An investigation of the impact of bacterial diversity, pathogenic determinants and biofilms on chronic wounds

(2017) An investigation of the impact of bacterial diversity, pathogenic determinants and biofilms on chronic wounds. PhD thesis, Queensland University of Technology.

Description

The researcher investigated the abundance and diversity of bacteria in chronic wounds. Chronic wounds are a significant public health burden and associated with complex polymicrobial communities. Bacterial colonization has been hypothesized to be one of the main underlying causes of chronic wounds and leads to detrimental effects on wound healing. Next-generation sequencing technologies were utilized to identify possible bacterial biomarkers to predict wound healing trajectory. Overall, bacterial bioburden and their molecular characteristics were found to be associated with and predictive of poor wound healing outcomes. This research has been presented at conferences and in publications.

Impact and interest:

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88 since deposited on 19 Sep 2017
28 in the past twelve months

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ID Code: 110339
Item Type: QUT Thesis (PhD)
Supervisor: Huygens, Flavia & Rathnayake, Irani
Keywords: Anaerobes, Bacterial diversity, Bacterial load, Bioburden, Biofilm, Chronic wounds, Staphylococci, Wound healing
DOI: 10.5204/thesis.eprints.110339
Divisions: Past > QUT Faculties & Divisions > Faculty of Health
Current > Schools > School of Biomedical Sciences
Institution: Queensland University of Technology
Deposited On: 19 Sep 2017 07:08
Last Modified: 16 Mar 2021 04:36