Chapman, Roger, Rushbrook, Simon, & Melum, Espen (2012) Fine mapping and replication of genetic risk loci in primary sclerosing cholangitis. Scandinavian Journal of Gastroenterology, 47(7), pp. 820-826.

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Visscher, Peter, Brown, Matthew, McCarthy, Mark, & Yang, Jian (2012) Five years of GWAS discovery. American Journal of Human Genetics, 90(1), pp. 7-24.

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Ramasamy, Adaikalavan, Kuokkanen, Mikko, Vedantam, Sailaja, Gajdos, Zofia, Couto Alves, Alexessander, Lyon, Helen, Ferreira, Manuel, Strachan, David, Zhao, Jing Hua, Brown, Matthew, & other, and (2012) Genome-wide association studies of asthma in population-based cohorts confirm known and suggested Loci and identify an additional association near HLA. PLoS One, 7(9), Article number: e44008 1-10.

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Bellenguez, Celine, Bevan, Steve, Gschwendtner, Andreas, Spencer, Chris, Burgess, Annette, Pirinen, Matti, Jackson, Caroline, Traylor, Matthew, Strange, Amy, Brown, Matthew, & other, and (2012) Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nature Genetics, 44(3), pp. 328-333.

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Wan, Yize, Shrine, Nick, Soler Artigas, Maria, Wain, Louise, Blakey, John, Moffatt, Miriam, Bush, A., Chung, Kian Fan, Cookson, William, Brown, Matthew, & other, and (2012) Genome-wide association study to identify genetic determinants of severe asthma. Thorax, 67(9), pp. 762-768.

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Estrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Duncan, Emma, Ntzani, Evangelia, Oei, Ling, Albagha, Omar, Amin, Najaf, Brown, Matthew, & other, and (2012) Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics, 44(5), pp. 491-501.

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Tsoi, Lam, Spain, Sarah, Knight, Jo, Ellinghaus, Eva, Stuart, Philip, Capon, Francesca, Ding, Jun, Li, Yanming, Tejasvi, Trilokraj, Brown, Matthew, & other, and (2012) Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nature Genetics, 44(12), pp. 1341-1348.

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Couto, Ana, Zhang, Yun, Timms, Andrew, Bruges-Armas, Jacome, Sequeiros, Jorge, & Brown, Matthew (2012) Investigating ANKH and ENPP1 in Slovakian families with chondrocalcinosis. Rheumatology International, 32(9), pp. 2745-2751.

5

Joshi, Reeti, Reveille, John, Brown, Matthew, Weisman, Michael, Ward, Michael, Gensler, Lianne, Wordsworth, Paul (B.P.), Evans, David, & Assassi, Shervin (2012) Is there a higher genetic load of susceptibility loci in familial ankylosing spondylitis? Arthritis Care and Research, 64(5), pp. 780-784.

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Waddell, Nicola, Stein, Sandra, Wagner, Sarah, Bennett, Ian, Djougarian, Anna, Melana, Stella, Jaffer, S., Holland, J., Pogo, Beatriz, Gonda, Thomas, Brown, Matthew, Leo, Paul, Saunders, Nicholas, McMillan, Nigel, Cocciardi, Sibylle, Vargas, Ana Cristina, Lakhani, Sunil, Chenevix-Trench, Georgia, Newman, Beth, & Francis, Glenn (2012) Morphological and molecular analysis of a breast cancer cluster at the ABC Studio in Toowong [Letter]. Pathology, 44(5), pp. 469-472.

Zankl, Andreas, Duncan, Emma, Leo, Paul, Clark, Graeme, Glazov, Evgeny, Addor, Marie-Claude, Herlin, Troels, Kim, Chong Ae, Leheup, Bruno, Brown, Matthew, & other, and (2012) Multicentric carpotarsal osteolysis is caused by mutations clustering in the amino-terminal transcriptional activation domain of MAFB. American Journal of Human Genetics, 90(3), pp. 494-501.

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Gruber, Barry, Couto, Ana, Bruges-Armas, Jacome, Brown, Matthew, Finzel, Kathleen, & Terkeltaub, Robert (2012) Novel ANKH amino terminus mutation (Pro5Ser) associated with early-onset calcium pyrophosphate disease with associated phosphaturia. Journal of Clinical Rheumatology, 18(4), pp. 192-195.

10

8

Bradbury, Linda, Barlow, S., Geoghegan, Frank, Hannon, Rosemary, Stuckey, Stephen, Wass, John, Russell, Graham (R.G.G.), Brown, Matthew, & Duncan, Emma (2012) Risedronate in adults with osteogenesis imperfecta type I: increased bone mineral density and decreased bone turnover, but high fracture rate persists. Osteoporosis International, 23(1), pp. 285-294.

47

38

Karunaratne, Angelo, Esapa, Christopher, Hiller, Jennifer, Boyde, Alan, Head, Rosie, Bassett, J.H. Duncan, Terrill, Nicholas, Williams, Graham, Brown, Matthew, Croucher, Peter, Brown, Steve, Cox, Roger, Barber, Asa, Thakker, Rajesh, & Gupta, Himadri (2012) Significant deterioration in nanomechanical quality occurs through incomplete extrafibrillar mineralization in rachitic bone: Evidence from in-situ synchrotron X-ray scattering and backscattered electron imaging. Journal of Bone and Mineral Research, 27(4), pp. 876-890.

55

51

Gregson, Celia, Steel, S., O'Rourke, K., Allan, K., Ayuk, J., Bhalla, Ashok, Clunie, Gavin, Crabtree, N., Fogelman, Ignac, Brown, Matthew, & other, and (2012) 'Sink or swim': An evaluation of the clinical characteristics of individuals with high bone mass. Osteoporosis International, 23(2), pp. 643-654.

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Pimentel-Santos, Fernando, Mourao, Ana, Ribeiro, Celia, Costa, Jose, Santos, Helena, Barcelos, Anabela, Pinto, Patricia, Godinho, Fatima, Cruz, Margarida, Brown, Matthew, & other, and (2012) Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, BASMI and mSASSS reference centile charts. Clinical Rheumatology, 31(3), pp. 447-454.

14

13

Keller, Margaux, Saad, Mohamad, Bras, Jose, Bettella, Francesco, Nicolaou, Nayia, Simon-Sanchez, Javier, Mittag, Florian, Buchel, Finja, Sharma, Manu, Brown, Matthew, & other, and (2012) Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Human Molecular Genetics, 21(22), pp. 4996-5009.

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Zheng, Hou-Feng, Tobias, Jon, Duncan, Emma, Evans, David, Eriksson, Joel, Paternoster, Lavinia, Yerges-Armstrong, Laura, Lehtimaki, Terho, Bergstrom, Ulrica, Brown, Matthew, & other, and (2012) WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genetics, 8(7), Article number: e1002745 1-13.

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Robinson, Philip & Brown, Matthew (2012) The genetics of Ankylosing spondylitis and Axial spondyloarthritis. Rheumatic Disease Clinics of North America, 38(3), pp. 539-553.

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Esapa, Christopher, Hough, Tertius, Testori, Sarah, Head, Rosie, Crane, Elizabeth, Chan, Carol, Evans, Holly, Bassett, J.H. Duncan, Tylzanowski, Przemko, Brown, Matthew, & other, and (2012) A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation. Journal of Bone and Mineral Research, 27(2), pp. 413-428.

32

26

Piret, Sian, Esapa, Christopher, Gorvin, Caroline, Head, Rosie, Loh, Nellie, Devuyst, Olivier, Thomas, Gethin, Brown, Steve, Brown, Matthew, Croucher, Peter, Cox, Roger, & Thakker, Rajesh (2012) A mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutation. PLoS One, 7(9), Article number: e45217 1-10.

114

11

10

Esapa, Christopher, Head, Rosie, Jeyabalan, Jeshmi, Evans, Holly, Hough, Tertius, Cheeseman, Michael, McNally, Eugene, Carr, Andrew, Thomas, Gethin, Brown, Matthew, Croucher, Peter, Brown, Steve, Cox, Roger, & Thakker, Rajesh (2012) A mouse with an N-ethyl-N-nitrosourea (ENU) induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis. PLoS One, 7(8), Article number: e43205 1-15.

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Danoy, P., Wei, M., Johanna, H., Brown, Matthew A., & Xu, H. (2011) Corrections: Association of variants in MMEL1 and CTLA4 with rheumatoid arthritis in the Han Chinese population (Annals of the Rheumatic Diseases (2011) 70, (1793-1797)). Annals of the Rheumatic Diseases, 70(12), p. 2240.

Pointon, J. J., Chapman, K., Harvey, D., Sims, A. M., Bradbury, L., Laiho, K., Kauppi, M., Kaarela, K., Tuomilehto, J., Brown, M. A., & Wordsworth, B. P. (2011) Erratum: Toll-like receptor-4 and CD14 polymorphisms in ankylosing spondylitis: Evidence of a weak association in Finns. Journal of Rheumatology, 38(4), p. 788.

Davidson, Stuart, Liu, Yu, Danoy, Patrick, Wu, Xin, Thomas, Gethin, Jiang, Lei, Sun, Linyun, Wang, Niansong, Han, Jun, Han, Huanxing, Visscher, Peter, Brown, Matthew, Xu, Huji, & other, and (2011) Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese. Annals of the Rheumatic Diseases, 70(2), pp. 289-292.

105

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Danoy, Patrick, Wei, Meng, Hadler, Johanna, Jiang, Lei, He, Dongyi, Sun, Linyun, Zeng, Xiaofeng, Visscher, Peter, Brown, Matthew, & Xu, Huji (2011) Association of variants in MMEL1 and CTLA4 with rheumatoid arthritis in the Han Chinese population. Annals of the Rheumatic Diseases, 70(10), pp. 1793-1797.

18

23

Zhou, Kaixin, Bellenguez, Celine, Spencer, Chris, Bennett, Amanda, Coleman, Ruth, Brown, Matthew, & other, and (2011) Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nature Genetics, 43(2), pp. 117-120.

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Kochan, Grazyna, Krojer, Tobias, Harvey, David, Fischer, Roman, Chen, Liye, Vollmar, Melanie, von Delft, Frank, Kavanagh, Kathryn, Brown, Matthew, Bowness, Paul, Wordsworth, Paul (B.P.), Kessler, Benedikt, & Oppermann, Udo (2011) Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming. Proceedings of the National Academy of Sciences of the United States of America, 108(19), pp. 7745-7750.

212

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Spencer, Chris, Plagnol, Vincent, Strange, Amy, Gardner, Michelle, Paisan-Ruiz, Coro, Band, Gavin, Barker, Roger, Bellenguez, Celine, Bhatia, Kailash, Brown, Matthew, & other, and (2011) Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Human Molecular Genetics, 20(2), pp. 345-353.

149

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Pointon, J. J., Harvey, D., Karaderi, T., Appleton, L. H., Farrar, C., Stone, M. A., Sturrock, R. D., Brown, M. A., & Wordsworth, B. P. (2011) Erratum: Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene. Genes and Immunity, 12(4), pp. 319-320.

2

Sawcer, Stephen, Hellenthal, Garrett, Pirinen, Matti, Spencer, Chris, Patsopoulos, Nikolaos, Moutsianas, Loukas, Dilthey, Alexander, Su, Zhan, Freeman, Colin, Brown, Matthew, & other, and (2011) Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature, 476(7359), pp. 214-219.

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Ripke, Stephan, Sanders, Alan, Kendler, Kenneth, Levinson, Douglas, Sklar, Pamela, Holmans, Peter, Lin, Dan-Yu, Duan, Jubao, Ophoff, Roel, Brown, Matthew, & other, and (2011) Genome-wide association study identifies five new schizophrenia loci. Nature Genetics, 43(10), pp. 969-976.

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Burdon, Kathryn, Macgregor, Stuart, Hewitt, Alex, Sharma, Shiwani, Chidlow, Glyn, Mills, Richard, Danoy, Patrick, Casson, Robert, Viswanathan, Ananth, Nyholt, Dale, Brown, Matthew, & other, and (2011) Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. Nature Genetics, 43(6), pp. 574-578.

216

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Duncan, Emma, Danoy, Patrick, Kemp, John, Leo, Paul, McCloskey, Eugene, Brown, Matthew, & other, and (2011) Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. PLoS Genetics, 7(4), Article number: e1001372 1-10.

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Piret, Sian, Danoy, Patrick, Dahan, Karin, Reed, Anita, Pryce, Karena, Wong, William, Torres, Rosa, Puig, Juan, Mueller, Thomas, Kotanko, Peter, Lhotta, Karl, Devuyst, Olivier, Brown, Matthew, & Thakker, Rajesh (2011) Genome-wide study of familial juvenile hyperuricaemic (gouty) nephropathy (FJHN) indicates a new locus, FJHN3, linked to chromosome 2p22.1-p21. Human Genetics, 129(1), pp. 51-58.

22

23

Ferreira, Manuel, Matheson, Melanie, Duffy, David, Marks, Guy, Hui, Jennie, Le Souef, Peter, Danoy, Patrick, Baltic, Svetlana, Nyholt, Dale, Brown, Matthew, & other, and (2011) Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. The Lancet, 378(9795), pp. 1006-1014.

53

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Zhao, Liang, Glazov, Evgeny, Pattabiraman, Diwakar, Al-Owaidi, Faisal, Zhang, Ping, Brown, Matthew, Leo, Paul, & Gonda, Thomas (2011) Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb. Nucleic Acids Research, 39(11), pp. 4664-4679.

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Evans, David, Spencer, Chris, Pointon, Jennifer, Su, Zhan, Harvey, David, Kochan, Grazyna, Oppermann, Udo, Dilthey, Alexander, Pirinen, Matti, Brown, Matthew, & other, and (2011) Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nature Genetics, 43(8), pp. 761-767.

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Ma, Gerry, Stankovich, Jim, Kilpatrick, Trevor, Binder, Michele, Field, Judith, Griffiths, Lyn, Brown, Matthew, & other, and (2011) Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility. PLoS One, 6(2), Article number: e16964 1-6.

157

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Brown, Matthew (2011) Progress in the genetics of ankylosing spondylitis. Briefings in Functional Genomics, 10(5), pp. 249-257.

31

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Pimentel-Santos, Fernando, Ligeiro, Dario, Matos, Mafalda, Mourao, Ana, Costa, Jose, Santos, Helena, Barcelos, Anabela, Godinho, Fatima, Pinto, Patricia, Brown, Matthew, & other, and (2011) Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects. Arthritis Research and Therapy, 13(2), Article number: R57 1-8.

76

73

Glazov, Evgeny, Zankl, Andreas, Donskoi, Marina, Kenna, Tony, Thomas, Gethin, Clark, Graeme, Duncan, Emma, & Brown, Matthew (2011) Whole-exome re-sequencing in a family quartet identifies POP1 mutations as the cause of a novel skeletal dysplasia. PLoS Genetics, 7(3), Article number: e1002027 1-7.

150

69

59

Gregson, Celia, Hollingworth, Peter, Williams, Martin, Petrie, Kirsten, Bullock, Alex, Brown, Matthew, Tobias, Jonathan, & Triffitt, James (2011) A novel ACVR1 mutation in the glycine/serine-rich domain found in the most benign case of a fibrodysplasia ossificans progressiva variant reported to date. Bone, 48(3), pp. 654-658.

205

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Danoy, Patrick, Pryce, Karena, Hadler, Johanna, Bradbury, Linda, Farrar, Claire, Brown, Matthew, & other, and (2010) Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease. PLoS Genetics, 6(12), Article number: e1001195 1-5.

127

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Pointon, Jennifer, Harvey, David, Karaderi, Tugce, Appleton, Louise, Farrar, Claire, Stone, M., Sturrock, Roger, Brown, Matthew, & Wordsworth, Paul (B.P.) (2010) Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene. Genes and Immunity, 11(6), pp. 490-496.

65

58

Reveille, John & Brown, Matthew (2010) Epidemiology of ankylosing spondylitis: IGAS 2009. Journal of Rheumatology, 37(12), pp. 2624-2625.

11

8

Duan, Ran, Leo, Paul, Bradbury, Linda, Brown, Matthew, & Thomas, Gethin (2010) Gene expression profiling reveals a downregulation in immune-associated genes in patients with AS. Annals of the Rheumatic Diseases, 69(9), pp. 1724-1729.

39

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Duncan, Emma & Brown, Matthew (2010) Genetic determinants of bone density and fracture risk - State of the art and future directions. Journal of Clinical Endocrinology and Metabolism, 95(6), pp. 2576-2587.

42

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Thomas, Gethin & Brown, Matthew (2010) Genetics and genomics of ankylosing spondylitis. Immunological Reviews, 233(1), pp. 162-180.

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Craddock, Nick, Hurles, Matthew, Cardin, Niall, Pearson, Richard, Plagnol, Vincent, Robson, Samuel, Vukcevic, Damjan, Barnes, Chris, Conrad, Donald, Giannoulatou, Eleni, Brown, Matthew, & other, and (2010) Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 464(7289), pp. 713-720.

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Reveille, John, Sims, Anne-Marie, Danoy, Patrick, Evans, David, Leo, Paul, Pointon, Jennifer, Jin, Rui, Zhou, Xiaodong, Bradbury, Linda, Appleton, Louise, Brown, Matthew, & other, and (2010) Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nature Genetics, 42(2), pp. 123-127.

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Thomas, Gethin & Brown, Matthew (2010) Genomics of ankylosing spondylitis. Discovery Medicine, 10(52), pp. 263-271.

24

25

Duncan, Emma & Brown, Matthew (2010) Mapping genes for osteoporosis-Old dogs and new tricks. Bone, 46(5), pp. 1219-1225.

8

5

Jensen, Cathy, Stankovich, Jim, van der Walt, Anneke, Bahlo, Melanie, Taylor, Bruce, Van der Mei, Ingrid, Foote, Simon, Kilpatrick, Trevor, Johnson, Laura, Wilkins, Ella, Field, Judith, Danoy, Patrick, Brown, Matthew, Rubio, Justin, Butzkueven, Helmut, Griffiths, Lyn, & other, and (2010) Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients. PLoS One, 5(4), Article number: e10003 1-7.

109

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Liu, Yu, Jiang, Lei, Cai, Q., Danoy, Patrick, Barnardo, M., Brown, Matthew, & Xu, Huji (2010) Predominant association of HLA-B*2704 with ankylosing spondylitis in Chinese Han patients. HLA, 75(1), pp. 61-64.

52

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Cortes, Adrian & Brown, Matthew (2010) Promise and pitfalls of the Immunochip [Commentary]. Arthritis Research and Therapy, 13, Article number: 101 1-3.

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Bahlo, Melanie, Stankovich, Jim, Danoy, Patrick, Hickey, Peter, Taylor, Bruce, Browning, Sharon, Brown, Matthew, Rubio, Justin, Griffiths, Lyn, & other, and (2010) Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies. Cancer Epidemiology Biomarkers and Prevention, 19(3), pp. 794-799.

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Pointon, Jennifer, Harvey, David, Karaderi, Tugce, Appleton, Louise, Farrar, Claire, Stone, Millicent, Sturrock, Roger, Reveille, John, Weisman, Michael, Ward, Michael, Brown, Matthew, & Wordsworth, Paul (B.P.) (2010) The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD). Annals of the Rheumatic Diseases, 69(6), pp. 1243-1246.

31

27

Evans, David, Reveille, John, Brown, Matthew, Chandran, Vinod, Gladman, Dafna, Martin, Tammy, McGovern, Dermot, Wordsworth, Paul (B.P.), & Inman, Robert (2010) The genetic basis of spondyloarthritis: SPARTAN/IGAS 2009. Journal of Rheumatology, 37(12), pp. 2626-2631.

3

2

Strange, Amy, Capon, Francesca, Spencer, Chris, Knight, Jo, Weale, Michael, Allen, Michael, Barton, Anne, Band, Gavin, Bellenguez, Celine, Bergboer, Judith, Brown, Matthew, & other, and (2010) A genome-wide asociation study identifies new psoriasis susceptibility loci and an interaction betwEn HLA-C and ERAP1. Nature Genetics, 42(11), pp. 985-990.

908

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Gandhi, Kaushal, McKay, Fiona, Cox, Mathew, Riveros, Carlos, Armstrong, Nicola, Heard, Robert, Vucic, Stephen, Williams, David, Stankovich, Jim, Brown, Matthew, Danoy, Patrick, Stewart, Graeme, Broadley, Simon, Moscato, Pablo, Lechner-Scott, Jeannette, Scott, Rodney, & Booth, David (2010) The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. Human Molecular Genetics, 19(11), pp. 2134-2143.

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Field, Judith, Browning, Sharon, Johnson, Laura, Danoy, Patrick, Varney, Michael, Tait, Brian, Gandhi, Kaushal, Charlesworth, Jac, Heard, Robert, Stewart, Graeme, Kilpatrick, Trevor, Foote, Simon, Bahlo, Melanie, Butzkueven, Helmut, Wiley, James, Booth, David, Taylor, Bruce, Brown, Matthew, Rubio, Justin, Stankovich, Jim, Griffiths, Lyn, & other, and (2010) A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis. PLoS One, 5(10), Article number: e13454 1-7.

51

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49

Harvey, David, Pointon, Jennifer, Sleator, Carole, Meenagh, Ashley, Farrar, Claire, Sun, Joel, Senitzer, David, Middleton, Derek, Brown, Matthew, & Wordsworth, Paul (B.P.) (2009) Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis. Annals of the Rheumatic Diseases, 68(4), pp. 595-598.

38

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Karaderi, Tugce, Harvey, David, Farrar, Claire, Appleton, Louise, Stone, Millicent, Sturrock, Roger, Brown, Matthew, Wordsworth, Paul (B.P.), & Pointon, Jennifer (2009) Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-analysis of published series. Rheumatology, 48(4), pp. 386-389.

99

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Davidson, Stuart, Wu, Xin, Liu, Yu, Wei, Meng, Danoy, Patrick, Thomas, Gethin, Cai, Qing, Sun, Linyun, Duncan, Emma, Wang, Niansong, other, and, & Brown, Matthew (2009) Association of ERAP1, but not IL23R, with ankylosing spondylitis in a Han Chinese population. Arthritis and Rheumatism, 60(11), pp. 3263-3268.

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Pimentel-Santos, Fernando, Ligeiro, Dario, Matos, Mafalda, Mourão, Ana, Brown, Matthew, & other, and (2009) Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population. Clinical and Experimental Rheumatology, 27(5), pp. 800-806.

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Brown, Matthew, Newton, Julia, Harney, Sinead, & Wordsworth, Paul (B.P.) (2009) Challenges in mapping non-HLA-DRB1 major histocompatibility genes in rheumatoid arthritis: Comment on the article by Vignal et al. Arthritis and Rheumatism, 60(7), p. 2207.

Timpson, Nicholas, Tobias, Jonathan, Richards, J. Brent, Soranzo, Nicole, Duncan, Emma, Sims, Anne-Marie, Whittaker, Pamela, Kumanduri, Vasudev, Zhai, Guangju, Glaser, Beate, Brown, Matthew, & other, and (2009) Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Human Molecular Genetics, 18(8), pp. 1510-1517.

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Maksymowych, Walter & Brown, Matthew (2009) Genetics of ankylosing spondylitis and rheumatoid arthritis: Where are we at currently, and how do they compare? Clinical and Experimental Rheumatology, 27(S55), S20-S25.

22

19

Newton-Cheh, Christopher, Johnson, Toby, Gateva, Vesela, Tobin, Martin, Bochud, Murielle, other, and, & Brown, Matthew (2009) Genome-wide association study identifies eight loci associated with blood pressure. Nature Genetics, 41(6), pp. 666-676.

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Bahlo, Melanie, Booth, David, Broadley, Simon, Brown, Matthew, Foote, Simon, Griffiths, Lyn, Kilpatrick, Trevor, Lechner-Scott, Jeannette, Moscato, Pablo, Perreau, Victoria, & other, and (2009) Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nature Genetics, 41(7), pp. 824-828.

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Barrett, Jeffrey, Lee, James, Lees, Charles, Prescott, Natalie, Anderson, Carl, Brown, Matthew, & other, and (2009) Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nature Genetics, 41(12), pp. 1330-1334.

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3

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Harvey, David, Pointon, Jennifer, Evans, David, Karaderi, Tugce, Farrar, Claire, Appleton, Louise, Sturrock, Roger, Stone, Millicent, Oppermann, Udo, Brown, Matthew, & Wordsworth, Paul (B.P.) (2009) Investigating the genetic association between ERAP1 and ankylosing spondylitis. Human Molecular Genetics, 18(21), pp. 4204-4212.

121

Petrie, Kirsten, Lee, Wen, Bullock, Alex, Pointon, Jennifer, Smith, Roger, Russell, Graham (R.G.G.), Brown, Matthew, Wordsworth, Paul (B.P.), & Triffitt, James (2009) Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients. PLoS One, 4(3), pp. 1-4.

111

74

66

Angelicheva, Dora, Tournev, Ivailo, Guergueltcheva, Velina, Mihaylova, Violeta, Azmanov, Dimitar, Brown, Matthew, & other, and (2009) Partial epilepsy syndrome in a Gypsy family linked to 5q31.3-q32. Epilepsia, 50(7), pp. 1679-1688.

16

15

Brown, Matthew (2009) Progress in spondylarthritis. Progress in studies of the genetics of ankylosing spondylitis. Arthritis Research and Therapy, 11(5), pp. 1-6.

20

16

Poulsen, Anne, Bush, Robert, Tirendi, Joleen, Ziviani, Jenny, Abbott, Rebecca, Macdonald, Doune, Brown, Matthew, & Leong, Gary (2009) Research around practice partnerships: An example of building partnerships to address overweight and obesity in children. Australian Journal of Primary Health, 15(4), pp. 285-293.

2

Chen, Yueh-Sheng, Yan, Weixing, Geczy, Carolyn, Brown, Matthew, & Thomas, Ranjeny (2009) Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis. Arthritis Research and Therapy, 11(2), pp. 1-11.

104

93

Brown, Matthew (2008) Breakthroughs in genetic studies of ankylosing spondylitis. Rheumatology, 47(2), pp. 132-137.

111

101

Feletar, Marie, Foley, Peter, & Brown, Matthew (2008) Developments in psoriasis and psoriatic arthritis. Drug Discovery Today: Disease Mechanisms, 5(1), pp. 47-54.

4

Kain, Tracey, Zochling, Jane, Taylor, Andrew, Manolios, Nicholas, Smith, Malcolm, Reed, Mark, Brown, Matthew, & Schachna, Lionel (2008) Evidence-based recommendations for the diagnosis of ankylosing spondylitis: Results from the Australian 3E initiative in rheumatology. Medical Journal of Australia, 188(4), pp. 235-237.

9

8

Kain, Tracey, Zochling, Jane, Taylor, Andrew, Manolios, Nicholas, Smith, Malcolm, Reed, Mark, Brown, Matthew, & Schachna, Lionel (2008) Evidence-based recommendations for the monitoring and treatment of ankylosing spondylitis: Results from the Australian 3E initiative in rheumatology. International Journal of Rheumatic Diseases, 11(1), pp. 45-49.

Harney, Sinead, Vilariño-Güell, Carles, Sims, Anne-Marie, Lawrence, Robert, Cardon, Lon, Newton, Julia, Meisel, Christian, Pointon, Jennifer, Darke, Chris, Athanasou, Nicholas, Wordsworth, Paul (B.P.), & Brown, Matthew (2008) Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis. Rheumatology, 47(12), pp. 1761-1767.

46

40

Sims, Anne-Marie, Shephard, Neil, Carter, Kim, Doan, Tracy, Dowling, Alison, other, and, & Brown, Matthew (2008) Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes. Journal of Bone and Mineral Research, 23(4), pp. 499-506.

139

124

Duncan, Emma & Brown, Matthew (2008) Genetic studies in osteoporosis - The end of the beginning. Arthritis Research and Therapy, 10(5), Article number: 214 1-8.

133

24

20

Danoy, Patrick & Brown, Matthew (2008) Genome-wide association studies and musculoskeletal diseases. Future Rheumatology, 3(6), pp. 537-542.

Brown, Matthew (2008) Matters Arising: Zhu et al, "A novel gene variation of TNFa associated with ankylosing spondylitis: A reconfirmed study". Annals of the Rheumatic Diseases, 67(3), p. 434.

3

Sims, A-M., Timms, A., Bruges-Armas, Jacome, Burgos-Vargas, R., Brown, Matthew, & other, and (2008) Prospective meta-analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis. Annals of the Rheumatic Diseases, 67(9), pp. 1305-1309.

110

99

Kaplan, Frederick, Xu, Meiqi, Feldman, George, Brown, Matthew, Cho, Tae-Joon, Choi, Inho, Connor, James, Longo Ribeiro Delai, P., Economides, Aris, Glaser, David, & other, and (2008) Response to "mutations of the Noggin and of the activin A type I receptor genes in fibrodysplasia ossificans progressiva (FOP)" by Lucotte et al. Genetic Counseling, 19(3), pp. 357-359.

3

2

Pointon, Jennifer, Chapman, Kay, Harvey, David, Sims, Anne-Marie, Bradbury, Linda, Laiho, Kari, Kauppi, Markku, Kaarela, Kalevi, Tuomilehto, Jaakko, Brown, Matthew, & Wordsworth, Paul (B.P.) (2008) Toll-like receptor 4 and CD14 polymorphisms in ankylosing spondylitis: Evidence of a weak association in finns. Journal of Rheumatology, 35(8), pp. 1609-1612.

7

8

Burton, Paul, Clayton, David, Cardon, Lon, Craddock, Nick, Deloukas, Panos, other, and, & Brown, Matthew (2007) Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics, 39(11), pp. 1329-1337.

1,234

1,153

Carter, K., Pluzhnikov, Anna, Timms, Andrew, Miceli-Richard, C., Bourgain, Catherine, Brown, Matthew, & other, and (2007) Combined analysis of three whole genome linkage scans for Ankylosing Spondylitis. Rheumatology, 46(5), pp. 763-771.

56

49

Peach, Chris, Zhang, Yun, Dunford, James, Brown, Matthew, & Carr, Andrew (2007) Cuff tear arthropathy: Evidence of functional variation in pyrophosphate metabolism genes. Clinical Orthopaedics and Related Research, pp. 67-72.

34

26

Tobias, Jonathan, Steer, Colin, Vilariño-Güell, Carles, & Brown, Matthew (2007) Effect of an estrogen receptor-a intron 4 polymorphism on fat mass in 11-year-old children. Journal of Clinical Endocrinology and Metabolism, 92(6), pp. 2286-2291.

19

16

Tobias, Jonathan, Steer, Colin, Vilariño-Güell, Carles, & Brown, Matthew (2007) Estrogen receptor a regulates area-adjusted bone mineral content in late pubertal girls. Journal of Clinical Endocrinology and Metabolism, 92(2), pp. 641-647.

16

15

Couto, Ana & Brown, Matthew (2007) Genetic factors in the pathogenesis of CPPD crystal deposition disease. Current Rheumatology Reports, 9(3), pp. 231-236.

12

Burton, Paul, Clayton, David, Cardon, Lon, Craddock, Nick, Deloukas, Panos, Bradbury, Linda, Brown, Matthew, & other, and (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447(7145), pp. 661-678.

8,304

7,542

Brown, Matthew (2007) Human leucocyte antigen-B27 and ankylosing spondylitis. Internal Medicine Journal, 37(11), pp. 739-740.

23

19

Zhang, Yun, Brown, Matthew, Peach, Chris, Russell, Graham (R.G.G.), & Wordsworth, Paul (B.P.) (2007) Investigation of the role of ENPP1 and TNAP genes in chondrocalcinosis. Rheumatology, 46(4), pp. 586-589.

24

22

Nejentsev, Sergey, Howson, Joanna, Walker, Neil, Szeszko, Jeffrey, Field, Sarah, Stevens, Helen, Reynolds, Pamela, Hardy, Matthew, King, Erna, other, and, & Brown, Matthew (2007) Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature, 450(7171), pp. 887-892.

488

450

Sims, Anne-Marie, Barnardo, M., Herzberg, I., Bradbury, Linda, Calin, Andrei, Wordsworth, Paul (B.P.), Darke, Chris, & Brown, Matthew (2007) Non-B27 MHC associations of ankylosing spondylitis. Genes and Immunity, 8(2), pp. 115-123.

42

36

Vilariño-Güell, Carles, Miles, Lisa, Duncan, Emma, Ralston, Stuart, Brown, Matthew, & other, and (2007) PTHR1 polymorphisms influence BMD variation through effects on the growing skeleton. Calcified Tissue International, 81(4), pp. 270-278.

22

17

Koay, M, Tobias, Jonathan, Leary, Sam, Steer, Colin, Vilariño-Güell, Carles, & Brown, Matthew (2007) The effect of LRP5 polymorphisms on bone mineral density is apparent in childhood. Calcified Tissue International, 81(1), pp. 1-9.

45

38

Couto, Ana, Bruges-Armas, Jacome, Peach, Chris, Chapman, Kay, Brown, Matthew, Wordsworth, Paul (B.P.), & Zhang, Yun (2007) A novel LEMD3 mutation common to patients with osteopoikilosis with and without melorheostosis. Calcified Tissue International, 81(2), pp. 81-84.

35

29

Schachna, Lionel & Brown, Matthew (2006) Australian data do not support current pharmaceutical benefits scheme criteria for use of tumour necrosis factor-a inhibitors in ankylosing spondylitis. Internal Medicine Journal, 36(11), pp. 755-756.

Bruges-Armas, Jacome, Couto, Ana, Timms, Andrew, Santos, Margarida, Brown, Matthew, & other, and (2006) Ectopic calcification among families in the Azores: Clinical and radiologic manifestations in families with diffuse idiopathic skeletal hyperostosis and chondrocalcinosis. Arthritis and Rheumatism, 54(4), pp. 1340-1349.

40

28

Harrison, Pille, Pointon, Jennifer, Farrar, Claire, Brown, Matthew, & Wordsworth, Paul (B.P.) (2006) Effects of PTPN22 C1858T polymorphism on susceptibility and clinical characteristics of British Caucasian rheumatoid arthritis patients. Rheumatology, 45(8), pp. 1009-1011.

58

49

Jaakkola, Elisa, Herzberg, I., Laiho, K., Barnardo, M., Pointon, J., Brown, Matthew, & other, and (2006) Finnish HLA studies confirm the increased risk conferred by HLA-B27 homozygosity in ankylosing spondylitis. Annals of the Rheumatic Diseases, 65(6), pp. 775-780.

112

91

Lovelock, Paul, Healey, Sue, Au, Wendy, Sum, Eleanor, Tesoriero, Andrea, Brown, Matthew, & other, and (2006) Genetic, functional, and histopathological evaluation of two C-terminal BRCA1 missense variants. Journal of Medical Genetics, 43(1), pp. 74-83.

36

34

Harney, Sinead, Timperley, Jonathan, Daly, Caroline, Harin, Alice, James, Tim, Brown, Matthew, Banning, Adrian, Fox, Kim, Donnelly, Simon, & Wordsworth, Paul (B.P.) (2006) Letter: Brain natriuretic peptide is a potentially useful screening tool for the detection of cardiovascular disease in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 65(1), pp. 136-137.

23

22

Brown, Matthew (2006) Non-major-histocompatibility-complex genetics of ankylosing spondylitis. Best Practice and Research in Clinical Rheumatology, 20(3), pp. 611-621.

36

30

Chou, C-T., Timms, Andrew, Wei, J., Tsai, W., Wordsworth, Paul (B.P.), & Brown, Matthew (2006) Replication of association of IL1 gene complex members with ankylosing spondylitis in Taiwanese Chinese. Annals of the Rheumatic Diseases, 65(8), pp. 1106-1109.

68

64

Reveille, John & Brown, Matthew (2006) The pathogenesis of Ankylosing spondylitis. In Weisman, M H, Reveille, J D, & van der Heijde, D (Eds.) Ankylosing spondylitis and the spondyloarthropathies. Mosby, United States of America, pp. 21-37.

5

Shore, Eileen, Xu, Meiqi, Feldman, George, Fenstermacher, David, Cho, Tae-Joon, Brown, Matthew, & other, and (2006) A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nature Genetics, 38(5), pp. 525-527.

1,016

933

Hsieh, Hsin-Ju, Christina, Palmer, Harney, Sinead, Wordsworth, Paul (B.P.), Brown, Matthew, & Sinsheimer, Janet (2006) The v-MFG test: Investigating maternal, offspring and maternal-fetal genetic incompatibility effects on disease and viability. Genetic Epidemiology, 30(4), pp. 333-347.

16

17

Harney, S., Wordsworth, B. P., Brown, M A, Laivoranta-Nyman, S., Ilonen, J., Hermann, R., M�tt�nen, T., Toivanen, A., Tuokko, J., Luukkainen, R., Hakala, M., Hannonen, P., Korpela, M., & Yli-Kerthula, U. (2005) Matters Arising: HLA-DR-DQ haplotypes and genotypes in Finnish patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 64(4), p. 655.

Brown, Matthew A. (2005) Antibody treatments of inflammatory arthritis. Current Medicinal Chemistry, 12(25), pp. 2943-2946.

16

13

Zhang, Y., Johnson, K., Russell, R. G. G., Wordsworth, B. P., Carr, A. J., Terkeltaub, R. A., & Brown, Matthew A. (2005) Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5′-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate. Arthritis and Rheumatism, 52(4), pp. 1110-1117.

74

55

Harney, S. M. J., Meisel, C., Sims, A. M., Woon, P. Y., Wordsworth, B. P., & Brown, M. A. (2005) Genetic and genomic studies of PADI4 in rheumatoid arthritis. Rheumatology, 44(7), pp. 869-872.

65

60

Koay, M. A. & Brown, Matthew A. (2005) Genetic disorders of the LRP5-Wnt signalling pathway affecting the skeleton. Trends in Molecular Medicine, 11(3), pp. 129-137.

64

58

Zhang, Y. & Brown, M.A. (2005) Genetic studies of chondrocalcinosis. Current Opinion in Rheumatology, 17(3), pp. 330-335.

23

18

Brown, Matthew A. (2005) Genetic studies of osteoporosis: A rethink required. Calcified Tissue International, 76(5), pp. 319-325.

10

12

Timms, A. E., Crane, A. M., Sims, A. M., Cordell, H. J., Bradbury, L. A., Abbott, A., Coyne, M. R. E., Beynon, O., Herzberg, I., Duff, G. W., Calin, A., Cardon, L. R., Wordsworth, B. P., & Brown, Matthew A. (2004) The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis. American Journal of Human Genetics, 75(4), pp. 587-595.

128

109

Brophy, S., Hickey, S., Menon, A., Taylor, G., Bradbury, L., Hamersma, J., Brown, M. A., & Calin, A. (2004) Concordance of disease severity among family members with ankylosing spondylitis? Journal of Rheumatology, 31(9), pp. 1775-1778.

48

47

Newton, J. L., Harney, S. M. J., Timms, A. E., Sims, A. M., Rockett, K., Darke, C., Wordsworth, B. P., Kwiatkowski, D., & Brown, Matthew A. (2004) Dissection of class III major histocompatibility complex haplotypes associated with rheumatoid arthritis. Arthritis and Rheumatism, 50(7), pp. 2122-2129.

51

47

Sims, A. M., Wordsworth, B. P., & Brown, M.A. (2004) Genetic susceptibility to ankylosing spondylitis. Current Molecular Medicine, 4(1), pp. 13-20.

61

52

Koay, M. Audrey, Woon, Peng Y., Zhang, Yun, Miles, Lisa J., Duncan, Emma L., Ralston, Stuart H., Compston, Juliet E., Cooper, Cyrus, Keen, Richard, Langdahl, Bente L., MacLelland, Alasdair, O'Riordan, Jeffrey, Pols, Huibert A., Reid, David M., Uitterlinden, Andre G., Wass, John A.H., & Brown, Matthew A. (2004) Influence of LRP5 polymorphisms on normal variation in BMD. Journal of Bone and Mineral Research, 19(10), pp. 1619-1627.

123

110

Ploski, R., Bednarczuk, T., Hiromatsu, Y., Newton, J., Kwiatkowski, D., Wordsworth, P., & Brown, Matthew A. (2004) Letter Reply: Distribution of TNFA haplotypes in healthy Caucasians: Comment on the articles by Newton et al and Zeggini et al. Arthritis and Rheumatism, 50(6), pp. 2034-2036.

1

Stratakis, C.A., Bertherat, J., Carney, J.A., Brown, M.A., Morita, H., Nagai, R., Basson, C.T., Veugelers, M., & McDermott, D.A. (2004) Mutation of perinatal myosin heavy chain. New England Journal of Medicine, 351(24), pp. 2556-2558.

14

Jaakkola, E., Crane, A. M., Laiho, K., Herzberg, I., Sims, A. M., Bradbury, L., Calin, A., Brophy, S., Kauppi, M., Kaarela, K., Wordsworth, B. P., Tuomilehto, J., & Brown, M. A. (2004) The effect of transforming growth factor β1 gene polymorphisms in ankylosing spondylitis. Rheumatology, 43(1), pp. 32-38.

28

19

Jaakkola, E., Herzberg, I., Crane, A. M., Pointon, J. J., Laiho, K., Kauppi, M., Kaarela, K., Wordsworth, B. P., Tuomilehto, J., & Brown, M. A. (2004) A novel human leucocyte antigen-DRB1 genotyping method based on multiplex primer extension reactions. Tissue Antigens, 64(1), pp. 88-95.

7

6

Newton, J. L., Harney, S. M. J., Wordsworth, B. P., & Brown, M. A. (2004) A review of the MHC genetics of rheumatoid arthritis. Genes and Immunity, 5(3), pp. 151-157.

200

181

Brown, Matthew A., Brophy, S., Bradbury, L., Hamersma, J., Timms, A., Laval, S., Cardon, L., Calin, A., & Wordsworth, B. P. (2003) Identification of major loci controlling clinical manifestations of ankylosing spondylitis. Arthritis and Rheumatism, 48(8), pp. 2234-2239.

72

60

Goedecke, V., Crane, A. M., Jaakkola, E., Kaluza, W., Laiho, K., Weeks, D. E., Wilson, J., Kauppi, M., Kaarela, K., Tuomilehto, J., Wordsworth, B. P., & Brown, M. A. (2003) Interleukin 10 polymorphisms in ankylosing spondylitis. Genes and Immunity, 4(1), pp. 74-76.

28

21

Timms, A. E., Zhang, Y., Bradbury, L., Wordsworth, B. P., & Brown, M. A. (2003) Investigation of the role of ANKH in ankylosing spondylitis. Arthritis and Rheumatism, 48(10), pp. 2898-2902.

58

49

Harney, S., Newton, J., Milicic, A., Brown, M. A., & Wordsworth, B. P. (2003) Non-inherited maternal HLA alleles are associated with rheumatoid arthritis. Rheumatology, 42(1), pp. 171-174.

39

32

Jevon, M., Hirayama, T., Brown, M. A., Wass, J. A. H., Sabokbar, A., Ostelere, S., & Athanasou, N. A. (2003) Osteoclast formation from circulating precursors in osteoporosis. Scandinavian Journal of Rheumatology, 32(2), pp. 95-100.

30

31

Duncan, Emma L., Cardon, Lon R., Sinsheimer, Janet S., Wass, John A.H., & Brown, Matthew A. (2003) Site and gender specificity of inheritance of bone mineral density. Journal of Bone and Mineral Research, 18(8), pp. 1531-1538.

98

87

Wynne, F., Drummond, F. J., Daly, M., Brown, M.A., Shanahan, F., Molloy, M. G., & Quanel, K. A. (2003) Suggestive linkage of 2p22-25 and 11q12-13 with low bone mineral density at the lumbar spine in the Irish population. Calcified Tissue International, 72(6), pp. 651-658.

35

Newton, J., Brown, Matthew A., Milicic, A., Ackerman, H., Darke, C., Wilson, J. N., Wordsworth, B. P., & Kwiatkowski, D. (2003) The effect of HLA-DR on susceptibility to rheumatoid arthritis is influenced by the associated lymphotoxin α-tumor necrosis factor haplotype. Arthritis and Rheumatism, 48(1), pp. 90-96.

46

45

Milicic, A., Misra, R., Agrawal, S., Aggarwal, A., Brown, M A, & Wordsworth, B. P. (2002) The F158V polymorphism in FcγRIIIA shows disparate associations with rheumatoid arthritis in two genetically distinct populations. Annals of the Rheumatic Diseases, 61(11), pp. 1021-1023.

26

28

Williams, C. J., Zhang, Y., Timms, A., Bonavita, G., Caeiro, F., Broxholme, J., Cuthbertson, J., Jones, Y., Marchegiani, R., Reginato, A., Graham Russell, R., Wordsworth, B. P., Carr, A. J., & Brown, Matthew A. (2002) Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKH. American Journal of Human Genetics, 71(4), pp. 985-991.

104

82

Timms, A. E., Sathananthan, R., Bradbury, L.A., Athanasou, N. A., & Brown, M A (2002) Genetic testing for haemochromatosis in patients with chondrocalcinosis. Annals of the Rheumatic Diseases, 61(8), pp. 745-747.

132

35

28

Brown, M.A., Crane, A. M., & Wordsworth, B. P. (2002) Genetic aspects of susceptibility, severity, and clinical expression in ankylosing spondylitis. Current Opinion in Rheumatology, 14(4), pp. 354-360.

30

17

Timms, A. E., Zhang, Y., Russell, R. G. G., & Brown, M. A. (2002) Genetic studies of disorders of calcium crystal deposition. Rheumatology, 41(7), pp. 725-729.

124

116

Brown, M.A., Wordsworth, B.P., & Reveille, J. D. (2002) Genetics of ankylosing spondylitis. Clinical and Experimental Rheumatology, 20(6SUP28), S43-S49.

76

64

Milicic, A., Lee, D., Brown, M. A., Darke, C., & Wordsworth, B. P. (2002) HLA-DR/DQ haplotype in rheumatoid arthritis: Novel allelic associations in UK Caucasians. Journal of Rheumatology, 29(9), pp. 1821-1826.

34

30

Brown, M A, Crane, A. M., Wordsworth, B. P., Said-Nahal, R., Miceli-Richard, C., & Breban, M. (2002) Matters Arising: Role of HLA genes in familial spondyloarthropathy. Annals of the Rheumatic Diseases, 61(8), pp. 764-765.

1

2

Crane, A.M., Bradbury, L.A., Van Heel, D.A., McGovern, D.P.B., Brophy, S., Rubin, L., Siminovitch, K.A., Wordsworth, B.P., Calin, A., & Brown, M.A. (2002) Role of NOD2 variants in spondylarthritis. Arthritis and Rheumatism, 46(6), pp. 1629-1633.

91

75

MacKay, K., Eyre, S., Myerscough, A., Milicic, A., Barton, A., Laval, S., Barrett, J., Lee, D., White, S., John, S., Brown, Matthew A., Bell, J., Silman, A., Ollier, W., Wordsworth, P., & Worthington, J. (2002) Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom. Arthritis and Rheumatism, 46(3), pp. 632-639.

189

160

Milicic, A., Brown, M. A., & Wordsworth, B. P. (2001) Polymorphism in codon 17 of the CTLA-4 gene (+49 A/G) is not associated with susceptibility to rheumatoid arthritis in British Caucasians. Tissue Antigens, 58(1), pp. 50-54.

25

26

Brown, Matthew A., Haughton, M. A., Grant, S. F. A., Gunnell, A. S., Henderson, N. K., & Eisman, J. A. (2001) Genetic control of bone density and turnover: Role of the collagen 1α1, estrogen receptor, and vitamin D receptor genes. Journal of Bone and Mineral Research, 16(4), pp. 758-764.

99

72

Laval, S.H., Timms, A., Edwards, S., Bradbury, L.A., Brophy, S., Milicic, A., Rubin, L., Siminovitch, K.A., Weeks, D.E., Calin, A., Wordsworth, B.P., & Brown, M.A. (2001) Whole-genome screening in ankylosing spondylitis: Evidence of non-MHC genetic-susceptibility loci. American Journal of Human Genetics, 68(4), pp. 918-926.

236

202

Brown, Matthew A., Bradlow, J., & Gray, A. M. (2001) Cost effectiveness of bone density measurements. Post reproductive health, 7(3), pp. 130-135.

8

Hamersma, J., Cardon, L.R., Bradbury, L.A., Brophy, S., Van Der Horst-Bruinsma, I., Calin, A., & Brown, M.A. (2001) Is disease severity in ankylosing spondylitis genetically determined? Arthritis and Rheumatism, 44(6), pp. 1396-1400.

125

101

Milicic, A., Lindheimer, F., Laval, S., Rudwaleit, M., Ackerman, H., Wordsworth, P., Hohler, T., & Brown, M. A. (2000) Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis. Genes and Immunity, 1(7), pp. 418-422.

56

49

Brown, Matthew A., Edwards, S., Hoyle, E., Campbell, S., Laval, S., Daly, A. K., Pile, K. D., Calin, A., Ebringer, A., Weeks, D. E., & Wordsworth, B. P. (2000) Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis. Human Molecular Genetics, 9(11), pp. 1563-1566.

84

64

Brown, M A, Laval, S. H., Brophy, S., & Calin, A. (2000) Recurrence risk modelling of the genetic susceptibility to ankylosing spondylitis. Annals of the Rheumatic Diseases, 59(11), pp. 883-886.

243

216

Carter, N., Williamson, L., Kennedy, L. G., Brown, M. A., & Wordsworth, B. P. (2000) Susceptibility to ankylosing spondylitis. Rheumatology, 39(4), p. 445.

25

23

Hoyle, E., Laval, S. H., Calin, A., Wordsworth, B. P., & Brown, Matthew A. (2000) The X-chromosome and susceptibility to ankylosing spondylitis. Arthritis and Rheumatism, 43(6), pp. 1353-1355.

48

38

Brown, M.A. & Eisman, J. A. (2000) The genetics of osteoporosis: Future diagnostic possibilities. Clinics in Laboratory Medicine, 20(3), pp. 527-547.

4

3

Duncan, Emma L., Brown, Matthew A., Sinsheimer, Janet, Bell, John, Carr, Andrew J., Wordsworth, B. Paul, & Wass, John A.H. (1999) Suggestive linkage of the parathyroid receptor type 1 to osteoporosis. Journal of Bone and Mineral Research, 14(12), pp. 1993-1999.

136

123

Brown, Matthew & Wordsworth, Paul (1998) Author's reply to: Ankylosing spondylitis: evidence for a non-HLA-B*27 protective effect, Sjef Van Der Linden, Desieree Van Der Heijde. Annals of the Rheumatic Diseases, 57(4), pp. 263-264.

Brown, M. & Wordsworth, P. (1998) Genotyping HLA-B27 in spondyloarthropathies. The Journal of Rheumatology, 25(4), pp. 820-821.

5

3

Brown, M. A. & Wordsworth, B. P. (1998) Genetic studies of common rheumatological diseases. British Journal of Rheumatology, 37(8), pp. 818-823.

6

Pal, A., Hill, M., Wordsworth, P., & Brown, M. (1998) Secretor status and ankylosing spondylitis. Journal of Rheumatology, 25(2), pp. 318-319.

6

3

Brown, Matthew A., Kennedy, L. G., Darke, C., Gibson, K., Pile, K. D., Shatford, J. L., Taylor, A., Calin, A., & Wordsworth, B. P. (1998) The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis. Arthritis and Rheumatism, 41(3), pp. 460-465.

127

109

Brown, Matthew A., Pile, K. D., Kennedy, L. G., Campbell, D., Andrew, L., March, R., Shatford, J. L., Weeks, D. E., Calin, A., & Wordsworth, B. P. (1998) A genome-wide screen for susceptibility loci in ankylosing spondylitis. Arthritis and Rheumatism, 41(4), pp. 588-595.

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