Neuro 2D correlated spectroscopy identifies neuro deregulation in soldiers exposed to blast prior to discernible changes by conventional imaging

Galloway, Graham, , , Trickey, Katie, , Keane, Theresa, & (2017) Neuro 2D correlated spectroscopy identifies neuro deregulation in soldiers exposed to blast prior to discernible changes by conventional imaging. In International Society for Magnetic Resonance in Medicine, 2017-04-22 - 2017-04-28, Honolulu, United States, USA.

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Description

This pilot study reports clear deregulation in the neurochemistry of defense personnel exposed to repeated blast. The changes recorded are different to those reported for mTBI, PTSD and chronic pain. No differences between blast exposed and healthy were recorded by MRI sequences T1WI, FLAIR or SWI. In vivo neuro 2D spectroscopy recorded deregulation with PC and GPC, NAA and GABA all decreased compared to the healthy non exposed brain. We we did not observe any changes in the fucosolated glycans, which are reflective of pain, repetitive brain injury and/or cognitive deficit.

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ID Code: 112552
Item Type: Contribution to conference (Abstract)
Refereed: No
Measurements or Duration: 1 pages
Pure ID: 33178618
Divisions: Past > QUT Faculties & Divisions > Faculty of Health
Past > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Consult author(s) regarding copyright matters
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Deposited On: 25 Oct 2017 02:09
Last Modified: 01 Mar 2024 22:23