Manipulating fibrin structure of hematomas enhances large bone defects healing
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Xin Wang Thesis (PDF 14MB) |
Description
Hematomas (blood clots) are known important factors in early stages of fracture repair. This project characterized the differences in hematomas between normal healing and delayed healing in bone defects. It was found that manipulation of the hematoma structure can significantly improve bone healing and result in significantly increased bone formation. This project will lead to the development of innovative treatment of large bone defects, fractures, and bone non-union.
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| ID Code: | 100030 |
|---|---|
| Item Type: | QUT Thesis (PhD by Publication) |
| Supervisor: | Xiao, Yin, Crawford, Ross, Glatt, Vaida, & Prasadam, Indira |
| Additional Information: | Recipient of the 2016 Outstanding Doctoral Thesis Award |
| Keywords: | Large bone defect, Hematoma, Fibrin clot, Proinflammatory cytokines, Structural properties, ODTA |
| DOI: | 10.5204/thesis.eprints.100030 |
| Divisions: | Past > Institutes > Institute of Health and Biomedical Innovation Past > QUT Faculties & Divisions > Science & Engineering Faculty Past > Schools > School of Chemistry, Physics & Mechanical Engineering |
| Institution: | Queensland University of Technology |
| Deposited On: | 24 Feb 2017 06:57 |
| Last Modified: | 29 Sep 2017 14:42 |
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